ChemicalBook > CAS DataBase List > VU0238441
VU0238441
- Product Name
- VU0238441
- CAS No.
- 85511-68-8
- Chemical Name
- VU0238441
- Synonyms
- VU0238441;7-Chloro-1-(4-(trifluoromethyl)benzyl)indoline-2,3-dione;7-chloro-1-[[4-(trifluoromethyl)phenyl]methyl]indole-2,3-dione;7-Chloro-1-[[4-(trifluoromethyl)phenyl]methyl]-1H-indole-2,3-dione;1H-Indole-2,3-dione, 7-chloro-1-[[4-(trifluoroMethyl)phenyl]Methyl]-;mAChR,Inhibitor,VU-0238441,VU0238441,Muscarinic acetylcholine receptor,VU 0238441,inhibit
- CBNumber
- CB62628523
- Molecular Formula
- C16H9ClF3NO2
- Formula Weight
- 339.7
- MOL File
- 85511-68-8.mol
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VU0238441 Property
- Boiling point:
- 441.7±55.0 °C(Predicted)
- Density
- 1.500±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO: 125 mg/mL (367.97 mM)
- pka
- -3?+-.0.20(Predicted)
- form
- Solid
- color
- Brown to red
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0003123
- Product name
- VU0238441
- Purity
- ≥97.0%
- Packaging
- 5mg
- Price
- $50
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0003123
- Product name
- VU0238441
- Purity
- ≥97.0%
- Packaging
- 10mg
- Price
- $70
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0003123
- Product name
- VU0238441
- Purity
- ≥97.0%
- Packaging
- 25mg
- Price
- $130
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0003123
- Product name
- VU0238441
- Purity
- ≥97.0%
- Packaging
- 50mg
- Price
- $180
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0003123
- Product name
- VU0238441
- Purity
- ≥97.0%
- Packaging
- 100mg
- Price
- $250
- Updated
- 2021/12/16
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VU0238441 Chemical Properties,Usage,Production
Biological Activity
VU0238441 is a positive allosteric modulator (PAM) of pan-muscarinic acetylcholine receptor (mAChR) with EC50 values of 2.1 μM, 2.2 μM, 2.8 μM, 3.2 μM and > 2.1 μM, 2.2 μM, 2.8 μM, 3.2 μM and > for M5, M3, M2, M1 and M4, respectively 10 μM.
in vitro
VU0238441 is an analogue of VU0119498.
target
Target | Value |
mAChR M5 (Cell-free assay) | < td style="border-bottom: 1px dotted #ccc;padding: 5px;"> 2.1 μM|
mAChR M3 (Cell-free assay) | 2.2 μM |
mAChR M2 (Cell-free assay) | 2.8 μM |
mAChR M1 (Cell-free assay) | 3.2 μM |
mAChR M4 (Cell-free assay) | >10 μM |
VU0238441 Preparation Products And Raw materials
Raw materials
Preparation Products
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VU0238441 Suppliers
- Tel
- 021-52996696,15000506266 15000506266
- Fax
- +86-21-52996696
- Country
- China
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- sales@chemrenpharm.com
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- China
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