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4-Iodoaniline

Product Name
4-Iodoaniline
CAS No.
540-37-4
Chemical Name
4-Iodoaniline
Synonyms
BENZENAMINE, 4-IODO-;P-IODOANILINE;4-iodobenzenamine;4-IodoaniL;4-LODANILINE;4-IODOANILINE;4-iodo-anilin;p-iodo-anilin;p-lodoaniline;Iodine aniline
CBNumber
CB5110557
Molecular Formula
C6H6IN
Formula Weight
219.02
MOL File
540-37-4.mol
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4-Iodoaniline Property

Melting point:
61-63 °C(lit.)
Boiling point:
268.7±23.0 °C(Predicted)
Density 
1.8155 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
H2O: slightly soluble
form 
Crystalline Powder or Needles
pka
3.81(at 25℃)
color 
Beige to grayish-brown
Water Solubility 
Slightly soluble in water.Soluble in chloroform, methanol.
Sensitive 
Light Sensitive
Merck 
14,5027
BRN 
774101
InChIKey
VLVCDUSVTXIWGW-UHFFFAOYSA-N
CAS DataBase Reference
540-37-4(CAS DataBase Reference)
NIST Chemistry Reference
Benzenamine, 4-iodo-(540-37-4)
EPA Substance Registry System
Benzenamine, 4-iodo- (540-37-4)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38-20/21/22
Safety Statements 
26-36/37/39-36
RIDADR 
2811
WGK Germany 
3
RTECS 
BY3850000
8
Hazard Note 
Harmful/Irritant
TSCA 
T
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29214210
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
129364
Product name
4-Iodoaniline
Purity
98%
Packaging
25g
Price
$59
Updated
2024/03/01
Sigma-Aldrich
Product number
129364
Product name
4-Iodoaniline
Purity
98%
Packaging
100g
Price
$73.6
Updated
2024/03/01
TCI Chemical
Product number
I0048
Product name
4-Iodoaniline
Packaging
25G
Price
$68
Updated
2024/03/01
TCI Chemical
Product number
I0048
Product name
4-Iodoaniline
Packaging
250G
Price
$215
Updated
2022/04/27
Alfa Aesar
Product number
B21936
Product name
4-Iodoaniline, 98%
Packaging
50g
Price
$73.9
Updated
2024/03/01
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4-Iodoaniline Chemical Properties,Usage,Production

Chemical Properties

beige to greyish-brown crystalline powder. soluble in alcohol, ether and chloroform, slightly soluble in water.

Uses

suzuki reaction

Uses

4-dehydroanilinium ion, a stable distonic isomer of ionized aniline, by collision-activated dissociation of protonated 4-iodoaniline. Palladium-catalyzed carbonylation of 4-iodoaniline gave the corresponding four- armed star polybenzamides. 4-Iodoaniline is a iodine substituted aniline that is widely used as chemical intermediates in the manufacturing of dyes and drugs. 4-Iodoaniline was used to prepare phenyl functionalized graphene oxide (I-Ph-GO).

Uses

4-Iodoaniline is a iodine substituted aniline that is widely used as chemical intermediates in the manufacturing of pesticides, dyes and drugs. 4-Iodoaniline was shown to be a more potent nephrotoxica nt in vitro than other anilines.

Preparation

4-Iodoaniline is obtained by the reaction of aniline and iodine in the presence of sodium bicarbonate. Add aniline and sodium bicarbonate to water and slowly add crushed iodine in stages with vigorous stirring. If the reaction solution is yellow, add a little sodium bisulfite to make it discolor, then filter and get the crude product. Then the product is recrystallized by ethanol to obtain 4-Iodoaniline.

General Description

4-Iodoaniline is the most potent methaemoglobin former.

Purification Methods

Crystallise it from pet ether (b 60-80o) by refluxing, then cool it in an ice-salt bath freezing mixture. Dry it in air. Alternatively, crystallise it from EtOH and dry it in vacuo for 6hours at 40o [Edidin et al. J Am Chem Soc 109 3945 1987]. The N-acetyl derivative has m 184o (from MeOH). [Beilstein 12 IV 1544.]

4-Iodoaniline Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Iodoaniline Suppliers

UkrOrgSynthesis Ltd.
Tel
--
Fax
--
Email
y.barysheva@ukrorgsynth.com
Country
Ukraine
ProdList
6230
Advantage
38
CAS Organic Company
Tel
--
Fax
--
Email
Sales@casorganic.com
Country
Ukraine
ProdList
5026
Advantage
34
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View Lastest Price from 4-Iodoaniline manufacturers

Hubei Lidu New Material Technology Co., Ltd
Product
4-IODOANILINE 540-37-4
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2024-10-30
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
4-Iodoaniline 540-37-4
Price
US $75.00-20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-06-03
Hebei Weibang Biotechnology Co., Ltd
Product
4-Iodoaniline 540-37-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-08

540-37-4, 4-IodoanilineRelated Search:


  • BENZENAMINE, 4-IODO-
  • 1-amino-4-iodobenzene
  • 4-IODOANILINE
  • 4-LODANILINE
  • P-IODOANILINE
  • 4-iodo-anilin
  • 4-iodo-benzenamin
  • 4-iodobenzenamine
  • 4-iodo-Benzenamine
  • p-lodoaniline
  • 1-Iodo-4-aminobenzene
  • p-Aminoiodobenzene
  • 4-Aminophenyl iodide
  • 4-Iodoaniline,99%
  • 4-IodobenzeneaMine
  • 4-Iodoaniline, 99% 25GR
  • The iodine aniline
  • Iodine aniline
  • 4-Iodoaniline≥ 98% (GC)
  • 4-IodoaniL
  • 4-Iodo-phenylamine
  • Aniline, 4-iodo-
  • Aniline, p-iodo-
  • Benzenamine,4-Iodoaniline
  • p-Aminophenyl iodide
  • p-aminophenyliodide
  • p-iodo-anilin
  • 4-Indo Aniline
  • IODOANILINE, 4-
  • 4-Iodoaniline,~98%
  • 4-Iodoaniline, 98%, for synthesis
  • 4-Iodoaniline&gt
  • 4 - iodine aniline
  • 4-Iodoaniline ISO 9001:2015 REACH
  • RSYY(Apremilast)-8
  • 4 Iodoaniline (P-Iodoaniline,4-Iodobenzenamine)
  • 4-iodoaniline (4-iodoaniline)
  • 540-37-4
  • IC6H4NH2
  • IC6H6N
  • C2 to C6
  • Building Blocks
  • Amines
  • AMINE
  • Organic Building Blocks
  • Nitrogen Compounds
  • Building Blocks
  • C6
  • Chemical Synthesis
  • Nitrogen Compounds
  • Organic Building Blocks
  • Pharmaceutical Intermediates
  • Anilines, Aromatic Amines and Nitro Compounds
  • Amines
  • API intermediates
  • Anilines, Amides & Amines
  • Iodine Compounds
  • C2 to C6