Tetrahydro-4H-pyran-4-one

Description Application

Product Name: Tetrahydro-4H-pyran-4-one
CAS No.: 29943-42-8
Chemical Name: Tetrahydro-4H-pyran-4-one
Synonyms: dihydro-2H-pyran-4(3H)-one;Oxan-4-one;TETRAHYDROPYRAN-4-ONE;4-THP;4-OXOTETRAHYDROPYRAN;4H-Pyran-4-one, tetrahydro-;EOS-60523;1KG,10KG,25KG;TETRAHYDRO-GAMM;4-Oxacyclohexanone
CBNumber: CB3703050
Molecular Formula: C5H8O2
Formula Weight: 100.12
MOL File: 29943-42-8.mol

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Tetrahydro-4H-pyran-4-one Property

Boiling point:: 166-166.5 °C (lit.)
Density: 1.084 g/mL at 25 °C (lit.)
refractive index: n20/D 1.452(lit.)
Flash point:: 134 °F
storage temp.: Inert atmosphere,Room Temperature
form: Liquid
color: Clear colorless to pale yellow
Water Solubility: MISCIBLE
BRN: 106463
InChIKey: JMJRYTGVHCAYCT-UHFFFAOYSA-N
CAS DataBase Reference: 29943-42-8(CAS DataBase Reference)
NIST Chemistry Reference: 4H-Pyran-4-one, tetrahydro-(29943-42-8)

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Safety

Hazard Codes: Xi,F
Risk Statements: 10-36/37/38
Safety Statements: 24/25-36-26
RIDADR: UN 1224 3/PG 3
WGK Germany: 3
F: 10
Hazard Note: Keep Cold/Flammable/Irritant
HazardClass: 3.2
PackingGroup: III
HS Code: 29329995

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H226Flammable liquid and vapour
Precautionary statements: P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 198242
Product name: Tetrahydro-4H-pyran-4-one
Purity: 99%
Packaging: 1g
Price: $41.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: 198242
Product name: Tetrahydro-4H-pyran-4-one
Purity: 99%
Packaging: 5g
Price: $135
Updated: 2024/03/01

TCI Chemical

Product number: T1806
Product name: Tetrahydro-4H-pyran-4-one
Purity: >95.0%(GC)
Packaging: 1g
Price: $37
Updated: 2024/03/01

TCI Chemical

Product number: T1806
Product name: Tetrahydro-4H-pyran-4-one
Purity: >95.0%(GC)
Packaging: 5g
Price: $104
Updated: 2024/03/01

Alfa Aesar

Product number: A19010
Product name: Tetrahydro-4H-pyran-4-one
Purity: 98%
Packaging: 1g
Price: $41.65
Updated: 2024/03/01

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Tetrahydro-4H-pyran-4-one Chemical Properties,Usage,Production

Description

Tetrahydro-4H-pyran-4-one is used in organic synthesis as building block for more complex chemical structures because it participate in a variety of cycloaddition reactions. Tetrahydro-4H-pyran-4-one is employed in the preparation of 4-methoxytetrahydropyran-4-yl protecting group, synthesis of symmetric tetra substituted methanes.
The methyl enol ether is a useful protecting agent for alcohols, e.g. in nucleotide synthesis, with the advantage over 3,4-Dihydro-2H-pyran. Tetrahydro-4H-pyran-4-one is also employed in a study of the enantioselective alpha-aminoxylation of ketones with nitrosobenzene and L-proline in an ionic liquid. It undergoes condensation reactions in the preparation of dipeptides and spiroimidazolones. Tetrahydro-4H-pyran-4-one is also employed in wittig reactions for the synthesis of Penicillins and in a ring of vitamin D3.

Application

Tetrahydro-4-pyrone is used in organic synthesis as a building block for more complex chemical structures because it participates in a variety of cycloaddition reactions. Tetrahydro-4H-pyran-4-one is employed in a study of the enantioselective alpha-aminoxylation of ketones with nitrosobenzene and L-proline in an ionic liquid and it undergoes condensation reactions in the preparation of dipeptides and spiroimidazolones. Tetrahydro-4H-pyran-4-one is also employed in wittig reactions for the synthesis of penicillins and in a ring of vitamin D3. Additionally, tetrahydro-4-pyrone is used as solvents in some reactions.

Chemical Properties

colorless to light yellow liquid

Uses

Tetrahydro-4-pyrone is used in organic synthesis as building block for more complex chemical structures because it participate in a variety of cycloaddition reactions.

Purification Methods

Purify the pyrone by repeated distillation, preferably in a vacuum. [Baker J Chem Soc 296 1944, IR: Olsen & Bredoch Chem Ber 91 1589 1958.] The oxime has m 87-88o and b 110-111o/13mm [Cornubert et al. Bull Soc Chim Fr 36 1950]. The 4-nitrophenylhydrazone forms orange-brown needles from EtOH, m 186o [Cawley & Plant J Chem Soc 1214 1938]. [Beilstein 17 I 131, 17 II 287, 17 III/IV 4171, 17/9 V 21.]

Tetrahydro-4H-pyran-4-one Preparation Products And Raw materials

Raw materials

Preparation Products

4-Aminotetrahydropyran hydrochloride 4-Aminotetrahydropyran 2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL E-4-Hexen-1-ol

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Tetrahydro-4H-pyran-4-one Suppliers

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View Lastest Price from Tetrahydro-4H-pyran-4-one manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Tetrahydro-4H-pyran-4-one 29943-42-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%min
Supply Ability: 30tons/month
Release date: 2023-02-22

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Tetrahydro-4H-pyran-4-one 29943-42-8
Price: US $65.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg/week
Release date: 2024-06-07

Hebei Chuanghai Biotechnology Co., Ltd

Product: Tetrahydro-4H-pyran-4-one 29943-42-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2025-03-10

29943-42-8, Tetrahydro-4H-pyran-4-oneRelated Search:

Tetrahydropyran Tetrahydrothiophen-3-one 4-Aminotetrahydropyran Centchroman Tetrahydro-4-pyranol 5-Formylsalicylic acid TETRAHYDRO-2H-PYRAN-4-YLACETYL CHLORIDE TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE Tetrahydrothiopyran-4-one Tetrahydro-2H-pyran-4-carboxylic acid Tetrahydropyranyl-4-acetic acid Tetrahydro-4H-Pyran-4-one TETRAHYDROPYRAN-2-METHANOL Ethyl Tetrahydropyran-4-Carboxylate ETHYL TETRAHYDROPYRAN-4-YL-ACETATE (TETRAHYDRO-FURAN-3-YL)-ACETIC ACID Tetrahydropyran-4-carbaldehyde Tetrahydro-2H-pyran-4-carbonyl chloride

Tetrahydro-4-pyrone

TETRAHYDRO-GAMMA-PYRONE

TETRAHYDROPYRAN-4-ONE

TETRAHYDRO-4H-PYRAN-4-ONE

TETRAHYDRO-2H-PYRAN-4-ONE

TetrahydroHpyranone

4-OXOTETRAHYDROPYRAN

4-THP

Tetrahydropyran-4-on

Tetrahydro-4H-pyran-4-one,98%

Tetrahydo-4H-pyran-4-one

4H-Pyran-4-one, tetrahydro-

Tetrahydro-4H-pyran-4-one 97%

Tetranydropyran-4-one

Tetrahydro-4-H-prran-one

Tetrahydro-4H-pran-4-one

Tetrahydro-4H-pyran-4-one, 97+%

Four hydrogen pyran - 4 - ketone

Tetrahydro-4<i>H</i>-pyran-4-one

4-tetrahydropyranone

EOS-60523

TETRAHYDRO-GAMM

1KG,10KG,25KG

2,3,5,6-Tetrahydropyran-4-one

3,5,6-Trihydro-2H-pyran-4-one

Oxan-4-one

4-Oxotetrahydopyran

2,3,5,6-Tetrahydro-4H-pyran-4-one

2,3,5,6-Tetrahydro-4-pyranone

4-Oxacyclohexanone

Tetrahydro-4-pyranone

Tetrahydro-4H-pyran-4-one,99%

dihydro-2H-pyran-4(3H)-one

Tetrahydro-4H-pyran-4-one,4-Oxotetrahydropyran

Tetrahydro-4H-pyran-

4-Oxotetrahydropyran(Tetrahydropyran-4-one)

etrahydro-4H-pyran-4-one

Tetrahydro-4H-pyran-4-one, 99% 5GR

TETRAHYDRO-4H-PYRAN-4-ONE FOR SYNTHESIS

4-Oxotrtrahydropyran

4-Oxotetrahydro-4H-pyran

Tetrahydro-4H-Pyran-4-One (4-THP)

Tetrahydro-4H-pyran-4-one, 98%, for synthesis

Tetrahydro-4H-pyran-4-one ISO 9001：2015 REACH

Tetrahydropyranone

3,4-Dihydro-2H-pyran-2-one

29943-42-8

C5H8O2

KETONE

Building Blocks

Heterocyclic Building Blocks

Pyrans

blocks

Oxygen cyclic compounds

Pyrans, Piperidines &Piperazines

Carbonyl Compounds

Ketone

Pyrans, Piperidines & Piperazines