VU0238441

Product Name: VU0238441
CAS No.: 85511-68-8
Chemical Name: VU0238441
Synonyms: VU0238441;7-Chloro-1-(4-(trifluoromethyl)benzyl)indoline-2,3-dione;7-chloro-1-[[4-(trifluoromethyl)phenyl]methyl]indole-2,3-dione;7-Chloro-1-[[4-(trifluoromethyl)phenyl]methyl]-1H-indole-2,3-dione;1H-Indole-2,3-dione, 7-chloro-1-[[4-(trifluoroMethyl)phenyl]Methyl]-;mAChR,Inhibitor,VU-0238441,VU0238441,Muscarinic acetylcholine receptor,VU 0238441,inhibit
CBNumber: CB62628523
Molecular Formula: C16H9ClF3NO2
Formula Weight: 339.7
MOL File: 85511-68-8.mol

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VU0238441 Property

Boiling point:: 441.7±55.0 °C(Predicted)
Density: 1.500±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO: 125 mg/mL (367.97 mM)
pka: -3?+-.0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0003123
Product name: VU0238441
Purity: ≥97.0%
Packaging: 5mg
Price: $50
Updated: 2021/12/16

ChemScene

Product number: CS-0003123
Product name: VU0238441
Purity: ≥97.0%
Packaging: 10mg
Price: $70
Updated: 2021/12/16

ChemScene

Product number: CS-0003123
Product name: VU0238441
Purity: ≥97.0%
Packaging: 25mg
Price: $130
Updated: 2021/12/16

ChemScene

Product number: CS-0003123
Product name: VU0238441
Purity: ≥97.0%
Packaging: 50mg
Price: $180
Updated: 2021/12/16

ChemScene

Product number: CS-0003123
Product name: VU0238441
Purity: ≥97.0%
Packaging: 100mg
Price: $250
Updated: 2021/12/16

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VU0238441 Chemical Properties,Usage,Production

Biological Activity

VU0238441 is a positive allosteric modulator (PAM) of pan-muscarinic acetylcholine receptor (mAChR) with EC50 values of 2.1 μM, 2.2 μM, 2.8 μM, 3.2 μM and > 2.1 μM, 2.2 μM, 2.8 μM, 3.2 μM and > for M5, M3, M2, M1 and M4, respectively 10 μM.

in vitro

VU0238441 is an analogue of VU0119498.

target

< td style="border-bottom: 1px dotted #ccc;padding: 5px;"> 2.1 μM

Target	Value
mAChR M5 (Cell-free assay)
mAChR M3 (Cell-free assay)	2.2 μM
mAChR M2 (Cell-free assay)	2.8 μM
mAChR M1 (Cell-free assay)	3.2 μM
mAChR M4 (Cell-free assay)	>10 μM

VU0238441 Preparation Products And Raw materials

Raw materials

Preparation Products

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VU0238441 Suppliers

China 25 United States 4 Global 29

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
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Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
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Email: klq@cw-bio.com
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ShangHai Biochempartner Co.,Ltd

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Shanghai Chaolan Chemical Technology Center

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Twochem Co.Ltd.

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Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471 +1-2135480471
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InvivoChem

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DC Chemicals

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Changzhou Chenhong Biotechnology Co., Ltd.

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Email: sales@chemrenpharm.com
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ShangHai ChuanQian Chemcial Technique Centre

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Email: 3525679403@qq.com
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85511-68-8, VU0238441Related Search:

VU0134992(hydrochloride) VU6012962 VU0810464 VU6015929 N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide 1-(4-Methoxybenzyl)-5-trifluoromethoxyisatin VUN65671 VU 0357121 VU6010608 VU 0364439 VU-29 2-[2-bromo-4-(propan-2-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)acetamide VUF 10460 VUF 10166 N6022 VU 0357017 hydrochloride VU 0364770 1-(4-BROMOBENZYL)INDOLE-2,3-DIONE

VU0238441

1H-Indole-2,3-dione, 7-chloro-1-[[4-(trifluoroMethyl)phenyl]Methyl]-

7-chloro-1-[[4-(trifluoromethyl)phenyl]methyl]indole-2,3-dione

7-Chloro-1-[[4-(trifluoromethyl)phenyl]methyl]-1H-indole-2,3-dione

7-Chloro-1-(4-(trifluoromethyl)benzyl)indoline-2,3-dione

mAChR,Inhibitor,VU-0238441,VU0238441,Muscarinic acetylcholine receptor,VU 0238441,inhibit

85511-68-8