Basic information Safety Supplier Related

DAPH

Basic information Safety Supplier Related

DAPH Basic information

Product Name:
DAPH
Synonyms:
  • DAPH-1 (DAPH
  • DAPH/CGP 52411
  • 4,5-Dianilinophthalimide, 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione, CGP 52411
  • 1H-Isoindole-1,3(2H)-dione, 5,6-bis(phenylamino)-
  • DAPH >=98% (HPLC), solid
CAS:
145915-58-8
MF:
C20H15N3O2
MW:
329.35
EINECS:
406-050-3
Mol File:
145915-58-8.mol
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DAPH Chemical Properties

Melting point:
199-202℃
Density 
1.374
storage temp. 
2-8°C
solubility 
DMSO: ~30 mg/mL
form 
solid
pka
9.06±0.20(Predicted)
color 
orange
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Safety Information

Safety Statements 
36/37
WGK Germany 
3
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DAPH Usage And Synthesis

Uses

CGP 52411 is a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitmuor activity. It may offer therapeutic agents for the treatment of hyperproliferative diseases.

Definition

ChEBI: 4,5-dianilinophthalimide is phthalimide substituted at the 4- and 5-positions by anilino groups. It has a role as a tyrosine kinase inhibitor and a geroprotector.

Biochem/physiol Actions

DAPH is an inhibitor of Aβ fibril formation; Protein tyrosine kinase inhibitor, specific for EGFR.

DAPHSupplier

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Email
info@adooq.com
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Email
sales@letopharm.com
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Email
info@efebio.com
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DAPH(145915-58-8)Related Product Information