ChemicalBook > CAS DataBase List > Isopropylamine

Isopropylamine

Product Name
Isopropylamine
CAS No.
75-31-0
Chemical Name
Isopropylamine
Synonyms
MIPA;MONOISOPROPYLAMINE;2-Propanamine;2-Propylamine;Isopropylamine Anhydrous;sopropylamine;MIPA-70;nsc62775;iso-C3H7NH2;i-Propylamin
CBNumber
CB8854223
Molecular Formula
C3H9N
Formula Weight
59.11
MOL File
75-31-0.mol
More
Less

Isopropylamine Property

Melting point:
-101 °C
Boiling point:
32-35 °C 33-34 °C (lit.)
Density 
0.688 g/mL at 20 °C (lit.)
vapor density 
2.04 (vs air)
vapor pressure 
9.2 psi ( 20 °C)
refractive index 
n20/D 1.374(lit.)
FEMA 
4238 | ISOPROPYLAMINE
Flash point:
−26 °F
storage temp. 
2-8°C
solubility 
1000g/l
form 
Crystalline Powder, Needles or Crystals
pka
10.63(at 25℃)
color 
APHA: ≤50
PH
13 (700g/l, H2O, 20℃)
Odor
Strong ammoniacal; pungent, irritating, typical amine.
Odor Threshold
0.025ppm
Odor Type
fishy
explosive limit
2-10.4%(V)
Water Solubility 
soluble
Sensitive 
Air Sensitive
JECFA Number
1581
Merck 
14,5209
BRN 
605259
Exposure limits
TLV-TWA 5 ppm (～12 mg/m3) (ACGIH, MSHA, and OSHA); TLV-STEL 10 ppm(～24 mg/m3) (ACGIH); IDLH 4000 ppm (NIOSH).
Dielectric constant
5.5（20℃）
Stability:
Stable. Extremely flammable - note low boiling point and low flash point. Readily forms explosive mixtures with air. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, perchloryl fluoride.
LogP
0.21
CAS DataBase Reference
75-31-0(CAS DataBase Reference)
NIST Chemistry Reference
2-Propanamine(75-31-0)
EPA Substance Registry System
Isopropylamine (75-31-0)
More
Less

Safety

Hazard Codes 
F+,Xi,T
Risk Statements 
12-36/37/38-37-35-25-20/21
Safety Statements 
16-26-29-45-36/37/39
RIDADR 
UN 1221 3/PG 1
WGK Germany 
1
RTECS 
NT8400000
F 
34
Autoignition Temperature
755 °F
TSCA 
Yes
HS Code 
2921 19 99
HazardClass 
3
PackingGroup 
I
Hazardous Substances Data
75-31-0(Hazardous Substances Data)
Toxicity
LD50 orally in rats: 820 mg/kg (Smyth)
IDLA
750 ppm
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H224Extremely flammable liquid and vapour

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.07476
Product name
Isopropylamine
Purity
for synthesis
Packaging
100mL
Price
$34.5
Updated
2024/03/01
Sigma-Aldrich
Product number
8.07476
Product name
Isopropylamine
Purity
for synthesis
Packaging
1L
Price
$60.4
Updated
2024/03/01
Sigma-Aldrich
Product number
8.07476
Product name
Isopropylamine
Purity
for synthesis
Packaging
2.5L
Price
$118
Updated
2024/03/01
Sigma-Aldrich
Product number
471291
Product name
Isopropylamine
Purity
≥99.5%
Packaging
1l
Price
$47.9
Updated
2024/03/01
Sigma-Aldrich
Product number
471291
Product name
Isopropylamine
Purity
≥99.5%
Packaging
2l
Price
$74.5
Updated
2024/03/01
More
Less

Isopropylamine Chemical Properties,Usage,Production

Description

Isopropylamine (propan-2-amine, IUPAC) is a colorless, volatile liquid. It is highly flammable, with a flammable range of 2%–10.4% in air. Boiling point is 93°F (33°C), flash point is ?15°F (?26°C), and ignition temperature is 756°F (402°C).
It is miscible with water, with a specific gravity of 0.69, which is lighter than water. Vapor density is 2.04, which is heavier than air. In addition to flammability, isopropylamine is a strong irritant to tissue and has a TLV of 5 ppm in air. The four-digit UN identification number is 1221. The NFPA 704 designation for isopropylamine is health 3, flammability 4, and reactivity 0. Primary uses for isopropylamine are pharmaceuticals, dyes, insecticides, and as a dehairing agent.

Chemical Properties

Isopropylamine is a colorless, flammable liquid. Isopropylamine is miscible with water, alcohol, and ether.The odor threshold reportedly ranges from 0.21 to 0.70 ppm; the pungent, ammoniacal odor becomes irritating at 24mg/m3 (110).

Physical properties

Colorless liquid with a penetrating, ammonia-like odor. Experimentally determined detection and recognition odor threshold concentrations were 500 μg/m3 (210 ppbv) and 1.7 mg/m3 (700 ppbv), respectively (Hellman and Small, 1974). An odor threshold concentration of 25 ppbv was reported by Nagata and Takeuchi (1990).

Occurrence

Not reported found in natu

Uses

Isopropylamine is an organic compound is a widely used for the synthesis of pharmaceutical and agricultural goods such as glyphosphate herbicides and as an additive for petroleum industry. such as bentazon (BASF), Roundup (Monsanto), imazapyr (ACC) and the triazines ametryne (Novartis), atrazine (Novartis), desmetryn (Novartis), prometryn (Novartis), pramitol (Novartis), dipropetryn (Novartis), and propazine. Other applications encompass the nematicide fenamiphos (Bayer), the fungicide iprodione (Rho?ne-Poulenc), insecticides, pharmaceuticals, and surfactants.

Uses

Isopropylamine is used as a dehairing agentand as an intermediate in the preparation ofmany organics.

Uses

Solvent, intermediate in synthesis of rubber accelerators, pharmaceuticals, dyes, insecticides, bactericides, textile specialties, and surface-active agents, dehairing agent, solubilizer for 2,4-D acid.

Production Methods

Isopropylamine can be produced from the corresponding alcohol by reacting with ammonia in the presence of a dehydrating catalyst, or from the chloride by reacting with ammonia under pressure. It is also reported that this amine can be produced from acetone and ammonia or from the acetone oxime (HSDB 1989).

Definition

ChEBI: A member of the class of alkylamines that is propane carrying an amino group at position 2.

Aroma threshold values

High strength odor; fishy type; recommend smelling in a 0.10% solution or less.

General Description

A clear colorless liquid with an ammonia-like odor. Flash point -35°F. Boiling point 90°F. Less dense than water Vapors heavier than air. Produces toxic oxides of nitrogen during combustion. Used as a solvent and to make other chemicals.

Air & Water Reactions

Highly flammable. Water soluble.

Reactivity Profile

Isopropylamine is a colorless, alkaline liquid, very volatile, moderately toxic, highly flammable. Dangerous fire hazard when exposed to heat, flame, sparks, or strong oxidizers. When heated to decomposition Isopropylamine emits toxic fumes of oxides of nitrogen [M. K.]. A mixture of Isopropylamine and perchloryl fluoride resulted in an uncontrolled oxidation and/or explosion, [J. Org. Chem., 1980, 45, 4036]. The reaction of 1-chloro-2,3-epoxypropane and the amine and most probably other nitrogen bases, yields a violent exotherm, [Chem. & Ind., 1971, 994].

Hazard

Highly flammable, dangerous fire risk. Strong irritant to tissue.

Health Hazard

Isopropylamine is a strong irritant to theeyes, skin, and respiratory system. A shortexposure to 10–20 ppm can cause irritationof the nose and throat in humans (Procturand Hughes 1978). Prolonged exposure tohigh concentrations may lead to pulmonaryedema. Skin contact can cause dermatitisand skin burns. Exposure to 8000 ppm for4 hours was lethal to rats.
LD50 value, oral (mice): 2200 mg/kg.

Chemical Reactivity

Reactivity with Water No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Industrial uses

Isopropylamine can be used as a dehairing agent and as a solvent. It also finds use as an intermediate in the production of insecticides, herbicides and bactericides and in the production of pharmaceuticals, dyes and rubber accelerators (HSDB 1989).

Environmental Fate

Photolytic. Low et al. (1991) reported that the photooxidation of aqueous primary amine solutions by UV light in the presence of titanium dioxide resulted in the formation of ammonium and nitrate ions.
Chemical/Physical. Releases toxic nitrogen oxides when heated to decomposition (Sax and Lewis, 1987). Forms water-soluble salts with acids.

Metabolism

One would expect isopropylamine to be readily absorbed from the gut and respiratory tract. Shorter chain aliphatic amines such as isopropylamine also are efficiently absorbed through the skin (Beard and Noe 1981). When administered intravenously, isopropylamine distributed rapidly into tissue compartments with tissue/plasma ratios ranging from 1.8 in the atrium to 16.7 in the renal medulla (Privitera et al 1982). During the elimination phase, a half-life of 146 min was observed in plasma. There do not appear to be any definitive metabolic studies with this compound, however through a comparison with other substrates, one might expect oxidation to acetone and ammonia through the action of monoamine oxidase (Tipton 1980).

Isopropylamine Preparation Products And Raw materials

Raw materials

Acetone Nickel aluMinuM Barium hydroxide Diisopropylamine KAOLIN Isopropyl alcohol Ammonia

Preparation Products

Befunolol N-T-BUTYL-N'-ISOPROPYLTHIOUREA Solvent Blue 36 DIPROPETRYN CARAZOLOL HCL Prometryn 1-Isopropyl-4-piperidone (-)-2-BETA-CARBOMETHOXY-3-BETA-(4-FLUOROPHENYL)TROPANE N-Isopropylacrylamide Orciprenaline N-ISOPROPYLNORTROPINYL A HYDROXYMETHYL)PHENYLACETATE Ethyl 3-(isopropylamino)propanoate N-(2-METHOXYETHYL)METHYLAMINE Ametryn Pindolol Propyl isocyanate Nilutamide 1-ISOPROPYL-5-HYDROXYPYRAZOL 2-BROMO-3-FORMYLPYRIDINE ISOFENPHOS-METHYL U-47319 Buprofezin 3-MORPHOLIN-4-YL-PROPIONIC ACID 8-isopropyl-8-azabicyclo[3.2.1]oct-3-yl endo-(±)-formylphenylacetate Diisopropylamine 4-(BROMOMETHYL)-N-(L-METHYLETHYL)BENZAMIDE AMIPROFOS METHYL Atrazine ISOFENPHOS Iprodione Fenamiphos Bentazone 4-(4-(Chlorophenyl)imino)-1-isopropyl piperidine Lorcainide Clorprenaline N-(4-chlorophenyl)-1-isopropylpiperidin-4-amine 1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino]ethan-1-one
More
Less

Isopropylamine Suppliers

Americas 1 Australia 2 Belgium 5 Canada 2 Chile 1 China 250 Denmark 1 Europe 4 France 2 Germany 15 Hungary 1 India 72 Japan 6 Malaysia 1 Mexico 1 Poland 1 Russia 2 Slovakia 1 South Korea 2 Spain 3 Switzerland 2 The Netherlands 3 Ukraine 1 United Kingdom 13 United States 62 Global 454
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
CovaChem, LLC.
Tel
+1815.714.8421 (direct)
Fax
+1815.315.1272
Email
tonynooner@covachem.com
Country
United States
ProdList
89
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10404
Advantage
58
Protheragen-ING
Tel
+16313385890
Email
info@protheragen-ing.com
Country
United States
ProdList
3868
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
Frontier Scientific Services, Inc.
Tel
--
Fax
--
Email
customerservice@frontierssi.com
Country
United States
ProdList
1575
Advantage
0
Veckridge Chemical Co., Inc.
Tel
--
Fax
--
Email
info@veckridge.com
Country
United States
ProdList
184
Advantage
58
Neuchem
Tel
--
Fax
--
Email
INFO@NEUCHEM.COM
Country
United States
ProdList
256
Advantage
58
Scandinavian Formulas
Tel
--
Fax
--
Email
mikep@scandinavianformulas.com
Country
United States
ProdList
1550
Advantage
58
DAXX Chemical
Tel
--
Fax
--
Email
usa@daxxgrp.com
Country
United States
ProdList
79
Advantage
58
Coyne Chemical
Tel
--
Fax
--
Email
csr@coynechemical.com
Country
United States
ProdList
82
Advantage
58
Norman, Fox & Co.
Tel
--
Fax
--
Email
info@norfoxchem.com
Country
United States
ProdList
30
Advantage
58
Tilley Chemical Co., Inc.
Tel
--
Fax
--
Email
orders@tilleychem.com
Country
United States
ProdList
60
Advantage
58
First Intercontinental Corporation - FIC
Tel
--
Fax
--
Email
info@fic-usa.com
Country
United States
ProdList
21
Advantage
58
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United States
ProdList
4583
Advantage
58
Brenntag North America, Inc.
Tel
--
Fax
--
Email
bnereadingcs@brenntag.com
Country
United States
ProdList
211
Advantage
58
Brown Chemical Co., Inc.
Tel
--
Fax
--
Email
sharon.oreilly@brownchem.com
Country
United States
ProdList
51
Advantage
58
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
Veckridge Chemical
Tel
--
Fax
--
Email
rv@veckridge.com
Country
United States
ProdList
87
Advantage
58
BASF Corporation
Tel
--
Fax
--
Country
United States
ProdList
573
Advantage
86
MilliporeSigma (Sigma-Aldrich Corp.)
Tel
--
Fax
--
Email
@sial.com
Country
United States
ProdList
5414
Advantage
58
MP Biomedicals, LLC. (Division of Valiant FC Co., Ltd.)
Tel
--
Fax
--
Email
serv@mpbio.com
Country
United States
ProdList
1854
Advantage
58
Eastman AgChem Intermediates (Eastman Chemical Company)
Tel
--
Fax
--
Country
United States
ProdList
21
Advantage
58
Aozeal Certified Standards (AOCS), Inc.
Tel
--
Fax
--
Email
info@aozeal.com
Country
United States
ProdList
504
Advantage
58
CALSAK CORPORATION
Tel
--
Fax
--
Email
calsak@calsak.com
Country
United States
ProdList
430
Advantage
58
Penta Manufacturing Company (a division of Penta International Corporation)
Tel
--
Fax
--
Email
@pentamfg.com
Country
United States
ProdList
901
Advantage
58
Lowe Chemical Co.
Tel
--
Fax
--
Country
United States
ProdList
15
Advantage
58
U. S. Amines Limited
Tel
--
Fax
--
Email
gmerkel@usamines.com
Country
United States
ProdList
10
Advantage
58
Univar Solutions Inc.
Tel
--
Fax
--
Email
sherry.uong@univar.com
Country
United States
ProdList
55
Advantage
58
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
TCI America, Inc. (part of Tokyo Chemical Industry)
Tel
--
Fax
--
Email
Angelina.Crew@tcichemicals.com
Country
United States
ProdList
2053
Advantage
58
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Eastman Chemical Company
Tel
--
Fax
--
Country
United States
ProdList
814
Advantage
81
Penta International Corporation
Tel
--
Fax
--
Email
lisaa@pentamfg.com
Country
United States
ProdList
5042
Advantage
58
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
ASDI Incorporated
Tel
--
Fax
--
Email
customerservice@asdi.net
Country
United States
ProdList
6922
Advantage
67
Chemstock Inc.
Tel
--
Fax
--
Email
mail@chemstock.com
Country
United States
ProdList
575
Advantage
34
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Penta Manufacturing Company
Tel
--
Fax
--
Email
sales@pentamfg.com
Country
United States
ProdList
5076
Advantage
65
Pfaltz & Bauer, Inc.
Tel
--
Fax
--
Email
sales@pfaltzandbauer.com
Country
United States
ProdList
6828
Advantage
72
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
Leonid Chemicals Private Limited
Tel
--
Fax
--
Email
careers@leonidchemicals.com
Country
United States
ProdList
1700
Advantage
43
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
Naugra Export
Tel
--
Fax
--
Country
United States
ProdList
1332
Advantage
47
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
Arkema Inc.
Tel
--
Fax
--
Email
dave.seiler@arkemagroup.com
Country
United States
ProdList
82
Advantage
30
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
City Chemical LLC
Tel
--
Fax
--
Email
sales@citychemical.com
Country
United States
ProdList
6708
Advantage
72
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
More
Less

View Lastest Price from Isopropylamine manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Isopropylamine 75-31-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-01
Hebei Mojin Biotechnology Co.,Ltd
Product
Isopropylamine 75-31-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-05-23
Hebei Mojin Biotechnology Co., Ltd
Product
Isopropylamine 75-31-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-22

75-31-0, IsopropylamineRelated Search:

Diethylamine Glucosamine Pyrimethamine N,N-Dimethylethylamine Epichlorohydrin Etamsylate EC 2.6.1.2 Trimethylolpropane Propylamine L-1-Phenylethylamine Ethambutol Propylene oxide Sulfamic acid Triethylamine Acetaminophen Sodium propan-2-olate Isopropyl alcohol Amino-2-propanol

  • iso-C3H7NH2
  • Isopropilamina
  • Isopropylamin
  • iso-Propylamine gas
  • isopropylamine(2-aminopropane)
  • isopropylamine(non-specificname)
  • isopropylaminemethylnaphthalenesulfonate
  • nsc62775
  • Propane, 2-amino-
  • Propylamine mono
  • ISOPROPYLAMINE FOR SYNTHESIS 100 ML
  • ISOPROPYLAMINE FOR SYNTHESIS 2,5 L
  • ISOPROPYLAMINE FOR SYNTHESIS 1 L
  • MonoethylaMine (70% in Water)
  • MonoisopropylaMine(70% in Water)
  • Isopropylamine 99.7%
  • 1-Methylethylamine
  • 2-Amino-propaan
  • 2-Aminopropan
  • 2-amino-propan
  • 2-amino-propana
  • 2-Amino-propano
  • 2-propaneamine
  • 2-Propylamine
  • sec-propylamine
  • MONOISOPROPYLAMINE
  • MIPA
  • MIPA-70
  • ISOPROPYLAMINE
  • 2-Propanamine
  • PropyldamineatomD
  • MONOISOPROPYLAMINE (AIR PRODUCTS MIPA)
  • ISO-PROPYLAMINE ANHYDROUS, OEKANAL
  • ISOPROPYLAMINE, 99.5+%
  • #niso-Propylamine solution ca. 70 %
  • #niso-Propylamine
  • ISOPROPYLAMINE, 1000MG, NEAT
  • IsopropylamineForSynthesis
  • iso-Propyl-d7-amine, 99 atom % D
  • Isopropylamine,99+%
  • 2-AMINOPROPANE
  • i-Propylamin
  • Isopropylamine Anhydrous
  • IsopropylaMine, 99% 1LT
  • Monoisopropylamine70%
  • 2-aminopropane isopropylamine
  • 1-Methylethanamine
  • Propane-2-amine
  • sopropylamine
  • Isopropylamine&gt
  • Isopropylamine ISO 9001：2015 REACH
  • MINOISOPROPYLAMINE
  • MINOISOPROPYLAMINE(70%IN WATER)
  • Isopropylamine, GR 99%+
  • Isopropylamine (MIPA) extrapure, 99%
  • propan-2-amine Isopropylamine
  • SODIUM GLYCINATE 6000-44-8
  • 75-31-0