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EC 3.5.1.11

Basic information Safety Supplier Related

EC 3.5.1.11 Basic information

Product Name:
EC 3.5.1.11
Synonyms:
  • PENICILLIN ACYLASE
  • PENICILLIN AMIDASE
  • PENICILLIN AMIDASE, IMMOBILIZED ON EUPERGIT(R) C
  • E-PCA
  • EC 3.5.1.11
  • penicillin amidase from E. coli
  • Penicillin Amidase from E.Coli
  • Penicillin Amidase solution from Escherichia coli
CAS:
9014-06-6
MW:
0
EINECS:
232-753-8
Product Categories:
  • Hydrolases
  • Specialty Enzymes
Mol File:
Mol File
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EC 3.5.1.11 Chemical Properties

Density 
1.37[at 20℃]
vapor pressure 
0Pa at 25℃
storage temp. 
2-8°C
form 
lyophilized powder
color 
White to light brown
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Safety Information

Hazard Codes 
Xn
Risk Statements 
42/43
Safety Statements 
22-36/37
WGK Germany 
3
10

MSDS

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EC 3.5.1.11 Usage And Synthesis

Uses

Penicillin amidase was used to study its effect in release of fatty acid and HSL (homoserine lactone) from AHLs (N -acylhomoserine lactones) in degradation of antibiotics. It was used as positive control for assaying penicillin G acylase activity in the study of functional analysis of bile salt hydrolase and penicillin acylase family members in Lactobacillus sp. Penicillin amidase may be used for synthesis of 6-aminopenicillanic acid from penicillin-G and for the industrial production of β-lactam antibiotics.

General Description

Penicillin amidase is a periplasmic 80K heterodimer with A and B chains (209 and 566 amino acids, respectively). It is widely distributed among microorganisms, including bacteria, yeast and filamentous fungi. Among all the sources, the enzyme produced by E. coli is most well-characterized and common for industrial application.

Biochem/physiol Actions

The biosynthesis of Penicillin amidase in E. coli by hydrophobic protein chromatography is an inducible reaction which is regulated by metabolized carbon source (e.g. polyols, carboxylic acid etc.). It is also influenced by catabolite repression. It catalyzes the formation of amide bonds through an acyl-enzyme intermediate.

EC 3.5.1.11 Preparation Products And Raw materials

Preparation Products

EC 3.5.1.11Supplier

Shanghai Guchen Biotechnology Co., LTD Gold
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