CROTON OIL Chemical Properties

Density 

0.94 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.477

Flash point:

74 °C

form 

Oil

color 

Pale Yellow to Brown

Water Solubility 

Soluble in alcohol, chloroform, ether, and petroleum ether. Insoluble in water.

Merck 

14,2598

CAS DataBase Reference

8001-28-3

EPA Substance Registry System

Croton oil (8001-28-3)

Safety Information

Safety Statements 

23-24/25

RIDADR 

2810

WGK Germany 

3

RTECS 

GQ6300000

TSCA 

Yes

HS Code 

3301.29.5150

HazardClass 

6.1(b)

PackingGroup 

III

MSDS

• Language:English Provider:SigmaAldrich

CROTON OIL Usage And Synthesis

Chemical Properties

Brownish-yellow liquid. Soluble in ether, chloroform, and fixed or volatile oils; slightly soluble in alcohol.

Uses

Croton Oil is a natural source of phorbol, phorbol esters and glycerides of saturated fatty acids. Croton seeds are sometimes applied directly to the skin for muscle and joint pain. The main use for croton oil today is as an active ingredient in phenol-based facial peels. Dermatologists, plastic surgeons and other practitioners can vary the amount of croton oil in the peel to customize the treatment for a particular patient or skin area, such as on the neck or around the eyes. In Malaysia, people use croton oil in lamps and in soap.

Uses

Croton oil has been used to induce acute skin inflammation.

Uses

Medicine (counterirritant, cathartic).

Definition

Extractives and their physically modified derivatives. Croton tiglium, Euphorbiaceae.

General Description

Colorless liquid with an unpleasant odor. Less dense than water and insoluble in water. Hence floats on water. A mixture of esters (the glycerides of stearic, palmitic myristic, lauric and oleic acids) and croton resin. Toxic and a strong skin irritant.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

OILS, MISCELLANEOUS: CROTON react with acids to liberate heat. Heat is also generated by interaction with caustic solutions. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Flammable hydrogen is generated by mixing with alkali metals and hydrides.

Hazard

Strong skin irritant, ingestion of small amounts may be fatal.

Fire Hazard

CROTON OIL is probably combustible.

CROTON OIL(8001-28-3)Related Product Information

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