4-Bromophenol
- Product Name
- 4-Bromophenol
- CAS No.
- 106-41-2
- Chemical Name
- 4-Bromophenol
- Synonyms
- P-BROMOPHENOL;Para Bromo Phenol;4-Bromphenol;Phenol, 4-bromo-;NSC 4970;p-Bromphenol;4-BROMOPHENOL;BROMOPHENOL-4;P-Bromophenlo;4-bromo-pheno
- CBNumber
- CB7181317
- Molecular Formula
- C6H5BrO
- Formula Weight
- 173.01
- MOL File
- 106-41-2.mol
4-Bromophenol Property
- Melting point:
- 61-64 °C (lit.)
- Boiling point:
- 235-236 °C (lit.)
- Density
- 1.84
- refractive index
- 1.5085 (estimate)
- Flash point:
- 235-238°C
- storage temp.
- room temp
- solubility
- 14g/l
- form
- Crystalline Solid
- pka
- 9.37(at 25℃)
- color
- Pinkish-brown
- Water Solubility
- It is insoluble in water. It is soluble in 5%ethanol.
- λmax
- 282nm(EtOH)(lit.)
- Merck
- 14,1428
- BRN
- 1680024
- CAS DataBase Reference
- 106-41-2(CAS DataBase Reference)
- NIST Chemistry Reference
- 4-Bromophenol(106-41-2)
- EPA Substance Registry System
- Phenol, 4-bromo- (106-41-2)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38-20/21/22
- Safety Statements
- 26-37/39-36
- RIDADR
- 2811
- WGK Germany
- 2
- RTECS
- SJ7960000
- F
- 8-10-23
- Hazard Note
- Irritant
- TSCA
- Yes
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29081000
- Hazardous Substances Data
- 106-41-2(Hazardous Substances Data)
- Toxicity
- mouse,LD50,intraperitoneal,411mg/kg (411mg/kg),Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 44(12), Pg. 19, 1979.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B75808
- Product name
- 4-Bromophenol
- Purity
- 99%
- Packaging
- 5g
- Price
- $37.5
- Updated
- 2024/03/01
- Product number
- B75808
- Product name
- 4-Bromophenol
- Purity
- 99%
- Packaging
- 100g
- Price
- $76.3
- Updated
- 2024/03/01
- Product number
- B0787
- Product name
- 4-Bromophenol
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $19
- Updated
- 2024/03/01
- Product number
- B0787
- Product name
- 4-Bromophenol
- Purity
- >98.0%(GC)(T)
- Packaging
- 100g
- Price
- $33
- Updated
- 2024/03/01
- Product number
- A14873
- Product name
- 4-Bromophenol, 99%
- Packaging
- 100g
- Price
- $61.8
- Updated
- 2024/03/01
4-Bromophenol Chemical Properties,Usage,Production
Chemical Properties
4-Bromophenol is a pinkish-brown crystalline solid. four-sided biconical crystal precipitated from ether or chloroform. The melting point is 66.4 ℃, and a small amount of water can reduce the melting point a lot. Soluble in water, chloroform, easily soluble in ethanol, ether and glacial acetic acid, soluble in 7 parts of water.
Uses
4-Bromophenol is used as an intermediate in medicine grade. It is also used as a phenol that is used in Stille reactions. It is used in the intermediate of organic synthesis, flame retardant and pharmaceutical industry.
Application
4-Bromophenol is a phenolic derivative that It can used as a reagent in Stille reactions or Intermediates of Liquid Crystals.
Preparation
4-Bromophenol is synthesized by bromination of phenol. The bromine and carbon disulfide solution was added to the phenolic carbon disulfide solution, and the addition was started below 5°C, and the addition was completed under stirring for 2 hours. Phenol and bromine are approximately equimolar ingredients. Distill the reactant to remove carbon disulfide, and then conduct fractional distillation under reduced pressure to collect fractions at 145-150°C (3.32-3.99kPa) to obtain the product. Yield 80-84%.
Definition
ChEBI: 4-bromophenol is a bromophenol containing only hydroxy and bromo substituents that are para to one another. It has a role as a mouse metabolite, a persistent organic pollutant, a human xenobiotic metabolite, a rat metabolite, a human urinary metabolite and a marine metabolite.
Synthesis Reference(s)
Tetrahedron, 45, p. 7869, 1989 DOI: 10.1016/S0040-4020(01)85800-2
The Journal of Organic Chemistry, 23, p. 280, 1958 DOI: 10.1021/jo01096a033
Purification Methods
Crystallise the phenol from CHCl3, CCl4, pet ether (b 40-60o), or water and dry it at 70o under vacuum for 2hours. [Beilstein 6 IV 1043.]
4-Bromophenol Preparation Products And Raw materials
Raw materials
Preparation Products
4-Bromophenol Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
- Tel
- --
- Fax
- --
- export@ecochem.dk
- Country
- Europe
- ProdList
- 6371
- Advantage
- 66
- Tel
- --
- Fax
- --
- Sales@kemikalieimport.dk
- Country
- Europe
- ProdList
- 6685
- Advantage
- 47
View Lastest Price from 4-Bromophenol manufacturers
- Product
- P-Bromophenol 106-41-2
- Price
- US $0.00/kg
- Min. Order
- 20kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2024-09-29
- Product
- 4-Bromophenol 106-41-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-10-24
- Product
- 4-Bromophenol 106-41-2
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-09-20