DMT-2μ-O-Me-rG(ib) amidite

Product Name: DMT-2μ-O-Me-rG(ib) amidite
CAS No.: 251647-55-9
Chemical Name: DMT-2μ-O-Me-rG(ib) amidite
Synonyms: DMT-2'-O-MOE-G(iBu)-CE;2’-MOE-dG(iBu) Amidite;DMT-2'-O-MOE-G(iBu)-CEP;DMT-2'-O-MOE-G(iBu)-CEP;DMT-2μ-O-Me-rG(ib) amidite;N2-iBu-5'-O-DMT-2'-O-MOE-G-CE;2'-O-MOE-ibu-G Phosphoramidite;2'-MOE-N-iBu Guanosine Amidite;2'-MOE-N-iBu Guanosine Amidite;2'-MOE-iBu-G CE Phosphoramidite
CBNumber: CB92092206
Molecular Formula: C47H60N7O10P
Formula Weight: 913.99
MOL File: 251647-55-9.mol

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DMT-2μ-O-Me-rG(ib) amidite Property

storage temp.: 4°C, protect from light
solubility: DMSO : 250 mg/mL (273.53 mM; Need ultrasonic)
form: Powder
pka: 9.16±0.20(Predicted)
color: White to Off-white
InChI: InChI=1/C47H60N7O10P/c1-30(2)43(55)51-46-50-42-39(44(56)52-46)49-29-53(42)45-41(60-27-26-57-7)40(64-65(62-25-13-24-48)54(31(3)4)32(5)6)38(63-45)28-61-47(33-14-11-10-12-15-33,34-16-20-36(58-8)21-17-34)35-18-22-37(59-9)23-19-35/h10-12,14-23,29-32,38,40-41,45H,13,25-28H2,1-9H3,(H2,50,51,52,55,56)/t38-,40-,41-,45-,65?/s3
InChIKey: LADCDGNEBIQAAU-KEFUZROQNA-N
SMILES: O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](OCCOC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,44,50,r|

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Alfa Aesar

Product number: J65100
Product name: 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-methylguanosine-3'-(2-cyanoethyl diisopropylphosphoramidite)
Purity: 98%
Packaging: 1g
Price: $65.65
Updated: 2024/03/01

TRC

Product number: D494268
Product name: 5''-O-DMT-N2-isobutyryl-2''-O-(2-methoxyethyl)-guanosine3''-CEphosphoramidite
Packaging: 500mg
Price: $330
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PD63448
Product name: 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite
Packaging: 2g
Price: $500
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: O108456
Product name: 5?-O-DMT-N2-isobutyryl-2?-O-(2-methoxyethyl)-guanosine3?-CEphosphoramidite
Packaging: 1g
Price: $675
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PD63448
Product name: 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite
Packaging: 250mg
Price: $90
Updated: 2021/12/16

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DMT-2μ-O-Me-rG(ib) amidite Chemical Properties,Usage,Production

Description

Nucleoside phosphoramidites are used in the synthesis of oligonucleotides. Using a chemical approach allows quick and inexpensive access to custom-made oligonucleotides of the desired sequence. Enzymatic synthesis proceeds in a 5’ to 3’ direction, however the chemical synthesis is usually performed in the opposite direction. 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite, also known as DMT-2μ-O-Me-rG(ib) amidite, is a modified guanosine with a 2’-O-(2-methoxyethyl) group, these have been used in the synthesis of oligonucleotides as antisense drugs.

Uses

5''-O-DMT-N2-isobutyryl-2''-O-(2-methoxyethyl)-guanosine 3''-CE phosphoramidite (CAS# 251647-55-9) is a nucleotide, and a derivative of guanosine, and is used in the stereochemical sythesis of phosphorothioate oligonucleotides.

storage

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

DMT-2μ-O-Me-rG(ib) amidite Preparation Products And Raw materials

Raw materials

Preparation Products

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DMT-2μ-O-Me-rG(ib) amidite Suppliers

China 111 India 2 Switzerland 1 United Kingdom 2 United States 4 Global 120

SIGMA-RBI

Tel: --
Fax: --
Country: Switzerland
ProdList: 6896
Advantage: 91

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View Lastest Price from DMT-2μ-O-Me-rG(ib) amidite manufacturers

Hefei Huana Biomedical Technology Co.,Ltd.

Product: N2-iBu-5'-O-DMT-2'-O-MOE-G-CE 251647-55-9
Price: US $0.00/mg
Min. Order: 100mg
Purity: ≥98%
Supply Ability: 20tons
Release date: 2023-03-09

SHANGHAI NOVRIBO BIOTECH

Product: 2'-MOE-iBu-G CE Phosphoramidite 251647-55-9
Price: US $100.00/kg
Min. Order: 0.009999999776482582kg
Purity: 99%
Supply Ability: 5tons
Release date: 2023-03-20

251647-55-9, DMT-2μ-O-Me-rG(ib) amiditeRelated Search:

2'-O-Methylcytidine 2’-O-Methyl-rA(N-Bz)phosphoramidite DMT-2′Fluoro-dU Phosphoramidite 2'-O-MOE-A(Bz)-3'-phosphoramidite 2'-O-(2-Methoxyethyl)-5-methyluridine N-blocked-5'-O-DMT-2'-O-Me CED cytosine phosphoramidite N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite Dmt-2'-f-dc(ac) amidite 2'-O-Methyladenosine 2'-O-(2-Methoxyethyl)cytidine 2'-O-Methylguanosine 2'-O-(2-Methoxyethyl)uridine DMT-2'-O-MOE-rU Phosphoramidite 2'-O-MOE-ADENOSINE 2'-OMe-ibu-G Phosphoramidite 2'-O-(2-Methoxyethyl)guanosine

DMT-2μ-O-Me-rG(ib) amidite

5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite

Guanosine, 5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-(2-Methoxyethyl)-N-(2-Methyl-1-oxopropyl)-, 3'-[2-cyanoethyl bis(1-Methylethyl)phosphoraMidite]

2'-MOE-G(iBu)-3'-phosphoramidite

5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-methylguanosine-3'-(2-cyanoethyl diisopropylphosphoramidite)

5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite

2'-O-MOE-G(iBu)-CE Phosphoramidite

GUANOSINE, 5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-(2-METHOXYETHYL)-N-(2-METHYL-1-OXOPROPYL)-, 3'-[2-CYANOETHYL BIS(1-METHYLETHYL)PHOSPHORAMIDITE] (9CI)

2'-O-MOE-ibu-G Phosphoramidite

DMT-2'-O-MOE-G(iBu)-CEP

DMT-2'-O-MOE-G(iBu)-CE-Phosphoramidite

N2-isobutyryl-5'-O-(4, 4'-dimethoxytrityl)-2'-O- methoxyethyl-guanosine-3'-cyanoethyl Phosphoramidite

Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

5’-O-(4,4’-Dimethoxy-trityl)-N2-iso-butyroyl-2’-O-(2-methoxyethyl)guanosine-3’-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphoramidite

5'-O-DMT-N2-isobutyryl-2'-O-?methoxyethylguanosine 3'-CE phosphoramidite

N2-isobutyryl-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite

2'-O-MOE-rG(ibu) Phosphoramidite

5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-N2-isobutyryl- guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

5'-O-DMT-2’-MOE-N2-iBu-Guanosine-CE-Phosphoramidite

DMT-2′O-MOE-rG(ib) Phosphoramidite

2’-MOE-G(iBu)-3’-phospho ramidite 5’-O-(4,4’-Dimethoxy-trityl)-N2-iso-butyroyl-2’-O-(2-methoxyethyl)guanosine-3’-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphoramidite

5'-O-DMT-2'-MOE-N2-Isobutyryl-Guanosine-CE Phosphoramidite

5’-O-DMTr-N2-iBu-2’-O-MOE-guanosine-3’-CED phosphoramidite

N2-iBu-5'-O-DMT-2'-O-MOE-G-CE

2'-MOE-iBu-G CE Phosphoramidite

5'-O-DMT-2'-O-MOE- N2-Isobutyryl- Guanosine -3’-Cyanoethyl Phosphoramidite

DMT-2'-O-MOE-G(iBu)-CE-PhosphoramiditeN2-isobutyryl-5'-O-(4,4'-dimethoxytri-tyl)-2'-O-methoxyethyl-guanosine-3'-cya-noethyl Phosphoramidite

2'-MOE-N-iBu Guanosine Amidite

DMT-2'-O-MOE-G(iBu)-CE

[5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N6-benzoyladenosin-3'-O-yl]-2-cyanoethyl-N,N-diisopropylphosphoramidite

DMTr-2'-O-MOE-rG(iBu)-3'-CE-Phosphoramidite

2’-MOE-dG(iBu) Amidite

Guanosine, 5-o-bis(4-methoxyphenyl)phenylmethyl-2-o-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3-2-cyanoethyl bis(1-

5’-O-(4, 4’-Dimethoxytrityl)-N2-isobutyryl-2’-O-(2-methoxyethyl)guanosine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

5'-ODMT-2'-OMOE-N-iBu Guanosine-3'-OCEPA

DMT-2'-O-MOE-G(iBu)-CE Phosphoramidite

2’-MOE-G(iBu)-3’-phosphoramidite

5'-O-DMT-2'-MOE-N2-Isobutyryl-Guanosine-CE Phosphoramidite

2'-MOE-iBu-G CE Phosphoramidite

2'-O-MOE-G(iBu)-CE-Phosphoramidite

5’-O-(4, 4’-Dimethoxytrityl)-N2-isobutyryl-2’-O-(2-methoxyethyl)guanosine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

[5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N6-benzoyladenosin-3'-O-yl]-2-cyanoethyl-N,N-diisopropylphosphoramidite

N2-iBu-2'-O-MOE-5'-O-DMT-G-3'-CE-Phosphoramidite

N-(9-[(2R,4R,5R)-5-[(bis(4-methoxyphenyl)(phenyl)methoxy)methyl]-4-{[(bis(propan-2-yl)amino)(2-cyanoethoxy)phosphanyl]oxy}-3-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-6,9-dihydro-5H-purin-2-yl)-2-methylpropanamide

2'-O-MOE-rG(ibu)Phosphoramidite

DMT-2'-O-MOE-G(iBu)-CEP

DMT-2'O-MOE-rG(ib) Phosphoramidite

N2-isobutyryl-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite

5'-O-DMT-2'-O-MOE- N2-Isobutyryl- Guanosine -3’-Cyanoethyl Phosphoramidite

5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite

2'-MOE-N-iBu Guanosine Amidite

251647-55-9

C47H60N7O10P

RNA Amidites

Sigma-Proligo

2-Methyl RNA STD Amidites

Amidite