Uses
ChemicalBook > CAS DataBase List > 2-BROMO-3-FORMYLPYRIDINE

2-BROMO-3-FORMYLPYRIDINE

Uses
Product Name
2-BROMO-3-FORMYLPYRIDINE
CAS No.
128071-75-0
Chemical Name
2-BROMO-3-FORMYLPYRIDINE
Synonyms
2-BROMONICOTINALDEHYDE;CAS:128071-75-0;2-Bromopyridine-3-ca;2-BROMO-3-FORMYLPYRIDINE;2-Bromonicotinaldehyde 97%;2-Bromonicotinaldehyde >2-broMopyridin-3-carbaldehyde;-Bromopyridine-3-carbaldehyde;2-bromopyridine-3-formaldehyde;2-Bromo-3-pyridinecarbaldehyde
CBNumber
CB3710744
Molecular Formula
C6H4BrNO
Formula Weight
186.01
MOL File
128071-75-0.mol
More
Less

2-BROMO-3-FORMYLPYRIDINE Property

Melting point:
73 °C
Boiling point:
100 °C / 3mmHg
Density 
1.683±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
powder to crystal
pka
-1.01±0.10(Predicted)
color 
White to Orange to Green
InChI
InChI=1S/C6H4BrNO/c7-6-5(4-9)2-1-3-8-6/h1-4H
InChIKey
GNFWMEFWZWXLIN-UHFFFAOYSA-N
SMILES
C1(Br)=NC=CC=C1C=O
CAS DataBase Reference
128071-75-0(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36-43
Safety Statements 
26-36/37
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29333990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
632147
Product name
2-Bromo-3-pyridinecarboxaldehyde
Purity
96%
Packaging
1g
Price
$26.8
Updated
2025/07/31
Sigma-Aldrich
Product number
632147
Product name
2-Bromo-3-pyridinecarboxaldehyde
Purity
96%
Packaging
5g
Price
$37.62
Updated
2025/07/31
TCI Chemical
Product number
B2625
Product name
2-Bromonicotinaldehyde
Purity
>98.0%(GC)
Packaging
1g
Price
$32
Updated
2025/07/31
TCI Chemical
Product number
B2625
Product name
2-Bromonicotinaldehyde
Purity
>98.0%(GC)
Packaging
5g
Price
$106
Updated
2025/07/31
TRC
Product number
B677835
Product name
2-Bromonicotinaldehyde
Packaging
10mg
Price
$45
Updated
2021/12/16
More
Less

2-BROMO-3-FORMYLPYRIDINE Chemical Properties,Usage,Production

Uses

2-Bromo-3-pyridinecarboxaldehyde is a pyridine heterocyclic compound mainly used in laboratory organic synthesis processes.

Chemical Properties

Yellow solid

Synthesis

109-04-6

68-12-2

128071-75-0

To a cooled solution of diisopropylamine (20.4 g, 28.0 mL, 0.202 mol) in anhydrous THF (400 mL) at -78 °C was slowly added n-BuLi (0.192 mol, 58.0 mL, 3.3 M hexane solution). The reaction mixture was stirred at -78 °C for 1 h, followed by the dropwise addition of anhydrous THF (150 mL) solution of 2-bromopyridine (25.3 g, 0.160 mol) over 20 min. After keeping the reaction at -78 °C for 90 min, an anhydrous THF (25 mL) solution of DMF (35.0 g, 0.480 mol) cooled to -78 °C was quickly added. Stirring was continued at -78 °C for 80 min, and upon completion of the reaction, the reaction was quenched with NaH2PO4 (27.6 g, 0.230 mol, dissolved in H2O (120 mL)), slowly warmed to room temperature, and diluted with MeOt-Bu (500 mL). The organic phase was separated, washed with brine (2100 mL), dried over anhydrous Na2SO4 and concentrated under reduced pressure. The crude product was ground with pentane and after decantation, the remaining solid was recrystallized from hexane to give 16.7 g of 2-bromo-3-pyridinecarboxaldehyde as a pale yellow solid in 56% yield, melting point 67-69 °C. 1H NMR (400 MHz, CDCl3) δ: 10.35 (s, 1H), 8.57 (dd, J=4.7,2.1 Hz, 1H), 8.17 (dd, J= 7.6,2.1Hz, 1H), 7.44 (dd, J=7.6,4.7,0.6Hz, 1H).13C NMR (101MHz, CDCl3) δ: 190.4,154.0,144.9,137.5,130.1,123.0. Calculated values for elemental analyses (C6H4BrNO): C, 38.74; H. 2.17; N, 7.53; Br, 42.96. Measured values: C, 38.58; H, 2.08; N, 7.57; Br, 42.69.

References

[1] Tetrahedron Letters, 2008, vol. 49, # 17, p. 2839 - 2843
[2] Chemical Communications, 2011, vol. 47, # 23, p. 6635 - 6637
[3] Organic Letters, 2007, vol. 9, # 5, p. 891 - 894
[4] Tetrahedron Letters, 2017, vol. 58, # 20, p. 1989 - 1991
[5] Synthesis (Germany), 2018, vol. 50, # 1, p. 155 - 169

2-BROMO-3-FORMYLPYRIDINE Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide 2-Bromopyridine Sodium borohydride Tetrahydrofuran Ammonium chloride Isopropylamine n-Butyllithium

Preparation Products

More
Less

2-BROMO-3-FORMYLPYRIDINE Suppliers

Americas 1 Belgium 2 Canada 1 China 187 Europe 1 France 2 Germany 4 India 11 Japan 1 Russia 1 Slovakia 1 Switzerland 1 The Netherlands 1 Ukraine 1 United Kingdom 10 United States 46 Global 271
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
AbaChemScene
Tel
732-484-9848
Fax
888-484-5008
Email
sales@chemscene.com
Country
United States
ProdList
3982
Advantage
60
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
21193
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Aceschem Inc.
Tel
+1-817863-6948 +1-（817）863-6948
Email
sales@aceschem.com
Country
United States
ProdList
19632
Advantage
58
Alfa Chemistry
Tel
Email
info@alfa-chemistry.com
Country
United States
ProdList
2344
Advantage
58
Aston Chemical
Tel
13000000000
Email
sales@astonchem.com
Country
United States
ProdList
1634
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
SV ChemBioTech, Inc.
Tel
--
Fax
--
Email
sales@svchembiotech.com
Country
United States
ProdList
102
Advantage
50
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United States
ProdList
4583
Advantage
58
TCI America, Inc. (Tokyo Chemical Industry Co., Ltd.)
Tel
--
Fax
--
Email
.Crew@tcichemicals.com
Country
United States
ProdList
3164
Advantage
58
Crescent Chemical Company
Tel
--
Fax
--
Email
fran@creschem.com
Country
United States
ProdList
1441
Advantage
58
Parchem Fine & Specialty Chemicals
Tel
--
Fax
--
Email
info@parchem.com
Country
United States
ProdList
1031
Advantage
58
MilliporeSigma (Sigma-Aldrich Corp.)
Tel
--
Fax
--
Email
@sial.com
Country
United States
ProdList
5414
Advantage
58
eNovation Chemicals LLC
Tel
--
Fax
--
Email
ales@eNovationChem.com
Country
United States
ProdList
1673
Advantage
58
Combi-Blocks, Inc.
Tel
--
Fax
--
Email
les@combi-blocks.com
Country
United States
ProdList
2555
Advantage
58
AOBChem
Tel
--
Fax
--
Email
sales@aobchem.com
Country
United States
ProdList
885
Advantage
58
SynQuest Laboratories, Inc. (Part of Central Glass Co., Ltd.)
Tel
--
Fax
--
Email
nfo@synquestlabs.com
Country
United States
ProdList
1897
Advantage
58
Frontier Scientific, Inc. (FSI)
Tel
--
Fax
--
Country
United States
ProdList
159
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
Tyger Scientific Inc.
Tel
--
Fax
--
Email
sales@tygersci.com
Country
United States
ProdList
402
Advantage
58
2A Biotech USA
Tel
--
Fax
--
Email
info@2abiotech.com
Country
United States
ProdList
1785
Advantage
58
Advanced Chemical Intermediates Ltd.
Tel
--
Fax
--
Email
enquiries@acints.com
Country
United States
ProdList
4893
Advantage
58
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
Spectrum Chemical Mfg. Corp.
Tel
--
Fax
--
Email
marketing@spectrumchemical.com
Country
United States
ProdList
3113
Advantage
60
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Anvia Chemicals, LLC
Tel
--
Fax
--
Email
sales@anviachem.com
Country
United States
ProdList
3933
Advantage
0
AOBChem USA
Tel
--
Fax
--
Email
sales@aobchem.com
Country
United States
ProdList
3487
Advantage
50
Angene International Limited
Tel
--
Fax
--
Email
sales@angenechemical.com
Country
United States
ProdList
100
Advantage
50
Wilshire Chemical Company Inc.
Tel
--
Fax
--
Email
WilshrChem@AOL.COM
Country
United States
ProdList
3498
Advantage
58
Aagile Labs Division of Tyger Scientific
Tel
--
Fax
--
Email
tygersci@yahoo.com
Country
United States
ProdList
6568
Advantage
68
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Anthem Pharmaceutical Research LLC
Tel
--
Fax
--
Email
sales@anthempharma.com
Country
United States
ProdList
3040
Advantage
30
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
INDOFINE Chemical Company, Inc.
Tel
--
Fax
--
Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
Advantage
69
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
Advantage
38
Anichem LLC
Tel
--
Fax
--
Email
sales@anichemllc.com
Country
United States
ProdList
4112
Advantage
34
More
Less

View Lastest Price from 2-BROMO-3-FORMYLPYRIDINE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-BROMO-3-FORMYLPYRIDINE 128071-75-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-06-03
Henan Aochuang Chemical Co.,Ltd.
Product
2-BROMO-3-FORMYLPYRIDINE 128071-75-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-13
Henan Fengda Chemical Co., Ltd
Product
2-BROMO-3-FORMYLPYRIDINE 128071-75-0
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08

128071-75-0, 2-BROMO-3-FORMYLPYRIDINERelated Search:

2-BROMO-5-NITRONICOTINIC ACID 2-BROMONICOTINAMIDE 3-Acetyl-2-bromopyridine 2-BROMO-6-TRUFLUOROMETHYL-3-PYRIDINECARBOXYLIC ACID 2-BROMO-3-FORMYLPYRIDINE 2-Bromonicotinic acid 2,5-DIBROMONICOTINIC ACID 2-Bromo-5-chloronicotinic acid 2-BROMONICOTINIC ACID ETHYL ESTER 2,5-DIBROMONICOTINALDEHYDE 3,5-Dibromopyridine-4-carboxaldehyde 6-BROMO-2-FORMYLPYRIDINE,2-BROMO-6-FORMYLPYRIDINE 5-BROMO-2-FORMYLPYRIDINE,2-FORMYL-5-BROMOPYRIDINE / 5-BROMO-2-FORMYLPYRIDINE,5-Bromo-2-formylpyridine, 5-Bromo-2-picolinaldehyde 2-BROMO-4-FORMYLPYRIDINE 3-BROMO-4-FORMYLPYRIDINE 2-BROMO-5-FORMYLPYRIDINE,2-BROMO-5-FORMYLPYRIDINE97+% ,5-Dihydro-5-methyl-6-[4-(4-oxo-1(4H)-pyridinyl)phenyl]-1,2,4-triazin-3(2H)-one 5-Bromo-3-formylpyridine

  • 2-BROMONICOTINALDEHYDE
  • 2-BROMO-PYRIDINE-3-CARBALDEHYDE
  • 2-BROMOPYRIDINE-3-CARBOXALDEHYDE
  • 2-BROMO-3-FORMYLPYRIDINE
  • 2-BROMO-3-PYRIDINECARBOXALDEHYDE
  • 2-Bromo-3-pyridinecarboxaldehyde ,96%
  • 2-Bromopyridine-3-carboxaldehyde 97%
  • 2-Bromopyridine-3-carboxaldehyde, 2-Bromo-3-formylpyridine
  • 2-Bromo-3-pyridinecarboxaldehyde,2-Bromo-3-formylpyridine
  • 2-Bromonicotinaldehyde 97%
  • 2-bromonicotinaldehyde(SALTDATA: FREE)
  • 2-broMopyridin-3-carbaldehyde
  • 2-Bromo-3-pyridinecarboxaldehyde 96%
  • 2-Bromopyridine-3-ca
  • 2-Bromonicotinaldehyde &gt
  • 3-Pyridinecarboxaldehyde, 2-bromo-
  • 2-BROMO-3-FORMYLPYRIDINE ISO 9001：2015 REACH
  • -Bromopyridine-3-carbaldehyde
  • 2-bromopyridine-3-formaldehyde
  • 2-Bromo-3-pyridinecarbaldehyde
  • CAS:128071-75-0
  • 128071-75-0
  • Halogenated Heterocycles
  • Bromopyridines
  • Halopyridines
  • Pyridines
  • Heterocyclic Building Blocks
  • Building Blocks
  • Heterocycle-Pyridine series
  • Heterocycles
  • Halogenated
  • Organohalides
  • Bromopyridines
  • Halopyridines
  • pharmacetical
  • Aldehydes
  • Pyridines
  • Pyridine
  • Pyridines derivates