ChemicalBook > CAS DataBase List > BISINDOLYLMALEIMIDE VII
BISINDOLYLMALEIMIDE VII
- Product Name
- BISINDOLYLMALEIMIDE VII
- CAS No.
- 137592-47-3
- Chemical Name
- BISINDOLYLMALEIMIDE VII
- Synonyms
- BISINDOLYLMALEIMIDE VII;1H-Pyrrole-2,5-dione, 3-(1H-indol-3-yl)-4-[1-[3-(1-piperazinyl)propyl]-1H-indol-3-yl]-
- CBNumber
- CB2246763
- Molecular Formula
- C27H27N5O2
- Formula Weight
- 453.54
- MOL File
- 137592-47-3.mol
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BISINDOLYLMALEIMIDE VII Property
- Boiling point:
- 761.6±60.0 °C(Predicted)
- Density
- 1.39±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO: soluble
- form
- solid
- pka
- 8.18±0.60(Predicted)
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- B3681
- Product name
- Bisindolylmaleimide VII
- Purity
- 96% (TLC), solid
- Packaging
- 1mg
- Price
- $125
- Updated
- 2025/07/31
American Custom Chemicals Corporation
- Product number
- PRK0000426
- Product name
- BISINDOLYLMALEIMIDE VII
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $171.15
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- PRK0000426
- Product name
- BISINDOLYLMALEIMIDE VII
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.72
- Updated
- 2021/12/16
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BISINDOLYLMALEIMIDE VII Chemical Properties,Usage,Production
Uses
Bisindolylmaleimide VII is a potent inhibitor of calmodulin with high affinity for calmodulin (Kd=186.2 nM). Bisindolylmaleimide VII is used to study the role of calmodulin in cancer, neurodegenerative diseases, and muscle dysfunction[1].
Biological Activity
Selective inhibitor of protein kinase C.
References
[1] Sosa-Peinado, et al. Bisindolylmaleimides new ligands of CaM Protein. Molecules 27.21 (2022): 7161. DOI:10.3390/molecules27217161
BISINDOLYLMALEIMIDE VII Preparation Products And Raw materials
Raw materials
Preparation Products
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137592-47-3, BISINDOLYLMALEIMIDE VIIRelated Search:
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Bisindolylmaleimide VIII acetate salt
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BISINDOLYLMALEIMIDE II
GANGLIOSIDE GD1A DISODIUM SALT
2,2',3,3',4,4'-hexahydroxy-1,1'-biphenyl-6,6'-dimethanol dimethyl ether
3,4-Di-1H-indol-3-yl-1H-pyrrole-2,5-dione
Bisindolylmaleimide V
BISINDOLYLMALEIMIDE VII
[1-(3-DIMETHYLAMINO-PROPYL)INDOL-3-YL]ACETAMIDE
3-Isopropenyl-1-methyl-1H-pyrrole