Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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Organic reagents

Esters Aromatic acids fatty acid Fatty alcohols Boric acid Cyanide / nitrile Aromatic ketones Aromatic aldehydes Halogenated aliphatic hydrocarbons aliphatic ketones Amide Ethers Aromatics Aromatic alcohol Phosphine ligand Phenols Thiol / thiol Silane Acyl halide Sulfonates / Sulfinates salts Cyanate ester / isocyanate Nitro compounds Imide Olefin (cyclic and acyclic) The polycyclic compound Hydrazine Amine salt (ammonium salt) Aliphatic aldehydes Bicyclic compound Oxime Tricyclic compound Alkanes Sulfonyl halide Phosphonate / phosphonate Phosphorus halide Alkyne Carboxylic anhydride Urea Phosphorus-containing compound Siloxane Azo, diazo compound Ionic Liquids Thiocyanate / isothiocyanate Borate Sulfonates / Sulfinates Selenium compounds Guanidine salt Borane Thiourea Thiolate tetrafluoroborate Thiol ester Polycyclic compound Crown ether Sulfone, sulfoxide compound Hydrazone Imide, amidine Polyamines Tosylate Epoxide Azide Hydroxylamine Cyclodextrin
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From early AD to mid-19 century, people mainly use the natural organic substance (such as animal and plant extracts) for qualitative analysis or quantitative analysis. From the second half of the 19th century to the 1920s, it had begun to appear of artificially synthetic organic reagent such as using potassium acetate xanthan for test of nickel, copper, and molybdenum; using morin for test of aluminum; using diazo coupling reaction for the detection of Nitrite; using α-β-nitroso naphthol for detection of cobalt; using dimethyglyoxime for nickel test.

After the proposal of the special-effects group in the 1930s and the proposal of theoretical analysis of functional groups theory in 1950s, people had carried out large-scale screen of organic reagents in search of special-effects analysis groups for different ions and had successfully synthesized a lot of agents of practical value (such as copper reagents, new copper agent, cadmium reagents, beryllium reagent, thorium reagents, etc.). Before the 1950s, the complex compound, in analytic chemistry, is mainly used in the aspects of the precipitation reaction of a binary chelate for the qualitative detection, precipitate isolation and gravimetric separation and other aspects. In the early 1950s and 1960, it is mainly in the form of complexometric titration. From the beginning of the late 1960s, the main focus has been moved to the photometric analysis. Meanwhile, it has been also developed of chelate organic solvent extraction.

8-hydroxy quinoline, hydrazones, oximes, hydroxamic acids, polyphenols, 1, 10-phenanthroline, phosphorus-oxygen extractant, β- diketones, triphenylmethane acid dye, xanthene dyes and azo dyes and other agents has all been widely studied and applied. On the other hand, the structural theoretical research (such as electronic effects, spatial effects and substituent effects) of the organic reagent can further facilitate the development of new-type organic reagents such as heterocyclic azo reagent. During this period, it has been also developed of monoazo chromotropic acid-type and disazo chromotropic acid-type reagent. During the mid-1970s, the chelating resin and adsorbents have achieved rapid development. Since the 1980s, Chinese researchers of analytical chemistry have made progress in the field of the synthesis and application of asymmetric disazo chromotropic acid.

Organic chemical reagents have wide application in analytic chemistry and are mainly used in solvents, precipitation agents, complexing agents, indicator, coloring reagent and surface active agent, etc. In order to adapt to a variety of analytical needs, sometimes it is required to purify certain reagents. For example, liquid organic reagent is often purified by distillation while solid substance is often purified through crystallization and sublimation. Substance having a high vapor pressure, namely having low purification boiling point and undergoing no decomposition under boiling temperature commonly applied atmospheric distillation; for less volatile and water-insoluble substance, namely having high purification point or undergoing decomposition under boiling temperature, we can apply vacuum distillation or steam distillation for purification of it.

Distillation is a commonly used method for laboratory purification of organic reagent. Conventional distillation apparatus generally comprises distiller, condenser and receiver, three parts with auxiliary section also containing heater, a thermometer, a wetted tube and cork.

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Structure:
Chemical Name:
Bromonitromethane
CAS:
563-70-2
MF:
CH2BrNO2
Structure:
Chemical Name:
(4-NITROBENZYL)TRIPHENYLPHOSPHONIUM BROMIDE
CAS:
2767-70-6
MF:
C25H21BrNO2P
Structure:
Chemical Name:
NAPHTHOL YELLOW S
CAS:
846-70-8
MF:
C10H4N2Na2O8S
Structure:
Chemical Name:
3-METHYLENE-2-NORBORNANONE
CAS:
5597-27-3
MF:
C8H10O
Structure:
Chemical Name:
3-CHLORO-2-METHYLBENZONITRILE
CAS:
54454-12-5
MF:
C8H6ClN
Structure:
Chemical Name:
2,5-Dibromohexane
CAS:
24774-58-1
MF:
C6H12Br2
Structure:
Chemical Name:
2-(4-METHOXYPHENYL)HYDRAZINESULFONIC ACID SODIUM SALT MONOHYDRATE
CAS:
5446-07-1
MF:
C7H9N2NaO4S
Structure:
Chemical Name:
DIMETHYL CIS-1,2-CYCLOPROPANEDICARBOXYLATE
CAS:
826-34-6
MF:
C7H10O4
Structure:
Chemical Name:
2,6-DIMETHOXYTOLUENE
CAS:
5673-07-4
MF:
C9H12O2
Structure:
Chemical Name:
4-N-HEXYLOXYBENZALDEHYDE
CAS:
5736-94-7
MF:
C13H18O2
Structure:
Chemical Name:
2,4-HEXADIYNE-1,6-DIOL
CAS:
3031-68-3
MF:
C6H6O2
Structure:
Chemical Name:
4-CARBOXYBENZENESULFONYL AZIDE
CAS:
17202-49-2
MF:
C7H5N3O4S
Structure:
Chemical Name:
2-BROMOHEXANE
CAS:
3377-86-4
MF:
C6H13Br
Structure:
Chemical Name:
N-TRIDECYLBENZENE
CAS:
123-02-4
MF:
C19H32
Structure:
Chemical Name:
4-NITROPHENYL TRIFLUOROMETHANESULFONATE
CAS:
17763-80-3
MF:
C7H4F3NO5S
Structure:
Chemical Name:
2-CHLORO-6-METHYLBENZALDEHYDE
CAS:
1194-64-5
MF:
C8H7ClO
Structure:
Chemical Name:
6-(1,4-DIAZEPAN-1-YL)NICOTINONITRILE
CAS:
683274-59-1
MF:
C11H14N4
Structure:
Chemical Name:
4-Amino-3,5-diiodobenzoic acid
CAS:
2122-61-4
MF:
C7H5I2NO2
Structure:
Chemical Name:
BIS(4-METHOXYPHENYL) DISULPHIDE
CAS:
5335-87-5
MF:
C14H14O2S2
Structure:
Chemical Name:
5,10,15,20-TETRAKIS(4-HYDROXYPHENYL)-21H,23H-PORPHINE
CAS:
51094-17-8
MF:
C44H30N4O4
Structure:
Chemical Name:
4-ETHYLPHENYL ISOCYANATE
CAS:
23138-50-3
MF:
C9H9NO
Structure:
Chemical Name:
CYCLOHEXYLACETYLENE
CAS:
931-48-6
MF:
C8H12
Structure:
Chemical Name:
4,5-Dimethoxy-2-(trimethylsilyl)phenyl Trifluoromethanesulfonate
CAS:
866252-52-0
MF:
C12H17F3O5SSi
Structure:
Chemical Name:
BETA-CYCLOCITRAL
CAS:
432-25-7
MF:
C10H16O
Structure:
Chemical Name:
BORON TRIFLUORIDE, N-PROPANOL REAGENT 15
CAS:
762-48-1
MF:
C3H7BF3O
Structure:
Chemical Name:
3-HEXADECANONE
CAS:
18787-64-9
MF:
C16H32O
Structure:
Chemical Name:
1-HEPTANESULFONIC ACID SODIUM SALT MONOHYDRATE
CAS:
207300-90-1
MF:
C7H17NaO4S
Structure:
Chemical Name:
DIETHYL (CHLOROMETHYL)PHOSPHONATE
CAS:
3167-63-3
MF:
C5H12ClO3P
Structure:
Chemical Name:
6-O-(TRIISOPROPYLSILYL)-D-GLUCAL
CAS:
137915-37-8
MF:
C15H30O4Si
Structure:
Chemical Name:
1H,1H,7H-DODECAFLUORO-1-HEPTANOL
CAS:
335-99-9
MF:
C7H4F12O
Structure:
Chemical Name:
DL-2-Methylbutyryl chloride
CAS:
57526-28-0
MF:
C5H9ClO
Structure:
Chemical Name:
PHENOXATHIIN-4-BORONIC ACID
CAS:
100124-07-0
MF:
C12H9BO3S
Structure:
Chemical Name:
GLYCIDYL ISOPROPYL ETHER
CAS:
4016-14-2
MF:
C6H12O2
Structure:
Chemical Name:
TETRAMETHYLAMMONIUM HEXAFLUOROPHOSPHATE
CAS:
558-32-7
MF:
C4H12F6NP
Structure:
Chemical Name:
CROTONALDEHYDE (DNPH DERIVATIVE)
CAS:
1527-96-4
MF:
C10H10N4O4
Structure:
Chemical Name:
3,5-DICHLORO-2-HYDROXYBENZENESULFONYL CHLORIDE
CAS:
23378-88-3
MF:
C6H3Cl3O3S
Structure:
Chemical Name:
2,3-DIMETHYL-6-NITROANILINE
CAS:
59146-96-2
MF:
C8H10N2O2
Structure:
Chemical Name:
(R)-(+)-TolBINAP
CAS:
99646-28-3
MF:
C48H40P2
Structure:
Chemical Name:
3-FLUORO-4-HYDROXYPHENYLACETIC ACID
CAS:
458-09-3
MF:
C8H7FO3
Structure:
Chemical Name:
NONENYLSUCCINIC ANHYDRIDE
CAS:
28928-97-4
MF:
C13H20O3
Structure:
Chemical Name:
SODIUM XYLENESULFONATE
CAS:
30587-85-0
MF:
C8H9NaO3S
Structure:
Chemical Name:
METHOXY-BIS(DIMETHYLAMINO)METHANE
CAS:
1186-70-5
MF:
C6H16N2O
Structure:
Chemical Name:
1-CYCLOPENTENYLACETONITRILE
CAS:
22734-04-9
MF:
C7H9N
Structure:
Chemical Name:
DIBROMOACETONITRILE
CAS:
3252-43-5
MF:
C2HBr2N
Structure:
Chemical Name:
1-Propanesulfonic acid
CAS:
5284-66-2
MF:
C3H8O3S
Structure:
Chemical Name:
(-)-B-METHOXYDIISOPINOCAMPHEYLBORANE
CAS:
99438-28-5
MF:
C21H37BO
Structure:
Chemical Name:
ARACHIDIC ANHYDRIDE
CAS:
55726-22-2
MF:
C40H78O3
Structure:
Chemical Name:
4-(Trifluoromethylthio)benzyl alcohol
CAS:
56456-52-1
MF:
C8H7F3OS
Structure:
Chemical Name:
3-(N-Styrylmethyl-2-aminoethylamino)-propyltrimethoxysilane hydrochloride
CAS:
34937-00-3
MF:
C17H31ClN2O3Si
Structure:
Chemical Name:
Sodium 1-hexanesulfonate monohydrate
CAS:
207300-91-2
MF:
C6H17NaO4S
Structure:
Chemical Name:
S-ETHYL TRIFLUOROTHIOACETATE
CAS:
383-64-2
MF:
C4H5F3OS
Structure:
Chemical Name:
DIPHENYLENEIODONIUM CHLORIDE
CAS:
4673-26-1
MF:
C12H8ClI
Structure:
Chemical Name:
Diethyl amino methyl triethoxy silane
CAS:
15180-47-9
MF:
C11H27NO3Si
Structure:
Chemical Name:
VINYL BENZOATE
CAS:
769-78-8
MF:
C9H8O2
Structure:
Chemical Name:
1,5-DIMETHYLNAPHTHALENE
CAS:
571-61-9
MF:
C12H12
Structure:
Chemical Name:
5-CHLORO-2-METHYLPHENYL ISOTHIOCYANATE
CAS:
19241-36-2
MF:
C8H6ClNS
Structure:
Chemical Name:
3,3-DIMETHYL-1-(2-CARBOXYPHENYL)TRIAZENE
CAS:
20119-28-2
MF:
C9H11N3O2
Structure:
Chemical Name:
(2S,3S)-(-)-BIS(DIPHENYLPHOSPHINO)BUTANE
CAS:
64896-28-2
MF:
C28H28P2
Structure:
Chemical Name:
1-(3,4-DIMETHOXYBENZYL)-6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE
MF:
C20H26ClNO4
Structure:
Chemical Name:
VINYL CINNAMATE
CAS:
3098-92-8
MF:
C11H10O2
Structure:
Chemical Name:
ETHYL TRANS-4-BROMOCINNAMATE
CAS:
24393-53-1
MF:
C11H11BrO2
Structure:
Chemical Name:
TRIALLYL 1,3,5-BENZENETRICARBOXYLATE
CAS:
17832-16-5
MF:
C18H18O6
Structure:
Chemical Name:
3-FLUORO-5-METHYLBENZENEBORONIC ACID
CAS:
850593-06-5
MF:
C7H8BFO2
Structure:
Chemical Name:
4-METHYL-6-TRIFLUOROMETHYL-PYRIMIDINE-2-THIOL
MF:
C6H5F3N2S
Structure:
Chemical Name:
1-Bromoethyl acetate
CAS:
40258-78-4
MF:
C4H7BrO2
Structure:
Chemical Name:
ETHIOFENCARB-SULFONE
CAS:
53380-23-7
MF:
C11H15NO4S
Structure:
Chemical Name:
3,4,5-TRIMETHOXYPHENYL ISOTHIOCYANATE
CAS:
35967-24-9
MF:
C10H11NO3S
Structure:
Chemical Name:
PALMITIC ACID VINYL ESTER
CAS:
693-38-9
MF:
C18H34O2
Structure:
Chemical Name:
2-ETHOXYBENZYL ALCOHOL
CAS:
71672-75-8
MF:
C9H12O2
Structure:
Chemical Name:
4-(2-Hydroxyethoxy)benzaldehyde
CAS:
22042-73-5
MF:
C9H10O3
Structure:
Chemical Name:
tert-Butyl(triphenylphosphoranylidene)acetate
CAS:
35000-38-5
MF:
C24H25O2P
Structure:
Chemical Name:
4-N-BUTYLPHENYL ISOCYANATE
CAS:
69342-47-8
MF:
C11H13NO
Structure:
Chemical Name:
Trioctyl borate
CAS:
2467-12-1
MF:
C24H51BO3
Structure:
Chemical Name:
5-(BICYCLOHEPTENYL)TRIETHOXYSILANE
CAS:
18401-43-9
MF:
C13H24O3Si
Structure:
Chemical Name:
TETRAFLUOROISOPHTHALIC ACID
CAS:
1551-39-9
MF:
C8H2F4O4
Structure:
Chemical Name:
2-Chlorothiobenzamide
CAS:
15717-17-6
MF:
C7H6ClNS
Structure:
Chemical Name:
1,4-DIMETHYLCYCLOHEXANE
CAS:
589-90-2
MF:
C8H16
Structure:
Chemical Name:
Perchloromethylmercaptan
CAS:
594-42-3
MF:
CCl4S
Structure:
Chemical Name:
1-(4-BIPHENYLYL)ETHANOL
CAS:
3562-73-0
MF:
C14H14O
Structure:
Chemical Name:
4,5-DICHLOROPHTHALIC ACID
CAS:
56962-08-4
MF:
C8H4Cl2O4
Structure:
Chemical Name:
2,7-Naphthalenedicarboxylic acid
CAS:
2089-89-6
MF:
C12H8O4
Structure:
Chemical Name:
CYCLOPENTYLACETYLENE
CAS:
930-51-8
MF:
C7H10
Structure:
Chemical Name:
3-Pentadecylphenol
CAS:
501-24-6
MF:
C21H36O
Structure:
Chemical Name:
TRANS-2-(4-CHLOROPHENYL)VINYLBORONIC ACID
CAS:
154230-29-2
MF:
C8H8BClO2
Structure:
Chemical Name:
4-NITRO-P-TERPHENYL
CAS:
10355-53-0
MF:
C18H13NO2
Structure:
Chemical Name:
O-Mesitylenesulfonylhydroxylamine
CAS:
36016-40-7
MF:
C9H13NO3S
Structure:
Chemical Name:
PHENYLTHIOACETONITRILE
CAS:
5219-61-4
MF:
C8H7NS
Structure:
Chemical Name:
1,4-DIMETHYLNAPHTHALENE
CAS:
571-58-4
MF:
C12H12
Structure:
Chemical Name:
2,5-DIMETHYLHEXANE
CAS:
592-13-2
MF:
C8H18
Structure:
Chemical Name:
4-(CHLOROMETHYL)PHENYL ISOCYANATE
CAS:
29173-65-7
MF:
C8H6ClNO
Structure:
Chemical Name:
1-AMINOANTHRACENE
CAS:
610-49-1
MF:
C14H11N
Structure:
Chemical Name:
1-Butyl-1-methylpiperidinium Bromide
CAS:
94280-72-5
MF:
C10H22BrN
Structure:
Chemical Name:
BISPHENOL A DIACETATE
CAS:
10192-62-8
MF:
C19H20O4
Structure:
Chemical Name:
9-ETHYNYL-9-FLUORENOL
CAS:
13461-74-0
MF:
C15H10O
Structure:
Chemical Name:
Didodecylamine
CAS:
3007-31-6
MF:
C24H51N
Structure:
Chemical Name:
1-Cyano-1-cyclopropanecarboxylic acid
CAS:
6914-79-0
MF:
C5H5NO2
Structure:
Chemical Name:
3-CYANOPHENYL ISOTHIOCYANATE
CAS:
3125-78-8
MF:
C8H4N2S
Structure:
Chemical Name:
2-(2-DODECYLOXYETHOXY)ETHANOL
CAS:
3055-93-4
MF:
C16H34O3
Structure:
Chemical Name:
2-BUTENE-1,4-DIOL
CAS:
821-11-4
MF:
C4H8O2
Structure:
Chemical Name:
4-Nitrophenyl formate
CAS:
1865-01-6
MF:
C7H5NO4