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Propargyl-PEG4-acid

Product Name
Propargyl-PEG4-acid
CAS No.
1415800-32-6
Chemical Name
Propargyl-PEG4-acid
Synonyms
Alkyne-PEG4-COOH;PROPARGYL-PEG4-COOH;Propargyl-PEG4-acid;Propargyl-PEG3-C2-COOH;Propargyl-PEG4-CH2CO2H;Propyne-PEG3-CH2CH2COOH;Propargyl-PEG3-CH2CH2COOH;4,7,10,13-tetraoxahexadec-15-ynoic acid;4,7,10,13-Tetraoxahexadec-15-yn-1-oic acid;3-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]propanoic acid
CBNumber
CB83048731
Molecular Formula
C12H20O6
Formula Weight
260.28
MOL File
1415800-32-6.mol
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Propargyl-PEG4-acid Property

Boiling point:
388.0±37.0 °C(Predicted)
Density 
1.129±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in Water, DMSO, DCM, DMF
pka
4.28±0.10(Predicted)
form 
Viscous Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H242Heating may cause a fire

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P234Keep only in original container.

P235Keep cool.

P240Ground/bond container and receiving equipment.

P370+P378In case of fire: Use … for extinction.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
902543
Product name
Propargyl-PEG4-acid
Packaging
250MG
Price
$117.2
Updated
2024/03/01
Sigma-Aldrich
Product number
902543
Product name
Propargyl-PEG4-acid
Packaging
1G
Price
$1070
Updated
2023/06/20
TRC
Product number
P839603
Product name
Propargyl-PEG4-acid
Packaging
100mg
Price
$265
Updated
2021/12/16
BroadPharm
Product number
BP-21094
Product name
Propargyl-PEG4-acid
Purity
98%
Packaging
250mg
Price
$360
Updated
2021/12/16
Activate Scientific
Product number
AS103922
Product name
Propargyl-PEG3-CH2CH2COOH
Purity
95+%
Packaging
1g
Price
$431
Updated
2021/12/16
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Propargyl-PEG4-acid Chemical Properties,Usage,Production

Description

Propargyl-PEG4-acid is a PEG reagent with an alkyne and a terminal carboxylic acid. The carboxylic acid reacts with primary amine groups with the help of activators (e.g. EDC, or HATU). The 4-unit PEG spacer increases hydrophilicity. The alkyne can participate in copper-catalyzed Click Chemistry.

Uses

This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG4-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

Propargyl-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG4-acid Suppliers

T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5873
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
9996
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28806
Advantage
58
Hangzhou HanLai Biochemical Technology Co., Ltd.
Tel
571-86101219 18768477782
Fax
-
Email
sales09@leobiochem.com
Country
China
ProdList
433
Advantage
58
Aikon International Limited
Tel
025-66028182 18112977050
Fax
(3)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
15818
Advantage
58
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View Lastest Price from Propargyl-PEG4-acid manufacturers

Henan Fengda Chemical Co., Ltd
Product
Propargyl-PEG4-acid 1415800-32-6
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-27
Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG4-acid 1415800-32-6
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-26
Career Henan Chemical Co
Product
Propargyl-PEG4-acid 1415800-32-6
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2020-03-23

1415800-32-6, Propargyl-PEG4-acidRelated Search:


  • Propargyl-PEG4-acid
  • Propargyl-PEG4-CH2CO2H
  • Propyne-PEG3-CH2CH2COOH
  • Alkyne-PEG4-COOH
  • PROPARGYL-PEG4-COOH
  • Propargyl-PEG3-CH2CH2COOH
  • 4,7,10,13-tetraoxahexadec-15-ynoic acid
  • 4,7,10,13-Tetraoxahexadec-15-yn-1-oic acid
  • Propargyl-PEG3-CH2CH2COOH/4,7,10,13-Tetraoxahexadec-15-ynoic acid
  • Propargyl-PEG3-C2-COOH
  • 3-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]propanoic acid
  • 1415800-32-6
  • 5800-32-6
  • peg