ChemicalBook > CAS DataBase List > N-Chlorosuccinimide

N-Chlorosuccinimide

Product Name
N-Chlorosuccinimide
CAS No.
128-09-6
Chemical Name
N-Chlorosuccinimide
Synonyms
NCS;Chlorosuccinimide;N-CHLOROSUCCINAMIDE;N-Chlorosuccinimide (NCS);1-Chloro-2,5-piperidinedione;N-Chlorosuccinimide≥ 99% (Iodometric Titration);NSC 8748;orosuccinimide;APM (Aspartame);SUCCINCHLORIMIDE
CBNumber
CB7141683
Molecular Formula
C4H4ClNO2
Formula Weight
133.53
MOL File
128-09-6.mol
More
Less

N-Chlorosuccinimide Property

Melting point:
148-150 °C (lit.)
Density 
1,65 g/cm3
bulk density
600kg/m3
vapor pressure 
1.04Pa at 25℃
refractive index 
1.4378 (estimate)
Flash point:
>110°C
storage temp. 
Store at +2°C to +8°C.
solubility 
14g/l
pka
-2.78±0.20(Predicted)
form 
Crystalline Powder
color 
White
Odor
chlorine odor
Water Solubility 
Soluble in water, alcohol, benzene, acetone and acetic acid. Slightly soluble in ether, chloroform, carbon tetrachloride and petroleum ether.
Sensitive 
Moisture Sensitive
Merck 
14,2164
Boiling point:
216.5°C
BRN 
113915
InChIKey
JRNVZBWKYDBUCA-UHFFFAOYSA-N
LogP
-1.19
CAS DataBase Reference
128-09-6(CAS DataBase Reference)
NIST Chemistry Reference
N-Chlorosuccinimide(128-09-6)
EPA Substance Registry System
N-Chlorosuccinimide (128-09-6)
More
Less

Safety

Hazard Codes 
C,Xi
Risk Statements 
22-34
Safety Statements 
26-36/37/39-45-37/39
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
RTECS 
UY1013500
F 
21
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29251995
Hazardous Substances Data
128-09-6(Hazardous Substances Data)
Toxicity
MLD orally in rats: 2.7 g/kg (Stohlman, Smith)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H290May be corrosive to metals

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.02811
Product name
N-Chlorosuccinimide
Purity
for synthesis
Packaging
5G
Price
$38.2
Updated
2024/03/01
Sigma-Aldrich
Product number
8.02811
Product name
N-Chlorosuccinimide
Purity
for synthesis
Packaging
250g
Price
$88.6
Updated
2024/03/01
Sigma-Aldrich
Product number
109681
Product name
N-Chlorosuccinimide
Purity
98%
Packaging
100g
Price
$33.1
Updated
2024/03/01
Sigma-Aldrich
Product number
109681
Product name
N-Chlorosuccinimide
Purity
98%
Packaging
500g
Price
$104
Updated
2024/03/01
TCI Chemical
Product number
C0291
Product name
N-Chlorosuccinimide
Purity
>98.0%(T)
Packaging
25g
Price
$16
Updated
2024/03/01
More
Less

N-Chlorosuccinimide Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

N-Chlorosuccinimide is a chlorinating agent for the side-chain halogenation of alkylarenes. It is used frequently for the side-chain chlorination of sensitive hetarenes.

Uses

N-Chlorosuccinimide (NCS) is a chlorinating and oxidizing reagent. It is more efficient when compared to other chlorinating agents, such as 1,3-dichloro-5,5-dimethylhydantoin (NDDH) and trichloroisocyanuric acid (TCCA) due to its high regioselectivity.
N-Chlorosuccinimide is used as a chlorinating agent, mild oxidant and swimming pool disinfectant. It is used in the microdetermination of hydrazine salts by titrimetry as well as in the detection of arsenic in the +3 oxidative state. It is also employed in the production of rubber additives. Further, it is used as pharmaceutical intermediate and antibiotic drugs intermediate.

Definition

ChEBI: N-chlorosuccinimide is a five-membered cyclic dicarboximide compound having a chloro substituent on the nitrogen atom. It is a pyrrolidinone and a dicarboximide. It derives from a succinimide.

Flammability and Explosibility

Non flammable

reaction suitability

reagent type: oxidant

N-Chlorosuccinimide Preparation Products And Raw materials

Raw materials

Sodium hypochlorite Chlorine Succinimide Sodium chlorate hypochlorous acid Succinic acid Ammonia

Preparation Products

5-Amino-2,3-dichloropyridine 5-CHLORO-2'-DEOXYURIDINE 5-Methyl-3-phenylisoxazole-4-carboxylic acid Tau-fluvalinate 2-CHLORO-4-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE 3-Chloro-2-hydroxy-5-nitropyridine (2-BUTYL-5-CHLORO-1H-IMIDAZOL-4-YL)METHANOL Cefaclor monohydrate 3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOLE-4-CARBALDEHYDE 2-Amino-5-chlorobenzonitrile 2-ETHYLCYCLOHEXANONE Ethyl 2-amino-4-phenyl-5-thiazolecarboxylate 2-Chloro-1,4-diaminobenzene 2,3-DICHLORO-5-NITROPYRIDINE 5,6-DICHLORONICOTINIC ACID ETHYL ESTER 3-(CHLOROMETHYL)-N,N-DIMETHYLBENZENESULFONAMIDE 2-Chloroquinoline Ketorolac 6-CHLOROQUINAZOLIN-4-AMINE 5-METHYLFURAN-2-BORONIC ACID 4'-Bromo-3'-fluoroacetanilide
More
Less

N-Chlorosuccinimide Suppliers

Americas 1 Belgium 1 Canada 1 China 543 Europe 3 Germany 4 India 40 Japan 6 Slovakia 1 South Korea 2 Switzerland 3 Ukraine 1 United Kingdom 11 United States 46 Global 663
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Accela ChemBio Inc.
Tel
--
Fax
--
Email
info@accelachem.com
Country
United States
ProdList
1054
Advantage
50
Richman Chemical Inc
Tel
--
Fax
--
Email
clk@RichmanChemical.com
Country
United States
ProdList
238
Advantage
58
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Sisco Research Laboratories Pvt. Ltd.
Tel
--
Fax
--
Email
srlmarketing@dishnetdsl.net
Country
United States
ProdList
1905
Advantage
64
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
ChemService Inc.
Tel
--
Fax
--
Country
United States
ProdList
6379
Advantage
68
Global ChemSources, Inc.
Tel
--
Fax
--
Email
sales@globalchemsources.com
Country
United States
ProdList
132
Advantage
30
Ryan Scientific, Inc.
Tel
--
Fax
--
Email
ryan.reichlyn@ryansci.com
Country
United States
ProdList
6439
Advantage
60
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
Advanced Synthesis Technologies
Tel
--
Fax
--
Email
sales@advancedsynthesis.com
Country
United States
ProdList
4775
Advantage
61
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Naugra Export
Tel
--
Fax
--
Country
United States
ProdList
1332
Advantage
47
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
AJ Organica Pvt. Ltd.
Tel
--
Fax
--
Email
info@ajorganica.com
Country
United States
ProdList
13
Advantage
34
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
Leonid Chemicals Private Limited
Tel
--
Fax
--
Email
careers@leonidchemicals.com
Country
United States
ProdList
1700
Advantage
43
PHT International Inc.
Tel
--
Fax
--
Email
pht@phtchemical.com
Country
United States
ProdList
97
Advantage
65
Sciencelab.com, Inc.
Tel
--
Fax
--
Email
accounting@sciencelab.com
Country
United States
ProdList
4159
Advantage
82
Loba Chemie Pvt. Ltd.
Tel
--
Fax
--
Country
United States
ProdList
1945
Advantage
71
City Chemical LLC
Tel
--
Fax
--
Email
sales@citychemical.com
Country
United States
ProdList
6708
Advantage
72
Acros Organics USA
Tel
--
Fax
--
Email
eveleth@fisherchem.com
Country
United States
ProdList
3846
Advantage
81
AB Chem Technologies, LLC
Tel
--
Fax
--
Email
sales@abchemtech.com
Country
United States
ProdList
1101
Advantage
46
GFS Chemicals
Tel
--
Fax
--
Email
gfschem@gfschemicals.com
Country
United States
ProdList
3403
Advantage
75
Pfaltz & Bauer, Inc.
Tel
--
Fax
--
Email
sales@pfaltzandbauer.com
Country
United States
ProdList
6828
Advantage
72
Aceto Corporation
Tel
--
Fax
--
Email
contact@aceto.com
Country
United States
ProdList
2619
Advantage
75
DSM Fine Chemicals Inc.
Tel
--
Fax
--
Country
United States
ProdList
151
Advantage
46
City Chemicals Corporation
Tel
--
Fax
--
Country
United States
ProdList
6460
Advantage
72
Eastern Chemical Corp.
Tel
--
Fax
--
Email
eastern@u-g.com
Country
United States
ProdList
2786
Advantage
34
ChemPacific Corporation
Tel
--
Fax
--
Email
sales@chempacific.com
Country
United States
ProdList
6891
Advantage
51
Richman Chemical Inc.
Tel
--
Fax
--
Email
kac@richmanchemical.com
Country
United States
ProdList
692
Advantage
67
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
MP Biomedicals, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6561
Advantage
81
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
More
Less

View Lastest Price from N-Chlorosuccinimide manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
N-Chlorosuccinimide 128-09-6
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-16
Hebei Mujin Biotechnology Co.,Ltd
Product
N-chlorosuccinimide 128-09-6
Price
US $9450.00/T
Min. Order
1KG
Purity
99%
Supply Ability
20tons
Release date
2020-06-29
Hubei Yiling biotechnology Co Ltd
Product
N-Chlorosuccinimide 128-09-6
Price
US $0.00/G/KG
Min. Order
1G/KG
Purity
99%
Supply Ability
100MT
Release date
2025-02-13

128-09-6, N-ChlorosuccinimideRelated Search:

Maleimide N-Iodosuccinimide N-Bromosuccinimide Succinimide O-Phthalimide N-Hydroxysuccinimide Bismaleimide N-Methoxy-N-methylacetamide DIALIFOS Difluorochloromethane N-CHLOROSUCCINIMIDE, 98+% N-PROPYLAMINE HYDROCHLORIDE BUTYLAMINE HYDROCHLORIDE Diethylamine hydrochloride DIACETAMIDE chloramide PYRROLIDINEHYDROCHLORIDE N-CHLOROSUCCINIMIDE (67.2.6)

  • 1-Chloro-2,5-piperidinedione
  • Pyrrolidinedione, 1-chloro-
  • Succinic N-chloroimide
  • succinicn-chloroimide
  • Succinimide, N-chloro-
  • Succinochlorimide
  • N-Chlorosuccini1mide
  • N-ChlorosucciniMide, 98.5%
  • N-Chlorosuccinimide≥ 99% (Iodometric Titration)
  • NCS
  • APM (Aspartame)
  • N-Succinchlorimide
  • Succinochloroimide
  • N-Chlorosuccinimide,97%
  • N-Chlorosuccinamide (NCS)
  • N-Chlorosuccinimide ,97.5%
  • N-ChlorosuccinimideDISC 18.03.04
  • N-ChlorosucciniMide, 97% 100GR
  • N-ChlorosucciniMide, 97% 500GR
  • N-ChlorobutaniMide / N-ChlorosucciniMide
  • 1-Chloropyrrolidine-2,5-dione, 1-Chloro-2,5-dioxopyrrolidine
  • <i>N</i>-Chlorosuccinimide
  • orosuccinimide
  • 1-chloro-5-pyrrolidinedione
  • 5-Pyrrolidinedione,1-chloro-2
  • imide,n-chloro-succinicaci
  • n-chloro-succinimid
  • SUCCINCHLORIMIDE
  • N-CHLOROSUCCINAMIDE
  • N-CHLOROSUCCINIMIDE
  • N-CHLOROBUTANIMIDE
  • Chlorosuccinimide
  • CHLOROSUCCINIMIDE(N-)
  • 2,5-PYRROLIDINEDIONE, 1-CHLORO-
  • 1-CHLORO-2,5-PYRROLIDINEDIONE
  • N-Chlorosuccinnimide
  • N-ChlorosuccinimideForSynthesis
  • N-Chlorosuccinimide, 99+%
  • N-CHLOROSUCCINIMIDE (1-CHLORO-2,5-PYRROLIDINEDIONE)
  • N-Chlor-succinimid
  • N-BROMO SUCCINIMIDE, N-CHLORO SUCCINIMIDE
  • N-Chlorosuccinimide (NCS)
  • CHLOROSUCCINAMIDE
  • N-CHLOROSUCCINIMIDE extrapure
  • 1-Chloro-pyrrolidine-2,5-dione
  • N-chlorosuccinimide(N-chlorobutanimide)
  • N-Chlorosuccinimie
  • N-Chlorosuccinimide &gt
  • N-Chlorosuccinimide, 97.5%, for synthesis
  • N-Chlorosuccinnimide/NCS
  • N-chlorobutylene imide
  • n-Chlorosuccinimide for synthesis 100GM
  • N-Chlorosuccinimide?New
  • N-CHOLROSUCCINIMIDE
  • 1-Chloro-Pyrrolidinedione
  • NSC 8748
  • n-Chlorosuccinimide 98% For Synthesis
  • 128-09-6