4-(Trifluoromethoxy)benzoic acid Property

Melting point:

150-154 °C(lit.)

Boiling point:

203°C (rough estimate)

Density 

1.4251 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform, Methanol

form 

Powder

pka

3.85±0.10(Predicted)

color 

White to cream

BRN 

977356

InChIKey

RATSANVPHHXDCT-UHFFFAOYSA-N

CAS DataBase Reference

330-12-1(CAS DataBase Reference)

NIST Chemistry Reference

4-(Trifluoromethoxy)benzoic acid(330-12-1)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29189900

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

4-(Trifluoromethoxy)benzoic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

4-(Trifluoromethoxy)benzoic Acid is a substituted benzoic acid used in the preparation of a various biologically active compounds such as antifungal and antimalarial agents.

General Description

Kinetics of internal acyl migration and hydrolysis of the synthetic β-1-O-acyl-D-glucopyranuronates of 2-, 3-, and 4-(trifluoromethyl)benzoic acids in phosphate buffer was studied.