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5-BROMO-2-(METHYLTHIO)PYRIMIDINE

Product Name
5-BROMO-2-(METHYLTHIO)PYRIMIDINE
CAS No.
14001-67-3
Chemical Name
5-BROMO-2-(METHYLTHIO)PYRIMIDINE
Synonyms
5-BROMO-2-(METHYLTHIO)PYRIMIDINE;5-BROMO-2-METHYLSULFANYLPYRIMIDINE;2-Methylsulfanyl-5-broMopyriMidine;5-broMo-2-MethylpyriMidine-1-thiol;Pyrimidine, 5-bromo-2-(methylthio)-;5-Bromo-2-(methylthio)pyrimidine ,98%;5-BROMO-2-(METHYLTHIO)PYRIMIDINE ISO 9001：2015 REACH;5-BroMo-2-(Methylthio)pyriMidine
CBNumber
CB8452506
Molecular Formula
C5H5BrN2S
Formula Weight
205.08
MOL File
14001-67-3.mol
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5-BROMO-2-(METHYLTHIO)PYRIMIDINE Property

Melting point:
63-68℃
Boiling point:
281.2±13.0 °C(Predicted)
Density 
1.72±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
pka
-0.56±0.22(Predicted)
form 
Crystalline Powder of Flakes
color 
White
InChI
InChI=1S/C5H5BrN2S/c1-9-5-7-2-4(6)3-8-5/h2-3H,1H3
InChIKey
WFLSPLBDSJLPFW-UHFFFAOYSA-N
SMILES
C1(SC)=NC=C(Br)C=N1
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Safety

Hazard Codes 
Xi,Xn,C
Risk Statements 
22-34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 1759 8/PG 2
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
8
PackingGroup 
Ⅱ
HS Code 
29335995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
705896
Product name
5-Bromo-2-(methylthio)pyrimidine
Purity
97%
Packaging
1g
Price
$79.7
Updated
2022/05/15
TRC
Product number
B697830
Product name
5-Bromo-2-(methylthio)pyrimidine
Packaging
250mg
Price
$55
Updated
2021/12/16
TRC
Product number
B697830
Product name
5-Bromo-2-(methylthio)pyrimidine
Packaging
500mg
Price
$65
Updated
2021/12/16
Matrix Scientific
Product number
069495
Product name
5-Bromo-2-(methylthio)pyrimidine
Purity
98%
Packaging
5g
Price
$78
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB139356
Product name
5-Bromo-2-(methylthio)pyrimidine
Packaging
5G
Price
$79
Updated
2021/12/16
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5-BROMO-2-(METHYLTHIO)PYRIMIDINE Chemical Properties,Usage,Production

Synthesis

74-93-1

32779-36-5

14001-67-3

Step 1: Synthesis of 5-bromo-2-methylmercaptopyrimidine To a stirred solution of 5-bromo-2-chloropyrimidine (0.3 g, 1.563 mmol) in dimethylformamide (DMF, 10 mL) was slowly added methyl mercaptan (0.1 mL, 1.563 mmol) at room temperature. The reaction mixture was then heated to 50 °C with continuous stirring for 3 hours. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was quenched by addition of water and extracted with ethyl acetate (EtOAc). The organic phases were combined and dried over anhydrous sodium sulfate (Na2SO4), followed by evaporation of the solvent under reduced pressure to give the crude product. The crude product was purified by silica gel (100-200 mesh) column chromatography using 5% ethyl acetate/hexane as eluent, resulting in purified 5-bromo-2-methylmercaptopyrimidine (0.240 g, 75% yield) as a white solid. Mass spectrometry (MS) analysis showed that [M++1] was 205.1.

References

[1] Patent: US2017/291910, 2017, A1. Location in patent: Paragraph 0496-0498

5-BROMO-2-(METHYLTHIO)PYRIMIDINE Preparation Products And Raw materials

Raw materials

ZINC Phosphorus oxitrichloride Carbon tetrachloride 2-Methylthio-4-pyrimidinol Bromine

Preparation Products

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5-BROMO-2-(METHYLTHIO)PYRIMIDINE Suppliers

China 114 Germany 2 India 1 United Kingdom 3 United States 16 Global 136
NovoChemy Ltd.
Tel
021-31261262/ 49 (0)17662837245
Fax
(0)21-33250524
Email
sales@novochemy.com
Country
Germany
ProdList
6328
Advantage
58
ACTIVATE SCIENTIFIC GmbH
Tel
--
Fax
--
Email
info@activate-scientific.com
Country
Germany
ProdList
2856
Advantage
61
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View Lastest Price from 5-BROMO-2-(METHYLTHIO)PYRIMIDINE manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
5-Bromo-2-(methylthio)pyrimidine 14001-67-3
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-11-13
Shanghai Rlavie Technology Co ltd
Product
5-Bromo-2-(methylthio)pyrimidine 14001-67-3
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%minHPLC
Supply Ability
100kgs/month
Release date
2021-11-17
Dideu Industries Group Limited
Product
5-BROMO-2-(METHYLTHIO)PYRIMIDINE 14001-67-3
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-01

14001-67-3, 5-BROMO-2-(METHYLTHIO)PYRIMIDINERelated Search:

5-Bromo-2-methylpyridine 5-Bromo-2-hydroxymethylpyridine 5-Bromo-2-methoxypyridine 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE 4-Bromo-2-(methylthio)pyrimidine 5-BROMO-2-(METHYLTHIO)PYRIMIDINE-4-CARBOXYLIC ACID,5-BROMO-2-(METHYLTHIO)PYRIMIDINE-4-CARB&,5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid ,97% Methyl 5-bromo-2-(methylthio)pyrimidine-4-carboxylate ,97% 5-BROMO-2-(METHYLTHIO)PYRIMIDINE 5-BROMO-2-METHANESULFONYL-PYRIMIDINE 6-AMINO-5-BROMO-2-(ETHYLTHIO)PYRIMIDIN-4-OL 5-bromo-2-(methylsulfanyl)pyrimidin-4-ol 4-[(5-BROMOPYRIMIDIN-2-YL)THIO]ANILINE ((5-BROMOPYRIMIDIN-2-YL)THIO)ACETIC ACID 2-[(5-BROMOPYRIMIDIN-2-YL)THIO]ANILINE IFLAB-BB F2124-0044 5-Bromo-4-methoxy-2-(methylthio)pyrimidine METHYL [(5-BROMO-4-HYDROXY-6-METHYLPYRIMIDIN-2-YL)THIO]ACETATE 2-(2-thenyl)sulfonyl-5-bromopyrimidine

  • 5-BROMO-2-METHYLSULFANYLPYRIMIDINE
  • 5-BROMO-2-(METHYLTHIO)PYRIMIDINE
  • 5-Bromo-2-(methylthio)pyrimidine ,98%
  • 5-broMo-2-MethylpyriMidine-1-thiol
  • 2-Methylsulfanyl-5-broMopyriMidine
  • 5-<WBR>BroMo-<WBR>2-<WBR>(Methylthio)<WBR>pyriMidine
  • Pyrimidine, 5-bromo-2-(methylthio)-
  • 5-BROMO-2-(METHYLTHIO)PYRIMIDINE ISO 9001：2015 REACH
  • 14001-67-3
  • C5H5BrN2S
  • Building Blocks
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyrimidines
  • Heterocycle-Pyrimidine series
  • Pyrimidine
  • Organohalides
  • Thio