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BISINDOLYLMALEIMIDE VII

Product Name
BISINDOLYLMALEIMIDE VII
CAS No.
137592-47-3
Chemical Name
BISINDOLYLMALEIMIDE VII
Synonyms
BISINDOLYLMALEIMIDE VII;1H-Pyrrole-2,5-dione, 3-(1H-indol-3-yl)-4-[1-[3-(1-piperazinyl)propyl]-1H-indol-3-yl]-
CBNumber
CB2246763
Molecular Formula
C27H27N5O2
Formula Weight
453.54
MOL File
137592-47-3.mol
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BISINDOLYLMALEIMIDE VII Property

Boiling point:
761.6±60.0 °C(Predicted)
Density 
1.39±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO: soluble
form 
solid
pka
8.18±0.60(Predicted)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B3681
Product name
Bisindolylmaleimide VII
Purity
96% (TLC), solid
Packaging
1mg
Price
$125
Updated
2025/07/31
American Custom Chemicals Corporation
Product number
PRK0000426
Product name
BISINDOLYLMALEIMIDE VII
Purity
95.00%
Packaging
1MG
Price
$171.15
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PRK0000426
Product name
BISINDOLYLMALEIMIDE VII
Purity
95.00%
Packaging
5MG
Price
$496.72
Updated
2021/12/16
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BISINDOLYLMALEIMIDE VII Chemical Properties,Usage,Production

Uses

Bisindolylmaleimide VII is a potent inhibitor of calmodulin with high affinity for calmodulin (Kd=186.2 nM). Bisindolylmaleimide VII is used to study the role of calmodulin in cancer, neurodegenerative diseases, and muscle dysfunction[1].

Biological Activity

Selective inhibitor of protein kinase C.

References

[1] Sosa-Peinado, et al. Bisindolylmaleimides new ligands of CaM Protein. Molecules 27.21 (2022): 7161. DOI:10.3390/molecules27217161

BISINDOLYLMALEIMIDE VII Preparation Products And Raw materials

Raw materials

Preparation Products

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BISINDOLYLMALEIMIDE VII Suppliers

SIGMA-RBI
Tel
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Fax
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Country
Switzerland
ProdList
6896
Advantage
91
AXXORA, LLC
Tel
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Fax
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Email
alexis-ch@alexis-corp.com
Country
Switzerland
ProdList
1104
Advantage
80
Alexis Corporation
Tel
--
Fax
--
Email
alexis-ch@alexis-corp.ch
Country
Switzerland
ProdList
3599
Advantage
74

137592-47-3, BISINDOLYLMALEIMIDE VIIRelated Search:


  • BISINDOLYLMALEIMIDE VII
  • 1H-Pyrrole-2,5-dione, 3-(1H-indol-3-yl)-4-[1-[3-(1-piperazinyl)propyl]-1H-indol-3-yl]-
  • 137592-47-3
  • C27H27N5O2
  • Kinase/Phosphatase Biology
  • Protein Kinase C (PKC)
  • Serine/Threonine Kinase Inhibitors
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Enzyme Inhibitors by Enzyme
  • Kinase/Phosphatase Biology
  • P to
  • Protein Kinase C (PKC)Cell Signaling and Neuroscience
  • Protein kinase CSerine/Threonine Kinase Biology
  • Protein Kinase Inhibitors
  • Protein Kinase InhibitorsPeptides for Cell Biology
  • Protein Kinase Related Peptides
  • Serine/Threonine Kinase Inhibitors