PROTAC IRAK4 degrader-1 CAS#: 2360533-90-8

PROTAC IRAK4 degrader-1 Basic information

Product Name:

PROTAC IRAK4 degrader-1

Synonyms:

PROTAC IRAK4 degrader-1
2-{2-[(cyclopropylmethyl)amino]pyridin-4-yl}-N-{1-[4-({3-[4-({[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}methyl)-1H-imidazol-1-yl]propyl}carbamoyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-4-yl}-1,3-oxazole-4-carboxamide

CAS:

2360533-90-8

MF:

C44H39F3N12O7

MW:

904.85

Mol File:

Mol File

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PROTAC IRAK4 degrader-1 Chemical Properties

Density: 1.61±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
pka: 10.74±0.40(Predicted)
form: Solid
color: White to yellow

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PROTAC IRAK4 degrader-1 Usage And Synthesis

Biological Activity

PROTAC IRAK4 degrader-1 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1 Compound I-210, makes 20-50%, and >50% IRAK4 degradation at 0.01, 0.1, and 1 μM in OCI-LY-10 cells, respectively[1].

References

[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.

PROTAC IRAK4 degrader-1Supplier

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Email: 3003855609@qq.com

Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com

Changzhou Bojia Biomedical Technology Co., Ltd.

Tel: 2122619822
Email: czbjpharma@126.com

ShenZhen Trendseen Biological Technology Co.,Ltd.

Tel: 13417589054 13417589054
Email: trendseenbio@gmail.com

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