ChemicalBook > CAS DataBase List > 6-Aminonicotinic acid

6-Aminonicotinic acid

Product Name
6-Aminonicotinic acid
CAS No.
3167-49-5
Chemical Name
6-Aminonicotinic acid
Synonyms
3-Pyridinecarboxylic acid, 6-amino-;6- aMinoacid;6-AMinonicotinic a;TIMTEC-BB SBB004186;RARECHEM AL BO 1167;6-Aminonicotinc Acid;6-AMINONICOTINIC ACID;Nicotinic acid, 6-amino-;2-Amino-5-carboxypyridine;6-Aminonicotinic acid 98%
CBNumber
CB9449781
Molecular Formula
C6H6N2O2
Formula Weight
138.12
MOL File
3167-49-5.mol
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6-Aminonicotinic acid Property

Melting point:
>300 °C (lit.)
Boiling point:
253.51°C (rough estimate)
Density 
1.3471 (rough estimate)
refractive index 
1.5100 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
2.86±0.10(Predicted)
form 
Powder
color 
White to beige
Water Solubility 
ca 1.0 g/L (20 ºC)
Merck 
14,456
BRN 
115992
InChI
InChI=1S/C6H6N2O2/c7-5-2-1-4(3-8-5)6(9)10/h1-3H,(H2,7,8)(H,9,10)
InChIKey
ZCIFWRHIEBXBOY-UHFFFAOYSA-N
SMILES
C1=NC(N)=CC=C1C(O)=O
CAS DataBase Reference
3167-49-5(CAS DataBase Reference)
NIST Chemistry Reference
Nicotinic acid, 6-amino-(3167-49-5)
EPA Substance Registry System
3-Pyridinecarboxylic acid, 6-amino- (3167-49-5)
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Safety

Hazard Codes 
Xi,T
Risk Statements 
36/37/38-23/24/25
Safety Statements 
22-24/25-45-36/37/39-26
WGK Germany 
3
TSCA 
T
HazardClass 
IRRITANT
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
216879
Product name
6-Aminopyridine-3-carboxylic acid
Purity
97%
Packaging
5g
Price
$23.45
Updated
2025/07/31
Sigma-Aldrich
Product number
216879
Product name
6-Aminopyridine-3-carboxylic acid
Purity
97%
Packaging
1g
Price
$24.9
Updated
2023/06/20
TCI Chemical
Product number
A1486
Product name
6-Aminonicotinic Acid
Purity
>98.0%(T)
Packaging
1g
Price
$41
Updated
2025/07/31
TCI Chemical
Product number
A1486
Product name
6-Aminonicotinic Acid
Purity
>98.0%(T)
Packaging
5g
Price
$122
Updated
2025/07/31
Usbiological
Product number
A1379-13
Product name
6-Aminonicotinic Acid
Packaging
1g
Price
$355
Updated
2021/12/16
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6-Aminonicotinic acid Chemical Properties,Usage,Production

Chemical Properties

Light yellow Cryst

Uses

6-Aminopyridine-3-carboxylic acid (6-Aminonicotinic acid) was used in the preparation of resin-bound 2-aminoazine.

Uses

Antiproliferative

Application

6-Aminonicotinic acid is an inhibitor of bacterial DNA gyrase and topoisomerase IV. It has been shown to inhibit the growth of a number of bacteria, including E. coli K-12, with potent inhibitory activity against these enzymes. It binds to the active sites on these enzymes and prevents them from working. The detection time for 6-aminonicotinic acid is about 3 hours after exposure. It has been shown to be more potent than other inhibitors of bacterial DNA gyrase and topoisomerase IV such as 2,4-diaminopyrimidine (2,4DAP).

Definition

ChEBI: An aminonicotinic acid in which the amino group is situated at position 6 of the pyridine ring.

General Description

Electrosynthesis of 6-aminopyridine-3-carboxylic acid (6-aminonicotinic acid) by electrochemical reduction of 2-amino-5-bromo and 2-amino-5-chloropyridine in the presence of CO2 at silver electrode has been reported.

Purification Methods

Crystallise the acid from aqueous acetic acid. Dry it in vacuo at 70o. [Beilstein 22 III/IV 6726.]

6-Aminonicotinic acid Preparation Products And Raw materials

Raw materials

2-Amino-5-methylpyridine Ammonium hydroxide Ethanol Acetic anhydride Benzene Hydrochloric acid Potassium permanganate Methanol Sodium hydroxide 4-Dimethylaminopyridine

Preparation Products

5,6-DICHLORONICOTINIC ACID ETHYL ESTER 2-Aminopyridine TERT-BUTYL [5-(HYDROXYMETHYL)PYRIDIN-2-YL)CARBAMATE
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View Lastest Price from 6-Aminonicotinic acid manufacturers

Nanjing Shunxiang Pharmaceutical Technology Co.,Ltd.
Product
6-Aminonicotinic acid 3167-49-5
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1
Release date
2025-09-26
HANGZHOU HAILAN CHEMICAL CO.,LTD.
Product
6-Aminonicotinic acid 3167-49-5
Price
US $0.00/kg
Min. Order
1kg
Purity
99%min
Supply Ability
20tons
Release date
2025-08-25
Henan Aochuang Chemical Co.,Ltd.
Product
6-Aminonicotinic acid 3167-49-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-09

3167-49-5, 6-Aminonicotinic acidRelated Search:

Chromium picolinate 2,5-PYRIDINEDICARBOXYLIC ACID Aminopyrine Acetaminophen Quinolinic acid Glucosamine 2-Aminopyridine Sulfamic acid 3-Aminopyridine EC 2.6.1.2 4-Dimethylaminopyridine 2-chloro-5-cyanopyridine 2-Mercaptonicotinic acid 5,6-Dichloronicotinic acid 2-AMINONICOTINIC ACID,2-Aminonicotinic acid;2-Aminopyridine-3-carboxylic acid,2-Aminonicotinic acid, 98+%,2-Aminonicotinic acid 98% 4-AMINONICOTINIC ACID,4-AMINONICOTINIC ACID, 98.5%,4-Aminonicotinic acid 99% 5-Aminonicotinic acid ,98%,5-AMINONICOTINIC ACID Methyl 6-aminonicotinate

  • 3-Pyridinecarboxylic acid, 6-amino-
  • 6-amino-3-pyridinecarboxylicaci
  • 6-AMINONICOTINIC ACID
  • 6-AMINOPYRIDINE-3-CARBOXYLIC ACID
  • 2-AMINO-5-PYRIDINECARBOXYLIC ACID
  • 2-AMINOPYRIDINE-5-CARBOXYLIC ACID
  • RARECHEM AL BO 1167
  • TIMTEC-BB SBB004186
  • 2-Amino-5-carboxypyridine
  • 6-Amino-3-pyridinecaboxylic acid
  • 6-Aminonicotinic acid;6-Aminopyridine-3-carboxylic acid
  • 6-AMINO-3-PYRIDINE CARBOXLIC ACID
  • 6-Aminonicotinic acid, 98+%
  • 2-Aminopyridine-5-carboxylic acid(6-Aminonicotinic acid)
  • 6-Amino-3-pyridinecarboxylic Acid
  • 6-Aminopyridine-3-carboxylic acid ,98%
  • 6-Aminonicotinic acid 98%
  • 3-Pyridinecarboxylicacid,6-amino-(9CI)
  • 6-Aminonicotinc Acid
  • 2-Aminopyridine-5-carboxylic acid, 6-Aminopyridine-3-carboxylic acid, 6-Amino-3-carboxypyridine
  • 6-aMinopyridine-3-carbo×ylic acid
  • 6-AMinonicotinic a
  • 2-Aminopyridine-5-carboxylic acid, 6-Aminopyridine-3-carboxylic acid, 2-Amino-5-carboxypyridine
  • 6- aMinoacid
  • Nicotinic acid, 6-amino-
  • 2-AMINO-5-CARBOXAMIDE PYRIDINE
  • Nicotinic acid, 6-amino- (8CI)
  • 6-Aminonicotinic Acid &gt
  • 6-Aminonicotinic acid USP/EP/BP
  • 6-Aminonicotinic acid?New
  • 6-Aminonicotinic acid, 10 mM in DMSO
  • 6-Aminopyridine-3-carboxylic acid, 97%
  • 6-Aminopyridin-3-carboxylic acid
  • 3167-49-5
  • 3617-49-5
  • 167-49-5
  • Building Blocks
  • CARBOXYLIC ACID
  • Heterocyclic Building Blocks
  • Pyridines
  • C6
  • Aromatics
  • Chemical Amines
  • Heterocycles
  • Carboxylic Acids
  • AMINOACID
  • Amines
  • blocks
  • Carboxes
  • Pyridines
  • Pyridine
  • pyridine derivative
  • Pyridines, Pyrimidines, Purines and Pteredines
  • pharmacetical
  • Pyridine series
  • Carboxylic Acids
  • Organic acids