LY3214996

Product Name: LY3214996
CAS No.: 1951483-29-6
Chemical Name: LY3214996
Synonyms: CS-2495;LY3214996;Temuterkib;Temuterkib (LY3214996);LY-3214996 (LY3214996);LY-3214996,LY 3214996,inhibit,Extracellular signal regulated kinases,Temuterkib,Inhibitor,ERK;6,6-dimethyl-2-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)-5-(2-morpholinoethyl)-5,6-dihydro-4H-thieno[2,3-c]pyrrol-4-one;4H-Thieno[2,3-c]pyrrol-4-one, 5,6-dihydro-6,6-dimethyl-2-[2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl]-5-[2-(4-morpholinyl)ethyl]-
CBNumber: CB53168760
Molecular Formula: C22H27N7O2S
Formula Weight: 453.56
MOL File: 1951483-29-6.mol

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LY3214996 Property

Boiling point:: 711.5±70.0 °C(Predicted)
Density: 1.43±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:23.5(Max Conc. mg/mL);51.81(Max Conc. mM)
Ethanol:16.0(Max Conc. mg/mL);35.28(Max Conc. mM)
form: A crystalline solid
pka: 6.58±0.10(Predicted)
color: White to yellow

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Safety

HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27936
Product name: LY3214996
Packaging: 1mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 27936
Product name: LY3214996
Packaging: 25mg
Price: $1026
Updated: 2024/03/01

Cayman Chemical

Product number: 27936
Product name: LY3214996
Packaging: 5mg
Price: $233
Updated: 2024/03/01

Cayman Chemical

Product number: 27936
Product name: LY3214996
Packaging: 10mg
Price: $437
Updated: 2024/03/01

ChemScene

Product number: CS-6974
Product name: LY3214996
Purity: 99.54%
Packaging: 1mg
Price: $80
Updated: 2021/12/16

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LY3214996 Chemical Properties,Usage,Production

Description

LY3214996 is an inhibitor of ERK1 and ERK2 (IC₅₀ = 5 nM for both). It inhibits cell proliferation of tumor cells in vitro, including those expressing B-RAF, N-Ras, or K-Ras mutations. LY3214996 inhibits tumor growth in B-RAF or N-Ras mutant melanoma, B-RAF or K-Ras mutant colorectal, lung, and pancreatic cancer mouse xenograft models, as well as patient-derived xenograft (PDX) mouse models.

LY3214996 Preparation Products And Raw materials

Raw materials

Preparation Products

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LY3214996 Suppliers

China 65 India 1 United States 7 USA 1 Global 74

MedChemexpress LLC

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1951483-29-6, LY3214996Related Search:

LY-2940094 LY2828360 LY-2562175 LY2228820 Etalocib LY2584702 LY 2784544 LY2409881 trihydrochloride LY-364947 LY 88074 (S)-3-fluoro-4-(4-((2-(3-fluorophenyl)pyrrolidin-1-yl)methyl)phenoxy)benzamide LY-3177833 2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol LY2409881 Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2 LY3023414 LY 294002 HYDROCHLORIDE LY2955303

LY3214996

6,6-dimethyl-2-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)-5-(2-morpholinoethyl)-5,6-dihydro-4H-thieno[2,3-c]pyrrol-4-one

CS-2495

4H-Thieno[2,3-c]pyrrol-4-one, 5,6-dihydro-6,6-dimethyl-2-[2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl]-5-[2-(4-morpholinyl)ethyl]-

Temuterkib

Temuterkib (LY3214996)

LY-3214996,LY 3214996,inhibit,Extracellular signal regulated kinases,Temuterkib,Inhibitor,ERK

LY-3214996 (LY3214996)

1951483-29-6