ChemicalBook > CAS DataBase List > PROTAC IRAK4 degrader-1
PROTAC IRAK4 degrader-1
- Product Name
- PROTAC IRAK4 degrader-1
- CAS No.
- 2360533-90-8
- Chemical Name
- PROTAC IRAK4 degrader-1
- Synonyms
- PROTAC IRAK4 degrader-1;2-{2-[(cyclopropylmethyl)amino]pyridin-4-yl}-N-{1-[4-({3-[4-({[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}methyl)-1H-imidazol-1-yl]propyl}carbamoyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-4-yl}-1,3-oxazole-4-carboxamide
- CBNumber
- CB88054605
- Molecular Formula
- C44H39F3N12O7
- Formula Weight
- 904.85
- MOL File
- Mol file
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PROTAC IRAK4 degrader-1 Property
- Density
- 1.61±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- pka
- 10.74±0.40(Predicted)
- form
- Solid
- color
- White to yellow
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PROTAC IRAK4 degrader-1 Chemical Properties,Usage,Production
Biological Activity
PROTAC IRAK4 degrader-1 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1 Compound I-210, makes 20-50%, and >50% IRAK4 degradation at 0.01, 0.1, and 1 μM in OCI-LY-10 cells, respectively[1].
References
[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.
PROTAC IRAK4 degrader-1 Preparation Products And Raw materials
Raw materials
Preparation Products
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PROTAC IRAK4 degrader-1 Suppliers
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32165
- Advantage
- 58
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