PROTAC CRBN Degrader-1 CAS#: 2358775-70-7

PROTAC CRBN Degrader-1 Basic information

Product Name:

PROTAC CRBN Degrader-1

Synonyms:

PROTAC CRBN Degrader-1
CRBN PROTAC?14a
N1-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)-N20-((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-3,9,12,18-tetraoxaicosane-1,20-diamide
N'-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethyl)-N-[(2S)-1-[(2S,4R)-4-hydroxy-2-({[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}carbamoyl)pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]-3,9,12,18-tetraoxaicosanediamide

CAS:

2358775-70-7

MF:

C53H72N8O13S

MW:

1061.25

Mol File:

Mol File

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PROTAC CRBN Degrader-1 Chemical Properties

Boiling point:: 1241.2±65.0 °C(Predicted)
Density: 1.294±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 200 mg/mL (188.46 mM)
form: Solid
pka: 10.74±0.40(Predicted)
color: Light yellow to yellow

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PROTAC CRBN Degrader-1 Usage And Synthesis

Description

CRBN PROTAC? 14a is a cereblon degrader. It comprises a ligand for Von Hippel Lindau (VHL) protein joined by a linker to a cereblon targeting ligand. It preferentially degrades cereblon, and induces rapid and profound cereblon degradation.

storage

Store at -20°C

PROTAC CRBN Degrader-1Supplier

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Email: 3003855609@qq.com

Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Email: sales@chemegen.com

Guangzhou Younan Technology Co., Ltd

Tel: 020-82000279 18988968278
Email: sales@ubiochem.com

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