ChemicalBook > CAS DataBase List > VU0238441

VU0238441

Product Name
VU0238441
CAS No.
85511-68-8
Chemical Name
VU0238441
Synonyms
VU0238441;7-Chloro-1-(4-(trifluoromethyl)benzyl)indoline-2,3-dione;7-chloro-1-[[4-(trifluoromethyl)phenyl]methyl]indole-2,3-dione;7-Chloro-1-[[4-(trifluoromethyl)phenyl]methyl]-1H-indole-2,3-dione;1H-Indole-2,3-dione, 7-chloro-1-[[4-(trifluoroMethyl)phenyl]Methyl]-;mAChR,Inhibitor,VU-0238441,VU0238441,Muscarinic acetylcholine receptor,VU 0238441,inhibit
CBNumber
CB62628523
Molecular Formula
C16H9ClF3NO2
Formula Weight
339.7
MOL File
85511-68-8.mol
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VU0238441 Property

Boiling point:
441.7±55.0 °C(Predicted)
Density 
1.500±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO: 125 mg/mL (367.97 mM)
pka
-3?+-.0.20(Predicted)
form 
Solid
color 
Brown to red
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0003123
Product name
VU0238441
Purity
≥97.0%
Packaging
5mg
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-0003123
Product name
VU0238441
Purity
≥97.0%
Packaging
10mg
Price
$70
Updated
2021/12/16
ChemScene
Product number
CS-0003123
Product name
VU0238441
Purity
≥97.0%
Packaging
25mg
Price
$130
Updated
2021/12/16
ChemScene
Product number
CS-0003123
Product name
VU0238441
Purity
≥97.0%
Packaging
50mg
Price
$180
Updated
2021/12/16
ChemScene
Product number
CS-0003123
Product name
VU0238441
Purity
≥97.0%
Packaging
100mg
Price
$250
Updated
2021/12/16
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VU0238441 Chemical Properties,Usage,Production

Biological Activity

VU0238441 is a positive allosteric modulator (PAM) of pan-muscarinic acetylcholine receptor (mAChR) with EC50 values of 2.1 μM, 2.2 μM, 2.8 μM, 3.2 μM and > 2.1 μM, 2.2 μM, 2.8 μM, 3.2 μM and > for M5, M3, M2, M1 and M4, respectively 10 μM.

in vitro

VU0238441 is an analogue of VU0119498.

target

< td style="border-bottom: 1px dotted #ccc;padding: 5px;"> 2.1 μM
TargetValue
mAChR M5
(Cell-free assay)
mAChR M3
(Cell-free assay)		 2.2 μM
mAChR M2
(Cell-free assay)		 2.8 μM
mAChR M1
(Cell-free assay)		 3.2 μM
mAChR M4
(Cell-free assay)		 >10 μM

VU0238441 Preparation Products And Raw materials

Raw materials

Preparation Products

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VU0238441 Suppliers

China 27 United States 5 Global 32
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32080
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38470
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58

85511-68-8, VU0238441Related Search:

VU0134992(hydrochloride) VU6012962 VU0810464 VU6015929 N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide 1-(4-Methoxybenzyl)-5-trifluoromethoxyisatin VUN65671 VU 0357121 VU6010608 VU 0364439 VU-29 2-[2-bromo-4-(propan-2-yl)phenoxy]-N-(2,2,6,6-tetramethylpiperidin-4-yl)acetamide VUF 10460 VUF 10166 N6022 VU 0357017 hydrochloride VU 0364770 1-(4-BROMOBENZYL)INDOLE-2,3-DIONE

  • VU0238441
  • 1H-Indole-2,3-dione, 7-chloro-1-[[4-(trifluoroMethyl)phenyl]Methyl]-
  • 7-chloro-1-[[4-(trifluoromethyl)phenyl]methyl]indole-2,3-dione
  • 7-Chloro-1-[[4-(trifluoromethyl)phenyl]methyl]-1H-indole-2,3-dione
  • 7-Chloro-1-(4-(trifluoromethyl)benzyl)indoline-2,3-dione
  • mAChR,Inhibitor,VU-0238441,VU0238441,Muscarinic acetylcholine receptor,VU 0238441,inhibit
  • 85511-68-8