ChemicalBook > CAS DataBase List > Propargyl-PEG4-acid

Propargyl-PEG4-acid

Product Name
Propargyl-PEG4-acid
CAS No.
1415800-32-6
Chemical Name
Propargyl-PEG4-acid
Synonyms
Alkyne-PEG4-COOH;PROPARGYL-PEG4-COOH;Propargyl-PEG4-acid;Propargyl-PEG3-C2-COOH;Propargyl-PEG4-CH2CO2H;Propyne-PEG3-CH2CH2COOH;Propargyl-PEG3-CH2CH2COOH;4,7,10,13-tetraoxahexadec-15-ynoic acid;4,7,10,13-Tetraoxahexadec-15-yn-1-oic acid;3-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]propanoic acid
CBNumber
CB83048731
Molecular Formula
C12H20O6
Formula Weight
260.28
MOL File
1415800-32-6.mol
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Propargyl-PEG4-acid Property

Boiling point:
388.0±37.0 °C(Predicted)
Density 
1.129±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in Water, DMSO, DCM, DMF
pka
4.28±0.10(Predicted)
form 
Viscous Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H242Heating may cause a fire

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P234Keep only in original container.

P235Keep cool.

P240Ground/bond container and receiving equipment.

P370+P378In case of fire: Use … for extinction.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
902543
Product name
Propargyl-PEG4-acid
Packaging
250MG
Price
$117.2
Updated
2024/03/01
Sigma-Aldrich
Product number
902543
Product name
Propargyl-PEG4-acid
Packaging
1G
Price
$1070
Updated
2023/06/20
TRC
Product number
P839603
Product name
Propargyl-PEG4-acid
Packaging
100mg
Price
$265
Updated
2021/12/16
Activate Scientific
Product number
AS103922
Product name
Propargyl-PEG3-CH2CH2COOH
Purity
95+%
Packaging
5G
Price
$1286
Updated
2021/12/16
BroadPharm
Product number
BP-21094
Product name
Propargyl-PEG4-acid
Purity
98%
Packaging
250mg
Price
$360
Updated
2021/12/16
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Propargyl-PEG4-acid Chemical Properties,Usage,Production

Description

Propargyl-PEG4-acid is a PEG reagent with an alkyne and a terminal carboxylic acid. The carboxylic acid reacts with primary amine groups with the help of activators (e.g. EDC, or HATU). The 4-unit PEG spacer increases hydrophilicity. The alkyne can participate in copper-catalyzed Click Chemistry.

Uses

This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG4-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

Propargyl-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Propargyl-PEG4-acid manufacturers

Henan Fengda Chemical Co., Ltd
Product
Propargyl-PEG4-acid 1415800-32-6
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-27
Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG4-acid 1415800-32-6
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-26
Career Henan Chemical Co
Product
Propargyl-PEG4-acid 1415800-32-6
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2020-03-23

1415800-32-6, Propargyl-PEG4-acidRelated Search:


  • Propargyl-PEG4-acid
  • Propargyl-PEG4-CH2CO2H
  • Propyne-PEG3-CH2CH2COOH
  • Alkyne-PEG4-COOH
  • PROPARGYL-PEG4-COOH
  • Propargyl-PEG3-CH2CH2COOH
  • 4,7,10,13-tetraoxahexadec-15-ynoic acid
  • 4,7,10,13-Tetraoxahexadec-15-yn-1-oic acid
  • Propargyl-PEG3-CH2CH2COOH/4,7,10,13-Tetraoxahexadec-15-ynoic acid
  • Propargyl-PEG3-C2-COOH
  • 3-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]propanoic acid
  • 1415800-32-6
  • 5800-32-6
  • peg