Nodakenin
Nodakenin Basic information
- Product Name:
- Nodakenin
- Synonyms:
-
- (R)-2-[1-(β-D-Glucopyranosyloxy)-1-methylethyl]-2,3-dihydro-7H-furo[3,2-g][1]benzopyran-7-one
- NODAKENIN
- (2R)-2-[2-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropan-2-yl]-2,3-dihydrofuro[3,2-g]chromen-7-one
- 2-(7-Oxo-2,3-dihydro-7H-furo[3,2-g]chromen-3-yl)-2-propanyl β-D-glucopyranoside
- Nodakenin, 98%, from Angelica decursiva (Miq.) Franch. & Sav.
- AliNodakenin
- 7H-Furo[3,2-g][1]benzopyran-7-one, 2-[1-(β-D-glucopyranosyloxy)-1-methylethyl]-2,3-dihydro-, (2R)-
- Nodakenin USP/EP/BP
- CAS:
- 495-31-8
- MF:
- C20H24O9
- MW:
- 408.4
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 495-31-8.mol
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Nodakenin Chemical Properties
- Melting point:
- melting at 216°
- alpha
- D30 +56.6°
- Boiling point:
- 657.1±55.0 °C(Predicted)
- Density
- 1.51±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- Chloroform (Slightly, Sonicated), DMSO (Slightly)
- form
- Solid
- pka
- 12.90±0.70(Predicted)
- color
- Off-White to Pale Beige
- InChIKey
- HXCGUCZXPFBNRD-VPVUCYOBNA-N
- SMILES
- C([C@@H]1OC2=CC3OC(=O)C=CC=3C=C2C1)(C)(C)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O |&1:1,18,19,20,22,24,r|
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Safety Information
- Safety Statements
- 24/25
- HS Code
- 29389090
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Nodakenin Usage And Synthesis
Chemical Properties
White crystalline powder, soluble in methanol, derived from the plant Peucedanum purpurogenum and Angelica radix.
Uses
Nodakenin is a compound used for inhibiting influenza virus including Nodakenin and/or Nodakenetin.
Definition
ChEBI: Nodakenin is a furanocoumarin.
in vivo
Nodakenin (10 mg/kg, p.o.) reverses scopolamine-induced cognitive impairments in the passive avoidance test and the Y-maze test[1].
Nodakenin (10 mg/kg, p.o.) reduces escape latency during training in the Morris water maze test[1].
| Animal Model: | Male ICR mice |
| Dosage: | 2.5, 5, 10 and 20 mg/kg |
| Administration: | p.o, single dose |
| Result: | Reversed in step-through latency induced by scopolamine. |
IC 50
AChE
NodakeninSupplier
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