4,6-Dichloronicotinic acid

Product Name: 4,6-Dichloronicotinic acid
CAS No.: 73027-79-9
Chemical Name: 4,6-Dichloronicotinic acid
Synonyms: 4,6-DichloronicotinicAci;4,6-DICHLORONICOTINIC ACID;2,4-Dichloro-5-carboxypyridine;2,4-DICHLORO-5-CARBOXYLPYRIDINE;4,6-Dichloronicotinic acid ,97%;2,4-Dichloro-5-carboxylpyridine ,97%;4,6-Dichloronicotinic Acid(WX614282);4,6-Dichloropyridin-3-carboxylic acid;2,4-Dichloro-5-pyridinecarboxylic acid;4,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID
CBNumber: CB5449682
Molecular Formula: C6H3Cl2NO2
Formula Weight: 192
MOL File: 73027-79-9.mol

More

Less

4,6-Dichloronicotinic acid Property

Melting point:: 158-160
Boiling point:: 337.0±37.0 °C(Predicted)
Density: 1.612±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 1.87±0.25(Predicted)
form: Solid
color: White to Light yellow
Water Solubility: Slightly soluble in water.
Stability:: Hygroscopic
InChI: InChI=1S/C6H3Cl2NO2/c7-4-1-5(8)9-2-3(4)6(10)11/h1-2H,(H,10,11)
InChIKey: ILMIEWNDXAKVNI-UHFFFAOYSA-N
SMILES: C1=NC(Cl)=CC(Cl)=C1C(O)=O
CAS DataBase Reference: 73027-79-9(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 22-20/21/22
Safety Statements: 24/25-36/37
HazardClass: IRRITANT
HS Code: 29333990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: D5311
Product name: 4,6-Dichloronicotinic Acid
Purity: >98.0%(T)
Packaging: 1g
Price: $30
Updated: 2025/07/31

TCI Chemical

Product number: D5311
Product name: 4,6-Dichloronicotinic Acid
Purity: >98.0%(T)
Packaging: 5g
Price: $118
Updated: 2025/07/31

TRC

Product number: D435638
Product name: 4,6-Dichloronicotinic Acid
Packaging: 1g
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD52890
Product name: 4,6-Dichloronicotinic acid
Packaging: 10g
Price: $75
Updated: 2021/12/16

Oakwood

Product number: 062528
Product name: 4,6-Dichloronicotinic Acid
Purity: 97%
Packaging: 1g
Price: $13
Updated: 2021/12/16

More

Less

4,6-Dichloronicotinic acid Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

4,6-Dichloronicotinic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.

Synthesis

40296-46-6

73027-79-9

General procedure for the synthesis of 4,6-dichloronicotinic acid from ethyl 4,6-dichloronicotinate: to a stirred solution of ethyl 4,6-dichloronicotinate (22) (25.95 g, 118 mmol) dissolved in 4:1:1 THF:MeOH:water (600 mL) was added sodium hydroxide solution (40 mL, 6.25 M). After 30 min of reaction, the reaction mixture was acidified to pH 2 with concentrated hydrochloric acid and subsequently diluted with 1:1 EtOAc:Et2O and washed sequentially with water and brine. The organic layer was dried over anhydrous sodium sulfate and concentrated. The resulting off-white solid was purified by concentrating twice from toluene to give the final target product 4,6-dichloronicotinic acid (23) as a white solid (21.73 g, 96% yield).

References

[1] Patent: US2005/49419, 2005, A1. Location in patent: Page/Page column 24
[2] Patent: US2005/54701, 2005, A1
[3] Tetrahedron Letters, 2011, vol. 52, # 4, p. 512 - 514
[4] Patent: WO2014/52365, 2014, A1. Location in patent: Page/Page column 229-230
[5] Patent: US2015/191464, 2015, A1. Location in patent: Paragraph 0611

4,6-Dichloronicotinic acid Preparation Products And Raw materials

Raw materials

Diethyl 1,3-acetonedicarboxylate Ammonium hydroxide Acetic anhydride Triethyl orthoformate Phosphorus oxitrichloride Hydrochloric acid Sodium hydroxide

Preparation Products

4,6-DICHLORO-PYRIDIN-3-YLAMINE

More

Less

4,6-Dichloronicotinic acid Suppliers

Americas 1 China 251 Europe 2 Germany 3 India 7 Japan 1 The Netherlands 1 United Kingdom 5 United States 25 Global 296

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Accela ChemBio Inc.

Tel: +1(858) 699-3322
Fax: +1(858) 876-1948
Email: marketing@accelachem.com
Country: United States
ProdList: 6024
Advantage: 65

Accela ChemBio Inc.

Tel: +1-858-6993322
Fax: (+1)-858-876-1948
Email: info@accelachem.com
Country: United States
ProdList: 21193
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Protheragen-ING

Tel: +16313385890
Email: info@protheragen-ing.com
Country: United States
ProdList: 3868
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Synthonix Inc

Tel: --
Fax: --
Email: info@synthonix.com
Country: United States
ProdList: 6872
Advantage: 58

Alfa Chemistry

Tel: --
Fax: --
Email: info@Alfa-Chemistry.com
Country: United States
ProdList: 6814
Advantage: 0

SynQuest Laboratories, Inc.

Tel: --
Fax: --
Email: info@synquestlabs.com
Country: United States
ProdList: 6871
Advantage: 62

TCI America

Tel: --
Fax: --
Email: sales@tciamerica.com
Country: United States
ProdList: 6909
Advantage: 75

Frontier Scientific, Inc.

Tel: --
Fax: --
Email: sales@frontiersci.com
Country: United States
ProdList: 6222
Advantage: 86

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

NOVASYN ORGANICS PVT LTD

Tel: --
Fax: --
Email: info@novasynorganics.com
Country: United States
ProdList: 1316
Advantage: 55

Wilshire Chemical Company Inc.

Tel: --
Fax: --
Email: WilshrChem@AOL.COM
Country: United States
ProdList: 3498
Advantage: 58

Rintech, Inc.

Tel: --
Fax: --
Email: info@rintechinc.com
Country: United States
ProdList: 3416
Advantage: 60

AlliChem, LLC

Tel: --
Fax: --
Email: sales@allichemllc.com
Country: United States
ProdList: 6516
Advantage: 60

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Chem-Impex International, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6730
Advantage: 64

Ryan Scientific, Inc.

Tel: --
Fax: --
Email: ryan.reichlyn@ryansci.com
Country: United States
ProdList: 6439
Advantage: 60

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

Allichem LLC

Tel: --
Fax: --
Email: lib@umbi.umd.edu
Country: United States
ProdList: 749
Advantage: 30

ChemPacific Corporation

Tel: --
Fax: --
Email: sales@chempacific.com
Country: United States
ProdList: 6891
Advantage: 51

More

Less

View Lastest Price from 4,6-Dichloronicotinic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 4,6-Dichloronicotinic acid 73027-79-9
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-06-27

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 4,6-Dichloronicotinic acid 73027-79-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-22

Shaanxi Dideu New Materials Co. Ltd

Product: 4,6-Dichloronicotinic acid 73027-79-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-03-10

73027-79-9, 4,6-Dichloronicotinic acidRelated Search:

Clopyralid 6-Chloronicotinic acid 3,4-Dichloropyridine 2',4'-Dichloroacetophenone Zinc picolinate 4-Chloronicotinic acid 2,6-Dichloropyridine 1,2-Dichloro-4-(chloromethyl)benzene Dichloroethane 2,4-Dichlorophenol 2-Picolinic acid 2-Chloro-5-chloromethylpyridine 2-Chloronicotinic acid Thionyl chloride 2,6-Dichloroisonicotinic acid 2,6-Dichloro-5-fluoronicotinic acid Quinclorac 2,5-PYRIDINEDICARBOXYLIC ACID

2,4-DICHLORO-5-PYRIDINE-5-CARBOXYLIC ACID

2,4-DICHLORO-5-CARBOXYLPYRIDINE

2,4-DICHLOROPYRIDINE-5-CARBOXYLIC ACID

4,6-DICHLORONICOTINIC ACID

4,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID

2,4-Dichloro-5-carboxypyridine

2,4-Dichloro-5-pyridinecarboxylic acid

2,4-Dichloro-5-carboxylpyridine ,97%

4,6-Dichloronicotinic acid ,97%

4,6-Dichloropyridin-3-carboxylic acid

2,4-Dichloropyridine-5-carboxylic acid, 4,6-Dichloropyridine-3-carboxylic acid

4,6-Dichloro-3-pyridinecarboxylic acid

3-Pyridinecarboxylic acid, 4,6-dichloro-

4,6-Dichloronicotinic Acid(WX614282)

4,6-DichloronicotinicAci

4,6-Dichloronicotinic acid ISO 9001：2015 REACH

73027-79-9

C5H2Cl2NO2

Pyridine

Pyridines