Propargyl-PEG4-acid
- Product Name
- Propargyl-PEG4-acid
- CAS No.
- 1415800-32-6
- Chemical Name
- Propargyl-PEG4-acid
- Synonyms
- Alkyne-PEG4-COOH;PROPARGYL-PEG4-COOH;Propargyl-PEG4-acid;Propargyl-PEG3-C2-COOH;Propargyl-PEG4-CH2CO2H;Propyne-PEG3-CH2CH2COOH;Propargyl-PEG3-CH2CH2COOH;4,7,10,13-tetraoxahexadec-15-ynoic acid;4,7,10,13-Tetraoxahexadec-15-yn-1-oic acid;Propargyl-PEG3-CH2CH2COOH/4,7,10,13-Tetraoxahexadec-15-ynoic acid
- CBNumber
- CB83048731
- Molecular Formula
- C12H20O6
- Formula Weight
- 260.28
- MOL File
- 1415800-32-6.mol
Propargyl-PEG4-acid Property
- Boiling point:
- 388.0±37.0 °C(Predicted)
- Density
- 1.129±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble in Water, DMSO, DCM, DMF
- pka
- 4.28±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H242Heating may cause a fire
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P234Keep only in original container.
P235Keep cool.
P240Ground/bond container and receiving equipment.
P370+P378In case of fire: Use … for extinction.
P403Store in a well-ventilated place.
N-Bromosuccinimide Price
- Product number
- 902543
- Product name
- Propargyl-PEG4-acid
- Packaging
- 250MG
- Price
- $117.2
- Updated
- 2024/03/01
- Product number
- 902543
- Product name
- Propargyl-PEG4-acid
- Packaging
- 1G
- Price
- $1070
- Updated
- 2023/06/20
- Product number
- P839603
- Product name
- Propargyl-PEG4-acid
- Packaging
- 100mg
- Price
- $265
- Updated
- 2021/12/16
- Product number
- AS103922
- Product name
- Propargyl-PEG3-CH2CH2COOH
- Purity
- 95+%
- Packaging
- 5G
- Price
- $1286
- Updated
- 2021/12/16
- Product number
- BP-21094
- Product name
- Propargyl-PEG4-acid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $360
- Updated
- 2021/12/16
Propargyl-PEG4-acid Chemical Properties,Usage,Production
Description
Propargyl-PEG4-acid is a PEG reagent with an alkyne and a terminal carboxylic acid. The carboxylic acid reacts with primary amine groups with the help of activators (e.g. EDC, or HATU). The 4-unit PEG spacer increases hydrophilicity. The alkyne can participate in copper-catalyzed Click Chemistry.
Uses
This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG4-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
Propargyl-PEG4-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG4-acid Suppliers
View Lastest Price from Propargyl-PEG4-acid manufacturers
- Product
- Propargyl-PEG4-acid 1415800-32-6
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-27
- Product
- Propargyl-PEG4-acid 1415800-32-6
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-26
- Product
- Propargyl-PEG4-acid 1415800-32-6
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2020-03-23