ChemicalBook > CAS DataBase List > N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide

N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide

Product Name
N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide
CAS No.
171887-03-9
Chemical Name
N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide
Synonyms
N-(2-Amino-4,6-dichloropyrimidin-5-yl)formamide;2-Amino-4,6-dichloro-5-pyrimidinyl formamide;JACS-171887-03-9;2-Amino-4,6-dichloro-5-;N-(2-Amino-4,6-Dichloro-5-Pyri;2,5-Diamino-4,6-DichloroformamidoHcl;2-amino-4,6-dichloro-5-formamidopyrimidin;2-Amino-4,6-dichloro-5-formamidopyrimidine;2-Amino-4,6-dichloro-5-formanido pyrimidine;2-Amino-4,6-dichloro-5-formamidopyrimidine >
CBNumber
CB5547319
Molecular Formula
C5H4Cl2N4O
Formula Weight
207.02
MOL File
171887-03-9.mol
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N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide Property

Melting point:
>251°C (dec.)
Boiling point:
554.8±60.0 °C(Predicted)
Density 
1.742±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMSO, Methanol
form 
Solid
pka
10.90±0.70(Predicted)
color 
Off-White to Pale Beige
CAS DataBase Reference
171887-03-9(CAS DataBase Reference)
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Safety

HS Code 
2933.59.9500
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2146
Product name
2-Amino-4,6-dichloro-5-formamidopyrimidine
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$38
Updated
2024/03/01
TCI Chemical
Product number
A2146
Product name
2-Amino-4,6-dichloro-5-formamidopyrimidine
Purity
>98.0%(HPLC)(N)
Packaging
25g
Price
$124
Updated
2024/03/01
TRC
Product number
A604735
Product name
N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide
Packaging
25g
Price
$130
Updated
2021/12/16
AK Scientific
Product number
J55220
Product name
2-Amino-4,6-dichloro-5-formamidopyrimidine
Packaging
5g
Price
$10
Updated
2021/12/16
AK Scientific
Product number
Q340
Product name
2-Amino-4,6-dichloro-5-formamidopyrimidine
Packaging
5g
Price
$14
Updated
2021/12/16
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N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Uses

N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide (Abacavir - In House Impurity) is an intermediate of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

Uses

Prasugrel intermediate

Uses

Abacavir intermediate. A purine derivative

N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide Preparation Products And Raw materials

Raw materials

Barbituric acid Heptane Aluminium-nickel Ammonium hydroxide Ethanol Sodium sulfate Toluene Formic acid Phosphorus oxychloride Diethyl ether Nitric acid Sodium hydroxide N,N-Diethylaniline

Preparation Products

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N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide Suppliers

Americas 1 Canada 2 China 240 Europe 4 Germany 4 India 70 Japan 1 Russia 1 Slovakia 1 United Kingdom 8 United States 28 Global 360
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View Lastest Price from N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide 171887-03-9
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-11
Shaanxi Dideu Medichem Co. Ltd
Product
N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide 171887-03-9
Price
US $0.01-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50 tons
Release date
2020-05-19
Shaanxi Dideu Medichem Co. Ltd
Product
N-(2-AMINO-4,6-DICHLORO-5-PYRIMIDINYL)FORMAMIDE
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500 tons
Release date
2020-05-20

171887-03-9, N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamideRelated Search:

ALTRENOGEST 4,6-Dichloropyrimidine 2-Amino-4,6-dichloropyrimidine p-Aminobenzamide Tris(hydroxymethyl)aminomethane Benzamide Dichloroacetic acid 6-Aminocaproic acid Formamide Glycine Chlorantraniliprole 2-Aminopyrimidine N,N-Dimethylformamide 5-Cyanophthalide 2,5-Diamino-4,6-dihydroxypyrimidine hydrochloride 1,2,3-Triacetyl-5-deoxy-D-ribose 5-Amino-4,6-dichloropyrimidine 2,5-Diamino-4,6-dichloropyrimidine

  • N-(2-Amino-4.6-dichloro-5-pyrimdinyl) formamide
  • 2-Amino-4,6-dichloro-5-pyrimidinyl formamide
  • 2,5-Diamino-4,6-DichloroformamidoHcl
  • N-(2-Amino-4,6-Dichloro-5-Pyri
  • N-(2-AMINO-4,6-DICHLOROPYRIMIDIN-5-YL) FORMAMIDE[FOR ABACAVIR]
  • N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide
  • N-(2-Amino-4,6-dichloropyrimidin-5-yl)formamide
  • 2-Amino-4,6-dichloro-5-formamidopyrimidine
  • 2-Amino-4,6-dichloro-5-
  • N-(2-aMino-4,6-dichloro-1,2-dihydropyriMidin-5-yl) forMaMide
  • N-(2-aMino-4,6-dichloro-1,2-dihydropyriMidin-5-yl)
  • 2-Amino-4,6-dichloro-5-formanido pyrimidine
  • 2- aMino-4,6- twochloro -5-forMaMido pyriMidine
  • N-(2- aMino-4,6- twochloro -5-pyriMidinyl)forMaMide
  • ForMaMide,N-(2-aMino-4,6-dichloro-5-pyriMidinyl)-
  • JACS-171887-03-9
  • 2-Amino-4,6-dichloro-5-formamidopyrimidine (FADCP)
  • 2-Amino-4,6-dichloro-5-formamidopyrimidine &gt
  • N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide ISO 9001：2015 REACH
  • N-(2-Amino-4,6-Dicloro-5-Pyrimidinyl) Formamide
  • N-(2-Amino-4,6-Dichloro-5-pyrmidinyl)formamide
  • 2-amino-4,6-dichloro-5-formamidopyrimidin
  • N-(2-Amino-4,6-Dichloro- Pyrimidin-5-yl) Formamide(FADCP)
  • 171887-03-9
  • Heterocycle-Pyrimidine series
  • Bases & Related Reagents
  • Heterocycles
  • Nucleotides
  • Heterocyclic Compounds
  • Heterocycle
  • 3