Boc-N-amido-PEG3-sulfonic acid

Product Name: Boc-N-amido-PEG3-sulfonic acid
CAS No.: 1817735-32-2
Chemical Name: Boc-N-amido-PEG3-sulfonic acid
Synonyms: Boc-NH-PEG3-SO3H;Boc-NH-PEG3-sulfonic acid;Boc-N-amido-PEG3-sulfonic acid;5,8,11-Trioxa-2-azatridecanoic acid, 13-sulfo-, 1-(1,1-dimethylethyl) ester
CBNumber: CB93162913
Molecular Formula: C13H27NO8S
Formula Weight: 357.42
MOL File: 1817735-32-2.mol

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Boc-N-amido-PEG3-sulfonic acid Property

Density: 1.219±0.06 g/cm3(Predicted)
pka: 1.34±0.50(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22923
Product name: t-Boc-N-amido-PEG3-sulfonicacid
Purity: 98%
Packaging: 500mg
Price: $750
Updated: 2021/12/16

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Boc-N-amido-PEG3-sulfonic acid Chemical Properties,Usage,Production

Description

t-Boc-N-amido-PEG3-sulfonic acid is a PEG linker containing a t-Boc protected amine group and a sulfonic acid. The t-Boc protecting group can be removed under acidic conditions so that the amine can be further reacted. The sulfonic acid can undergo esterification, halogenation and displacement reactions. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Uses

Boc-NH-PEG3-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Boc-N-amido-PEG3-sulfonic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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1817735-32-2, Boc-N-amido-PEG3-sulfonic acidRelated Search:

t-Boc-N-Amido-PEG4-propargyl 2,2-DIMETHYL-4-OXO-3,8,11,14-TETRAOXA-5-AZAHEXADECAN-16-OIC ACID Boc-NH-PEG7-CH2CH2COOH 22-Amino-5,8,11,14,17,20-hexaoxa-2-azadocosanoic acid 1,1-dimethylethyl ester t-boc-N-amido-PEG5-azide t-Boc-N-amido-PEG5-acid t-Boc-N-Amido-PEG3-propargyl Thiol-dPEG4-t-boc-N-amido t-Boc-N-Amido-PEG4-Azide t-Boc-N-Amido-PEG6-Propargyl t-Boc-N-Amido-PEG4-Ms t-Boc-N-amido-PEG4-(CH2)3CO2H t-Boc-N-amido-PEG5-MS t-Boc-N-amido-PEG5-NHS ester t-Boc-N-Amido-PEG7-propargyl t-Boc-N-Amido-PEG5-propargyl 5,8,11-Trioxa-2-azatridecanoic acid, 13-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester t-Boc-N-Amido-PEG8-propargyl

Boc-N-amido-PEG3-sulfonic acid

Boc-NH-PEG3-SO3H

Boc-NH-PEG3-sulfonic acid

5,8,11-Trioxa-2-azatridecanoic acid, 13-sulfo-, 1-(1,1-dimethylethyl) ester

1817735-32-2

C13H27NO8S