Pomalidomide-PEG4-azide

Product Name: Pomalidomide-PEG4-azide
CAS No.: 2271036-47-4
Chemical Name: Pomalidomide-PEG4-azide
Synonyms: Pomalidomide-PEG?-Azide;Pomalidomide-PEG4-azide;Pomalidomide-NH-?PEG4-?azide;4-((14-azido-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;14-Azido-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-3,6,9,12-tetraoxatetradecanamide, Crosslinker-E3 ligase ligand conjugate, Pomalidomide conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
CBNumber: CB78054794
Molecular Formula: C23H30N6O8
Formula Weight: 518.53
MOL File: 2271036-47-4.mol

More

Less

Pomalidomide-PEG4-azide Property

storage temp.: 2-8°C

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

Pomalidomide-PEG4-azide Chemical Properties,Usage,Production

Uses

Protein degrader builiding block Pomalidomide-PEG₄-Azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant azide for click chemistry with a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant azide, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

storage

Store at -20°C

Pomalidomide-PEG4-azide Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Pomalidomide-PEG4-azide Suppliers

China 25 United States 2 Global 27

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57511
Advantage: 58

More

Less

View Lastest Price from Pomalidomide-PEG4-azide manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Pomalidomide-NH-PEG4-azide 2271036-47-4
Price: US $0.00/mg
Min. Order: 100mg
Purity: >95.00%
Supply Ability: 100mg
Release date: 2024-04-01

2271036-47-4, Pomalidomide-PEG4-azideRelated Search:

Pomalidomide-PEG2-N3 Pomalidomide-PEG2-butyl iodide E3 Ligase Ligand-Linker Conjugates 22 4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Pomalidomide-PEG4-CO2H E3 Ligase Ligand-Linker Conjugates 1 POMALIDOMIDE-PEG2-CO2H Pomalidomide-PEG1-azide Pomalidomide-PEG5-CO2H POMALIDOMIDE-PEG1-CO2H Pomalidomide-O-C4-NH2 Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]- Pomalidomide-PEG3-N3 Pomalidomide-PEG6-butyl iodide Pomalidomide-NH-PEG2-azide Pomalidomide-NH-PEG6-azide Pomalidomide-NH-PEG1-azide Pomalidomide-NH-PEG5-azide

Pomalidomide-PEG4-azide

Pomalidomide-NH-?PEG4-?azide

4-((14-azido-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

14-Azido-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-3,6,9,12-tetraoxatetradecanamide, Crosslinker-E3 ligase ligand conjugate, Pomalidomide conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader

Pomalidomide-PEG?-Azide

2271036-47-4