Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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Organic reagents

Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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From early AD to mid-19 century, people mainly use the natural organic substance (such as animal and plant extracts) for qualitative analysis or quantitative analysis. From the second half of the 19th century to the 1920s, it had begun to appear of artificially synthetic organic reagent such as using potassium acetate xanthan for test of nickel, copper, and molybdenum; using morin for test of aluminum; using diazo coupling reaction for the detection of Nitrite; using α-β-nitroso naphthol for detection of cobalt; using dimethyglyoxime for nickel test.

After the proposal of the special-effects group in the 1930s and the proposal of theoretical analysis of functional groups theory in 1950s, people had carried out large-scale screen of organic reagents in search of special-effects analysis groups for different ions and had successfully synthesized a lot of agents of practical value (such as copper reagents, new copper agent, cadmium reagents, beryllium reagent, thorium reagents, etc.). Before the 1950s, the complex compound, in analytic chemistry, is mainly used in the aspects of the precipitation reaction of a binary chelate for the qualitative detection, precipitate isolation and gravimetric separation and other aspects. In the early 1950s and 1960, it is mainly in the form of complexometric titration. From the beginning of the late 1960s, the main focus has been moved to the photometric analysis. Meanwhile, it has been also developed of chelate organic solvent extraction.

8-hydroxy quinoline, hydrazones, oximes, hydroxamic acids, polyphenols, 1, 10-phenanthroline, phosphorus-oxygen extractant, β- diketones, triphenylmethane acid dye, xanthene dyes and azo dyes and other agents has all been widely studied and applied. On the other hand, the structural theoretical research (such as electronic effects, spatial effects and substituent effects) of the organic reagent can further facilitate the development of new-type organic reagents such as heterocyclic azo reagent. During this period, it has been also developed of monoazo chromotropic acid-type and disazo chromotropic acid-type reagent. During the mid-1970s, the chelating resin and adsorbents have achieved rapid development. Since the 1980s, Chinese researchers of analytical chemistry have made progress in the field of the synthesis and application of asymmetric disazo chromotropic acid.

Organic chemical reagents have wide application in analytic chemistry and are mainly used in solvents, precipitation agents, complexing agents, indicator, coloring reagent and surface active agent, etc. In order to adapt to a variety of analytical needs, sometimes it is required to purify certain reagents. For example, liquid organic reagent is often purified by distillation while solid substance is often purified through crystallization and sublimation. Substance having a high vapor pressure, namely having low purification boiling point and undergoing no decomposition under boiling temperature commonly applied atmospheric distillation; for less volatile and water-insoluble substance, namely having high purification point or undergoing decomposition under boiling temperature, we can apply vacuum distillation or steam distillation for purification of it.

Distillation is a commonly used method for laboratory purification of organic reagent. Conventional distillation apparatus generally comprises distiller, condenser and receiver, three parts with auxiliary section also containing heater, a thermometer, a wetted tube and cork.

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Structure:
Chemical Name:
BROMOSUCCINIC ACID
CAS:
923-06-8
MF:
C4H5BrO4
Structure:
Chemical Name:
NITRILOTRIACETIC ACID TRISODIUM SALT MONOHYDRATE
CAS:
18662-53-8
MF:
C6H8NNa3O7
Structure:
Chemical Name:
Trimethylolpropane tris(thioglycolate)
CAS:
10193-96-1
MF:
C12H20O6S3
Structure:
Chemical Name:
1,3-PHENYLENE DIISOCYANATE
CAS:
123-61-5
MF:
C8H4N2O2
Structure:
Chemical Name:
2-Methylbenzhydrol
CAS:
5472-13-9
MF:
C14H14O
Structure:
Chemical Name:
4-METHYL-2-PENTENOIC ACID
CAS:
10321-71-8
MF:
C6H10O2
Structure:
Chemical Name:
Cyclopentanone p-Toluenesulfonylhydrazone
CAS:
17529-98-5
MF:
C12H16N2O2S
Structure:
Chemical Name:
O-(4-nitrobenzoyl)hydroxylamine
CAS:
35657-36-4
MF:
C7H6N2O4
Structure:
Chemical Name:
8-isoquinolinyl-boronic acid
CAS:
721401-43-0
MF:
C9H8BNO2
Structure:
Chemical Name:
DIETHYL DIMETHYLMALONATE
CAS:
1619-62-1
MF:
C9H16O4
Structure:
Chemical Name:
CIS-2-METHYLCYCLOHEXANOL
CAS:
7443-70-1
MF:
C7H14O
Structure:
Chemical Name:
4-(ethylaminomethyl)benzonitrile
CAS:
4714-63-0
MF:
C9H10N2
Structure:
Chemical Name:
Guanidine,(2-methyl-5-nitrophenyl)
CAS:
152460-07-6
MF:
C8H10N4O2
Structure:
Chemical Name:
dimesitylammonium pentafluorobenzenesulfonate
CAS:
850629-65-1
MF:
C24H24F5NO3S
Structure:
Chemical Name:
Dodecylguanidine
CAS:
112-65-2
MF:
C13H29N3
Structure:
Chemical Name:
2-METHYL-1-BUTEN-3-YNE
CAS:
78-80-8
MF:
C5H6
Structure:
Chemical Name:
5-Bromo-2-methoxybenzonitrile
CAS:
144649-99-0
MF:
C8H6BrNO
Structure:
Chemical Name:
4-MALEIMIDOBUTYRIC ACID
CAS:
57078-98-5
MF:
C8H9NO4
Structure:
Chemical Name:
2-NONANOL
CAS:
628-99-9
MF:
C9H20O
Structure:
Chemical Name:
CYCLOPROPYL DIPHENYL CARBINOL
CAS:
5785-66-0
MF:
C16H16O
Structure:
Chemical Name:
5-METHYL-3-HEPTANONE
CAS:
541-85-5
MF:
C8H16O
Structure:
Chemical Name:
BORIC ACID TRI-N-DECYL ESTER
CAS:
20236-81-1
MF:
C30H63BO3
Structure:
Chemical Name:
1H,1H-HEPTAFLUOROBUTYL ACRYLATE
CAS:
424-64-6
MF:
C7H5F7O2
Structure:
Chemical Name:
3-BROMOBENZOYLACETONITRILE
CAS:
70591-86-5
MF:
C9H6BrNO
Structure:
Chemical Name:
2,4,4-TRIMETHYLCYCLOPENTANONE
CAS:
4694-12-6
MF:
C8H14O
Structure:
Chemical Name:
4-CHLORO-3-NITROPHENYL ISOCYANATE
CAS:
40397-96-4
MF:
C7H3ClN2O3
Structure:
Chemical Name:
1,2-EPOXY-5-HEXENE
CAS:
10353-53-4
MF:
C6H10O
Structure:
Chemical Name:
(R)-(+)-1,2-EPOXY-9-DECENE
CAS:
137310-67-9
MF:
C10H18O
Structure:
Chemical Name:
TERT-BUTOXYCHLORODIPHENYLSILANE
CAS:
17922-24-6
MF:
C16H19ClOSi
Structure:
Chemical Name:
2-METHYLGLUTARIC ACID
CAS:
18069-17-5
MF:
C6H10O4
Structure:
Chemical Name:
4-OCTANOL
CAS:
589-62-8
MF:
C8H18O
Structure:
Chemical Name:
VINYLCYCLOPENTANE
CAS:
3742-34-5
MF:
C7H12
Structure:
Chemical Name:
PHENYLSELENOCYANATE
CAS:
2179-79-5
MF:
C7H5NSe
Structure:
Chemical Name:
O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE
CAS:
39684-28-1
MF:
C4H12ClNO
Structure:
Chemical Name:
2-(4-HYDROXYPHENOXY)PROPIONIC ACID
CAS:
67648-61-7
MF:
C9H10O4
Structure:
Chemical Name:
N-(3-HYDROXYPROPYL)PHTHALIMIDE
CAS:
883-44-3
MF:
C11H11NO3
Structure:
Chemical Name:
TETRA-N-BUTYLAMMONIUM TRIIODIDE
CAS:
13311-45-0
MF:
C16H36I3N
Structure:
Chemical Name:
(2-METHYLPHENOXY)ACETIC ACID
CAS:
1878-49-5
MF:
C9H10O3
Structure:
Chemical Name:
2,2'-OXYDIANILINE
CAS:
24878-25-9
MF:
C12H12N2O
Structure:
Chemical Name:
BENZYLDIMETHYLPHENYLAMMONIUM CHLORIDE
CAS:
3204-68-0
MF:
C15H18ClN
Structure:
Chemical Name:
4-(TRIFLUOROMETHYLTHIO)BROMOBENZENE
CAS:
333-47-1
MF:
C7H4BrF3S
Structure:
Chemical Name:
2-NAPHTHYL LAURATE
CAS:
6343-73-3
MF:
C22H30O2
Structure:
Chemical Name:
Flopropione
CAS:
2295-58-1
MF:
C9H10O4
Structure:
Chemical Name:
Mesaconic acid
CAS:
498-24-8
MF:
C5H6O4
Structure:
Chemical Name:
BORIC ACID TRI-N-TETRADECYL ESTER
CAS:
23162-15-4
MF:
C42H87BO3
Structure:
Chemical Name:
2-CHLORO-5-(TRIFLUOROMETHYL)PHENYL ISOCYANATE
CAS:
50528-86-4
MF:
C8H3ClF3NO
Structure:
Chemical Name:
3-Nitroanisole
CAS:
555-03-3
MF:
C7H7NO3
Structure:
Chemical Name:
1,1-Dibromoethane
CAS:
557-91-5
MF:
C2H4Br2
Structure:
Chemical Name:
O-Benzylhydroxylamine
CAS:
622-33-3
MF:
C7H9NO
Structure:
Chemical Name:
2-(4-Chlorosulphonylphenyl)ethyl trichlorosilanein methylene chloride
CAS:
79793-00-3
MF:
C8H8Cl4O2SSi
Structure:
Chemical Name:
N-Iodosaccharin
CAS:
86340-94-5
MF:
C7H4INO3S
Structure:
Chemical Name:
(5-Fluoro-2-methyl-1H-inden-3-yl)acetic acid
CAS:
32004-66-3
MF:
C12H11FO2
Structure:
Chemical Name:
1-(4-Bromophenyl)-naphthlene
CAS:
204530-94-9
MF:
C16H11Br
Structure:
Chemical Name:
CIS-EPOXYSUCCINIC ACID
CAS:
16533-72-5
MF:
C4H4O5
Structure:
Chemical Name:
2-ACETYL-1-TETRALONE
CAS:
17216-08-9
MF:
C12H12O2
Structure:
Chemical Name:
4-CHLOROMETHYLPHENYLBORONIC ACID
CAS:
164413-77-8
MF:
C7H8BClO2
Structure:
Chemical Name:
3-Butoxyphenol
CAS:
18979-72-1
MF:
C10H14O2
Structure:
Chemical Name:
N-TETRACONTANE
CAS:
4181-95-7
MF:
C40H82
Structure:
Chemical Name:
P-TOLUIC HYDRAZIDE
CAS:
3619-22-5
MF:
C8H10N2O
Structure:
Chemical Name:
2,4-DIMETHYLTHIOSEMICARBAZIDE
CAS:
6621-75-6
MF:
C3H9N3S
Structure:
Chemical Name:
2-Chlorobenzaldehyde oxime
CAS:
3717-28-0
MF:
C7H6ClNO
Structure:
Chemical Name:
1-(4-CHLOROPHENYL)-3-PHENYL-2-THIOUREA
CAS:
7392-67-8
MF:
C13H11ClN2S
Structure:
Chemical Name:
LAS-C10
CAS:
1322-98-1
MF:
C16H25NaO3S
Structure:
Chemical Name:
(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE
CAS:
102191-92-4
MF:
C8H18O2Si
Structure:
Chemical Name:
TRIS(ACETONITRILE)CYCLOPENTADIENYLRUTHENIUM(II) HEXAFLUOROPHOSPHATE
CAS:
80049-61-2
MF:
C11H14F6N3PRu5*
Structure:
Chemical Name:
BENZO[1,3]DIOXOLE-5-SULFONYL CHLORIDE
CAS:
115010-10-1
MF:
C7H5ClO4S
Structure:
Chemical Name:
2-VINYLPHENYLBORONIC ACID
CAS:
15016-42-9
MF:
C8H9BO2
Structure:
Chemical Name:
2-BUTENE
CAS:
624-64-6
MF:
C4H8
Structure:
Chemical Name:
TETRAETHYLAMMONIUM P-TOLUENESULFONATE
CAS:
733-44-8
MF:
C15H27NO3S
Structure:
Chemical Name:
1-PENTYN-3-OL
CAS:
4187-86-4
MF:
C5H8O
Structure:
Chemical Name:
NITRON
CAS:
2218-94-2
MF:
C20H16N4
Structure:
Chemical Name:
3-NONANONE
CAS:
925-78-0
MF:
C9H18O
Structure:
Chemical Name:
N-Acetyl-1-aminonaphthalene
CAS:
575-36-0
MF:
C12H11NO
Structure:
Chemical Name:
4-METHOXY-1-NAPHTHOL
CAS:
84-85-5
MF:
C11H10O2
Structure:
Chemical Name:
3-Methylcrotonoyl chloride
CAS:
3350-78-5
MF:
C5H7ClO
Structure:
Chemical Name:
1,5-DIBROMOANTHRAQUINONE
CAS:
602-77-7
MF:
C14H6Br2O2
Chemical Name:
POLY-BETA-CYCLODEXTRIN
Structure:
Chemical Name:
3-TERT-BUTYLADIPIC ACID
CAS:
10347-88-3
MF:
C10H18O4
Structure:
Chemical Name:
TRANS-3-HEPTENE
CAS:
592-78-9
MF:
C7H14
Structure:
Chemical Name:
9-Fluorenone-2-carboxylic acid
CAS:
784-50-9
MF:
C14H8O3
Structure:
Chemical Name:
N-Methylolchloroacetamide
CAS:
2832-19-1
MF:
C3H6ClNO2
Structure:
Chemical Name:
Ethyl 1,3-dithiane-2-carboxylate
CAS:
20462-00-4
MF:
C7H12O2S2
Structure:
Chemical Name:
BISPHENOL A BIS(CHLOROFORMATE)
CAS:
2024-88-6
MF:
C17H14Cl2O4
Structure:
Chemical Name:
2,4,4'-TRIHYDROXYBENZOPHENONE
CAS:
1470-79-7
MF:
C13H10O4
Structure:
Chemical Name:
2-METHYLCYCLOPROPANECARBOXYLIC ACID
CAS:
29555-02-0
MF:
C5H8O2
Structure:
Chemical Name:
L-Glutamic acid γ-(4-nitroanilide)
CAS:
7300-59-6
MF:
C11H13N3O5
Structure:
Chemical Name:
Methyl 4-iodosalicylate
CAS:
18179-39-0
MF:
C8H7IO3
Structure:
Chemical Name:
TRANS-4-(TRIFLUOROMETHYL)CYCLOHEXANECARBOXYLIC ACID
CAS:
133261-33-3
MF:
C8H11F3O2
Structure:
Chemical Name:
METHYL 3-(TRIMETHYLSILYLOXY)CROTONATE, MIXTURE OF CIS AND TRANS, 90
CAS:
26767-00-0
MF:
C8H16O3Si
Structure:
Chemical Name:
2-(4-BROMOBUTYL)-1 3 2-BENZODIOXABOROLE&
CAS:
142172-51-8
MF:
C10H12BBrO2
Structure:
Chemical Name:
POTASSIUM GUAIACOLSULFONATE
CAS:
7134-11-4
MF:
C7H8O5S
Structure:
Chemical Name:
SULFONAL
CAS:
115-24-2
MF:
C7H16O4S2
Structure:
Chemical Name:
9-FLUORENONE-1-CARBOXYLIC ACID
CAS:
1573-92-8
MF:
C14H8O3
Structure:
Chemical Name:
DCU
CAS:
13698-16-3
MF:
C3H5Cl2NO2
Structure:
Chemical Name:
5-CYANO-1-PENTYNE
CAS:
14918-21-9
MF:
C6H7N
Structure:
Chemical Name:
2-Bromo-2′-hydroxyacetophenone
CAS:
2491-36-3
MF:
C8H7BrO2
Structure:
Chemical Name:
1,6-DIMETHOXYHEXANE
CAS:
13179-98-1
MF:
C8H18O2
Structure:
Chemical Name:
2,5-Dimethylbenzaldehyde
CAS:
5779-94-2
MF:
C9H10O
Structure:
Chemical Name:
4,4'-BIS(N-HEXYLOXY)AZOXYBENZENE
CAS:
2587-42-0
MF:
C24H34N2O3
Structure:
Chemical Name:
2-CHLORO-4-NITROPHENYL ISOTHIOCYANATE
CAS:
23165-64-2
MF:
C7H3ClN2O2S