Basic information Safety Supplier Related

PLASMINOGEN

Basic information Safety Supplier Related

PLASMINOGEN Basic information

Product Name:
PLASMINOGEN
Synonyms:
  • PLASMINOGEN, GLU-TYPE, HUMAN
  • PLASMINOGEN, GLU-TYPE, HUMAN PLASMA
  • PLASMINOGEN, HUMAN
  • PLASMINOGEN, HUMAN PLASMA
  • PLASMA TRYPSINOGEN, HUMAN
  • PROFIBRINOLYSIN
  • PROFIBRINOLYSIN, HUMAN
  • GLU-PLASMINOGEN (HUMAN)
CAS:
9001-91-6
MF:
NULL
MW:
0
EINECS:
232-641-9
Mol File:
Mol File
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PLASMINOGEN Chemical Properties

storage temp. 
-20°C
form 
lyophilized powder
biological source
human plasma
Water Solubility 
water: soluble
Specific Activity
7units/mg protein
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Safety Information

Hazard Codes 
B,Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
10-21

MSDS

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PLASMINOGEN Usage And Synthesis

Uses

Plasminogen is a single-chain glycoprotein found in human plasma and extracellular fluid. Certain activators, such as tissue plasminogen activator (tPA), convert plasminogen to its active form, plasmin. Plasminogen has been used to study its conversion into plasmin.

General Description

The plasminogen (PLG) gene is mapped to human chromosome 6q26. Plasminogen protein has a molecular weight of ?90kDa. It is composed of Pan-apple domain at the N-terminal, five kringle domains and serine protease domain at its C-terminal.

Biochem/physiol Actions

Plasminogen is the inactive precursor of the protease plasmin. Plasminogen is activated by the action of either tissue plasminogen activator (tPA), which primarily activates the fibrinolytic (thrombolytic) activity of plasmin, or urokinase plasminogen activator (uPA), which is associated with extracellular matrix remodeling and cell migration. Plasmin cleaves fibrin/fibrinogen and blood coagulation factors V/Va and VIII/VIIIa. It activates matrix metalloproteinases by cleaving the inactive proenzymes. It is also involved in the activation of some growth factors, such as vascular endothelial growth factor (VEGF) and transforming growth factor β (TGF-β).

PLASMINOGENSupplier

Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Email
sj_scrc@sinopharm.com
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Guangzhou LES biological Technology Co.,Ltd.
Tel
13672434928
Email
3307355104@qq.com
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Shanghai jingkang bioengineering co., ltd.
Tel
021-54721350 13524668266
Email
2881505714@qq.com