Basic information Safety Supplier Related

PROTAC K-Ras Degrader-1

Basic information Safety Supplier Related

PROTAC K-Ras Degrader-1 Basic information

Product Name:
PROTAC K-Ras Degrader-1
Synonyms:
  • PROTAC K-Ras Degrader-1
  • K-Ras Degrader-1
  • 2-Piperazineacetonitrile, 4-[2-[[(2S,4R)-4-[2-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]-1-methyl-2-pyrrolidinyl]methoxy]-5,6,7,8-tetrahydro-7-(1-naphthalenyl)pyrido[3,4-d]pyrimidin-4-yl]-1-(1-oxo-2-propen-1-yl)-, (2S)-
CAS:
2378258-52-5
MF:
C53H62N10O10
MW:
999.14
Mol File:
2378258-52-5.mol
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PROTAC K-Ras Degrader-1 Chemical Properties

Density 
1.40±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 33.33 mg/mL (33.36 mM)
pka
10.74±0.40(Predicted)
form 
Solid
color 
Light yellow to yellow
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PROTAC K-Ras Degrader-1 Usage And Synthesis

Description

PROTAC K-Ras Degrader-1 (Compound 518) is potent K-Ras degrader based PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells[1].

References

[1]. CREW, Andrew P., et al. MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. WO2019195609A2.

PROTAC K-Ras Degrader-1Supplier

Jilin Province Woda Biotechnology Co., Ltd.
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13504435624
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1927928688@qq.com
TargetMol Chemicals Inc.
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+1-781-999-5354 +1-00000000000
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marketing@targetmol.com
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
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sales@chemegen.com
cjbscvictory
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13348960310 13348960310
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3003867561@qq.com
Changzhou Bojia Biomedical Technology Co., Ltd.
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2122619822
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czbjpharma@126.com