ChemicalBook > CAS DataBase List > DBCO-PEG4-biotin

DBCO-PEG4-biotin

Product Name
DBCO-PEG4-biotin
CAS No.
1255942-07-4
Chemical Name
DBCO-PEG4-biotin
Synonyms
Biotin-PEG4-DBCO;DBCO-PEG4-biotin;DBCO-NH-PEG4-Biotin;ADIBO-NH-PEG2-Biotin;Dibenzocyclooctyne-PEG4-biotin conjugate;Azadibenzocyclooctyne-PEG4-Biotin conjugate;Dibenzocyclooctyne-PEG4-biotin conjugate for Copper-free Click Chemistry;1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[19-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-15,19-dioxo-3,6,9,12-tetraoxa-16-azanonadec-1-yl]hexahydro-2-oxo-, (3aS,4S,6aR)-;1-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}-N-(3-{2-azatricyclo[10.4.0.0\\u2074,\\u2079]hexadeca-1(12),4(9),5,7,13,15-hexaen-10-yn-2-yl}-3-oxopropyl)-3,6,9,12-tetraoxapentadecan-15-amide
CBNumber
CB72750885
Molecular Formula
C39H51N5O8S
Formula Weight
749.92
MOL File
1255942-07-4.mol
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DBCO-PEG4-biotin Property

Boiling point:
1062.4±65.0 °C(Predicted)
Density 
1.30±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in Water, DMSO, DMF, DCM
pka
13.90±0.40(Predicted)
form 
Solid
color 
Off-white to yellow
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
760749
Product name
Dibenzocyclooctyne-PEG4-biotin conjugate
Purity
for Copper-free Click Chemistry
Packaging
5mg
Price
$108
Updated
2024/03/01
TRC
Product number
D194993
Product name
DBCO-PEG4-Biotin
Packaging
1mg
Price
$65
Updated
2021/12/16
Chem-Impex
Product number
35067
Product name
Biotin-PEG4-DBCO,95%(HPLC)
Purity
95%(HPLC)
Packaging
5MG
Price
$151.2
Updated
2021/12/16
Chem-Impex
Product number
35067
Product name
Biotin-PEG4-DBCO,95%(HPLC)
Purity
95%(HPLC)
Packaging
25MG
Price
$302.4
Updated
2021/12/16
Iris Biotech GmbH
Product number
RL-2520
Product name
Biotin-PEG(4)-DBCO
Packaging
100mg
Price
$1080
Updated
2021/12/16
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DBCO-PEG4-biotin Chemical Properties,Usage,Production

Description

DBCO-PEG4-biotin is a click chemistry biotinylation that can enable copper-free click chemistry with azide molecules to form a stable triazole linkage. PEG4 spacer increases aqueou solubility of the molecules conjugated to the biotin compound.

Uses

activity-based protein profiling detection of newly synthesized proteins immobilization of azide-labeled biomolecules.

Uses

DBCO-PEG4-Biotin is used in preparation of array-based cyclic peptide libraries.

General Description

This azadibenzocyclooctyne-biotin derivative is a versatile biotinylation reagent for labeling azide containing molecules or compounds. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions.This dibenzocyclooctyne will react with azide-functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. Subsequent labeled molecules can be purified using streptavidin or avidin affinity reagents. The PEG spacer makes the overall compound more hydrophilic and allows for greater distance between the reaction site with the azide and the biotin detecting group.

reaction suitability

reaction type: click chemistry

storage

Store at -20°C

DBCO-PEG4-biotin Preparation Products And Raw materials

Raw materials

Preparation Products

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DBCO-PEG4-biotin Suppliers

China 51 India 1 United States 7 Global 59
Xi'an Confluore Biological Technology Co., Ltd.
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View Lastest Price from DBCO-PEG4-biotin manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Biotin-PEG4-DBCO 1255942-07-4
Price
US $0.00/mg
Min. Order
5mg
Purity
>98.00%
Supply Ability
25mg
Release date
2024-03-20

1255942-07-4, DBCO-PEG4-biotinRelated Search:

Polyethylene Glycol D-Biotin DBCO-PEG4-amine DBCO-amine DBCO-PEG4-SE DBCO-PEG4-amine UV Cleavable Biotin-PEG2-Azide Biotin-PEG4-Methyltetrazine Acetylene-PEG4-biotin conjugate Biotin-PEG2-azide Biotin-PEG4-N3 Biotin-PEG<sub>4</sub>-Azide Biotin-PEG2-C4-Alkyne 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-2-oxo-N-2-propynyl-, (3aS,4S,6aR)- (3aS,4S,6aR)-Hexahydro-2-oxo-N-(15-oxo-3,6,9,12-tetraoxa-16-azanonadec-18-yn-1-yl)-1H-thieno[3,4-d]imidazole-4-pentanamide Azide-SS-biotin (4E)-TCO-PEG4-biotin Biotin-PEG4- Picolyl Azide

  • Dibenzocyclooctyne-PEG4-biotin conjugate for Copper-free Click Chemistry
  • Azadibenzocyclooctyne-PEG4-Biotin conjugate
  • DBCO-NH-PEG4-Biotin
  • DBCO-PEG4-biotin
  • Dibenzocyclooctyne-PEG4-biotin conjugate
  • Biotin-PEG4-DBCO
  • ADIBO-NH-PEG2-Biotin
  • 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[19-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-15,19-dioxo-3,6,9,12-tetraoxa-16-azanonadec-1-yl]hexahydro-2-oxo-, (3aS,4S,6aR)-
  • 1-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}-N-(3-{2-azatricyclo[10.4.0.0\\u2074,\\u2079]hexadeca-1(12),4(9),5,7,13,15-hexaen-10-yn-2-yl}-3-oxopropyl)-3,6,9,12-tetraoxapentadecan-15-amide
  • 1255942-07-4
  • C39H51N5O8S