4-Iodoaniline

Product Name: 4-Iodoaniline
CAS No.: 540-37-4
Chemical Name: 4-Iodoaniline
Synonyms: BENZENAMINE, 4-IODO-;P-IODOANILINE;4-iodobenzenamine;4-IodoaniL;4-LODANILINE;4-IODOANILINE;4-iodo-anilin;p-iodo-anilin;p－lodoaniline;Iodine aniline
CBNumber: CB5110557
Molecular Formula: C6H6IN
Formula Weight: 219.02
MOL File: 540-37-4.mol

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4-Iodoaniline Property

Melting point:: 61-63 °C(lit.)
Boiling point:: 268.7±23.0 °C(Predicted)
Density: 1.8155 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: H2O: slightly soluble
form: Crystalline Powder or Needles
pka: 3.81(at 25℃)
color: Beige to grayish-brown
Water Solubility: Slightly soluble in water.Soluble in chloroform, methanol.
Sensitive: Light Sensitive
Merck: 14,5027
BRN: 774101
InChIKey: VLVCDUSVTXIWGW-UHFFFAOYSA-N
CAS DataBase Reference: 540-37-4(CAS DataBase Reference)
NIST Chemistry Reference: Benzenamine, 4-iodo-(540-37-4)
EPA Substance Registry System: Benzenamine, 4-iodo- (540-37-4)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38-20/21/22
Safety Statements: 26-36/37/39-36
RIDADR: 2811
WGK Germany: 3
RTECS: BY3850000
F: 8
Hazard Note: Harmful/Irritant
TSCA: T
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 29214210

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 129364
Product name: 4-Iodoaniline
Purity: 98%
Packaging: 25g
Price: $59
Updated: 2024/03/01

Sigma-Aldrich

Product number: 129364
Product name: 4-Iodoaniline
Purity: 98%
Packaging: 100g
Price: $73.6
Updated: 2024/03/01

TCI Chemical

Product number: I0048
Product name: 4-Iodoaniline
Packaging: 25G
Price: $68
Updated: 2024/03/01

TCI Chemical

Product number: I0048
Product name: 4-Iodoaniline
Packaging: 250G
Price: $215
Updated: 2022/04/27

Alfa Aesar

Product number: B21936
Product name: 4-Iodoaniline, 98%
Packaging: 50g
Price: $73.9
Updated: 2024/03/01

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4-Iodoaniline Chemical Properties,Usage,Production

Chemical Properties

beige to greyish-brown crystalline powder. soluble in alcohol, ether and chloroform, slightly soluble in water.

Uses

suzuki reaction

Uses

4-dehydroanilinium ion, a stable distonic isomer of ionized aniline, by collision-activated dissociation of protonated 4-iodoaniline. Palladium-catalyzed carbonylation of 4-iodoaniline gave the corresponding four- armed star polybenzamides. 4-Iodoaniline is a iodine substituted aniline that is widely used as chemical intermediates in the manufacturing of dyes and drugs. 4-Iodoaniline was used to prepare phenyl functionalized graphene oxide (I-Ph-GO).

Uses

4-Iodoaniline is a iodine substituted aniline that is widely used as chemical intermediates in the manufacturing of pesticides, dyes and drugs. 4-Iodoaniline was shown to be a more potent nephrotoxica nt in vitro than other anilines.

Preparation

4-Iodoaniline is obtained by the reaction of aniline and iodine in the presence of sodium bicarbonate. Add aniline and sodium bicarbonate to water and slowly add crushed iodine in stages with vigorous stirring. If the reaction solution is yellow, add a little sodium bisulfite to make it discolor, then filter and get the crude product. Then the product is recrystallized by ethanol to obtain 4-Iodoaniline.

General Description

4-Iodoaniline is the most potent methaemoglobin former.

Purification Methods

Crystallise it from pet ether (b 60-80o) by refluxing, then cool it in an ice-salt bath freezing mixture. Dry it in air. Alternatively, crystallise it from EtOH and dry it in vacuo for 6hours at 40o [Edidin et al. J Am Chem Soc 109 3945 1987]. The N-acetyl derivative has m 184o (from MeOH). [Beilstein 12 IV 1544.]

4-Iodoaniline Preparation Products And Raw materials

Raw materials

Sodium bisulfite

Preparation Products

4-ETHYNYLANILINE N-(4-THIOPHEN-2-YL-PHENYL)-ACETAMIDE

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4-Iodoaniline Suppliers

Americas 1 Austria 1 Belgium 2 Canada 1 China 390 Europe 3 Germany 13 India 52 Japan 6 Poland 1 Slovakia 1 Switzerland 3 Ukraine 2 United Kingdom 22 United States 54 Global 553

INTATRADE GmbH

Tel: +49 3493/605464
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ORGANICA Feinchemie GmbH

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Merck Millipore

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Service Chemical Inc.

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EMKA-Chemie Organische Feinchemikalien

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Merck Schuchardt OHG

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View Lastest Price from 4-Iodoaniline manufacturers

Hubei Lidu New Material Technology Co., Ltd

Product: 4-IODOANILINE 540-37-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2024-10-30

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 4-Iodoaniline 540-37-4
Price: US $75.00-20.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-06-03

Hebei Weibang Biotechnology Co., Ltd

Product: 4-Iodoaniline 540-37-4
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-08

540-37-4, 4-IodoanilineRelated Search:

3-Aminophenol ALTRENOGEST Iodobenzene p-Toluidine Benzidine 2-Iodoaniline Glycine 4-Chloroaniline N,N-Dimethyl-1,4-phenylenediamine 6-Aminocaproic acid Tris(hydroxymethyl)aminomethane 4-Fluoroaniline Phenetidine Aniline 4'-Nitroacetanilide p-Anisidine 4-Aminobenzonitrile p-Aminobenzamide

BENZENAMINE, 4-IODO-

1-amino-4-iodobenzene

4-IODOANILINE

4-LODANILINE

P-IODOANILINE

4-iodo-anilin

4-iodo-benzenamin

4-iodobenzenamine

4-iodo-Benzenamine

p－lodoaniline

1-Iodo-4-aminobenzene

p-Aminoiodobenzene

4-Aminophenyl iodide

4-Iodoaniline,99%

4-IodobenzeneaMine

4-Iodoaniline, 99% 25GR

The iodine aniline

Iodine aniline

4-Iodoaniline≥ 98% (GC)

4-IodoaniL

4-Iodo-phenylamine

Aniline, 4-iodo-

Aniline, p-iodo-

Benzenamine,4-Iodoaniline

p-Aminophenyl iodide

p-aminophenyliodide

p-iodo-anilin

4-Indo Aniline

IODOANILINE, 4-

4-Iodoaniline,~98%

4-Iodoaniline, 98%, for synthesis

4-Iodoaniline&gt

4 - iodine aniline

4-Iodoaniline ISO 9001：2015 REACH

RSYY(Apremilast)-8

4 Iodoaniline (P-Iodoaniline,4-Iodobenzenamine)

4-iodoaniline (4-iodoaniline)

540-37-4

IC6H4NH2

IC6H6N

C2 to C6

Building Blocks

Amines

AMINE

Organic Building Blocks

Nitrogen Compounds

Building Blocks

C6

Chemical Synthesis

Nitrogen Compounds

Organic Building Blocks

Pharmaceutical Intermediates

Anilines, Aromatic Amines and Nitro Compounds

Amines

API intermediates

Anilines, Amides & Amines

Iodine Compounds

C2 to C6