4-(Hydroxymethyl)benzoic acid

Product Name: 4-(Hydroxymethyl)benzoic acid
CAS No.: 3006-96-0
Chemical Name: 4-(Hydroxymethyl)benzoic acid
Synonyms: HMBA;hb linker;HMBA LINKER;HMBA Novabiochem;RARECHEM AL BO 1443;Eprosartan USP RC E;Carbadox Impurity 3;4-methylolbenzoic acid;4-CARBOXYBENZYL ALCOHOL;Hydroxymethylbenzoicacid
CBNumber: CB1382486
Molecular Formula: C8H8O3
Formula Weight: 152.15
MOL File: 3006-96-0.mol

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4-(Hydroxymethyl)benzoic acid Property

Melting point:: 182-185 °C (lit.)
Boiling point:: 140-150 °C(Press: 9 Torr)
Density: 1.314±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO, Methanol
pka: 4.16±0.10(Predicted)
form: Coarse Fibers
color: White
BRN: 2690023
InChIKey: WWYFPDXEIFBNKE-UHFFFAOYSA-N
LogP: 0.930
CAS DataBase Reference: 3006-96-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
HS Code: 29181990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.51042
Product name: HMBA
Purity: Novabiochem?
Packaging: 5G
Price: $149
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.51042
Product name: HMBA
Purity: Novabiochem?
Packaging: 25g
Price: $593
Updated: 2024/03/01

Sigma-Aldrich

Product number: 382639
Product name: 4-(Hydroxymethyl)benzoic acid
Purity: 99%
Packaging: 1g
Price: $26
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1238262
Product name: Eprosartan Related Compound E
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 15mg
Price: $511
Updated: 2024/03/01

TCI Chemical

Product number: H0769
Product name: 4-Hydroxymethylbenzoic Acid
Purity: >98.0%(T)
Packaging: 10g
Price: $126
Updated: 2024/03/01

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4-(Hydroxymethyl)benzoic acid Chemical Properties,Usage,Production

Chemical Properties

Off-white solid

Uses

This linkage reagent for SPPS is essentially acid stable. It is useful in combination with Fmoc-amino acids. Its peptide esters are usually cleaved by basic or nucleophilic reagents, especially by ammonia in the preparation of peptide amides.

Uses

4-(Hydroxymethyl)benzoic Acid (Eprosartan USP Related Compound E) is an intermediate in the synthesis of Eprosartan (E590100), a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists used as an antihypertensive agent.

Uses

4-(Hydroxymethyl)benzoic Acid is an intermediate in the synthesis of Eprosartan (E590100), a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists used as an antihypertensive age nt.

Synthesis Reference(s)

Journal of the American Chemical Society, 107, p. 1365, 1985 DOI: 10.1021/ja00291a042

4-(Hydroxymethyl)benzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(Hydroxymethyl)benzoic acid Suppliers

Americas 1 Belgium 1 Canada 2 China 222 Europe 1 Germany 11 India 13 Japan 4 Switzerland 4 Ukraine 1 United Kingdom 15 United States 57 USA 1 Global 333

Huai'an Enrico Biotech Co., Ltd

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J & K SCIENTIFIC LTD.

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3B Pharmachem (Wuhan) International Co.,Ltd.

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TCI (Shanghai) Development Co., Ltd.

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Ark Pharm, Inc.

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Beijing HwrkChemical Technology Co., Ltd

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View Lastest Price from 4-(Hydroxymethyl)benzoic acid manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: 4-(Hydroxymethyl)benzoic acid 3006-96-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-12-04

Hebei Mojin Biotechnology Co., Ltd

Product: 4-(Hydroxymethyl)benzoic acid 3006-96-0
Price: US $100.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5000KG
Release date: 2023-08-15

Henan Aochuang Chemical Co.,Ltd.

Product: 4-(Hydroxymethyl)benzoic acid 3006-96-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-22

3006-96-0, 4-(Hydroxymethyl)benzoic acidRelated Search:

Tris(hydroxymethyl)nitromethane 2-(Trifluoromethyl)benzoic acid p-Toluic acid 4-Bromomethylbenzoic acid 4-(Aminomethyl)benzoic acid o-Toluic acid m-Toluic acid 4-(Chloromethyl)benzoic acid 4-(Hydroxymethyl)phenoxyacetic acid EPROSARTAN Epalrestat iMpurity α-Methylcinnamaldehyde ethyl 2-((E)-5-((E)-2-methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetate (2-CHLORO-ACETYLAMINO)-ACETIC ACID METHYL ESTER 3-(2-THIENYL)PROPIONIC ACID Eprosartan related coMpound C 3-Thiazolidineacetic acid, 4-oxo-2-thioxo-, methyl ester Rhodanine-3-acetic acid

HMBA

HMBA LINKER

4-CARBOXYBENZYL ALCOHOL

4-HYDROXYMETHYLBENZOIC ACID

RARECHEM AL BO 1443

HMBA LINKER,4-HYDROXYTHYLBENZOIC ACID

Hydroxymethylbenzoicacid

4-Hydroxythylbenzoic acid

hb linker

Benzoic acid, 4-(hydroxymethyl)-

4-(HYDROXYMETHYL)BENZOIC ACID HMBA LINKER 98%

Benzoic acid, 4-(hydroxymethyl)- (9CI)

4-methylolbenzoic acid

4-(HYDROXYMETHYL)BENZOIC ACID (HMBA LINKER)

4-(Hydroxymethyl)benzoic acid, 98+%

Ecamsule Related Compound B (50 mg) (4-(hydroxymethyl)benzoic acid)

HMBA Linker 4-(HydroxyMethyl)benzoic acid

Eprosartan USP RC E

4-HydroxyMrthylbenzoic acid

Eprosartan Impurity 5(Eprosartan USP RC E)

Eprosartan related coMpound E

EcaMsule Related CoMpound B

Eprosartan Related Compound E (15 mg) (4-(hydroxymethyl)benzoic acid)

4-(Hydroxymethyl)benzoic acid≥ 99% (HPLC)

HMBA Novabiochem

Eprosartan USP Related Compound E

4-(hydroxymethyl)benzoate

4-HydroxymethylbenzoicAcid&gt

HMBA Linker 4-(Hydroxymethyl)benzoic acid,98%

4-(Hydroxymethyl)benzoic acid,0.98

TIANFUCHEM--3006-96-0--4-(Hydroxymethyl)benzoic acid factory price

HMBA Linker (4-(Hydroxymethyl)benzoic Acid) extrapure, 99%

Eprosartan Related Compound E (4-(hydroxymethyl)benzoic acid) (1238262)

4-(Hydroxymethyl)benzoicaci

Carbadox Impurity 3

3006-96-0

HOCH2C6H4CO2H

Organic Building Blocks

Linkers

Combinatrial Chemistry

C8

Carboxylic Acids

Carbonyl Compounds

Building Blocks

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts

Organic acids

Linkers for Solid Phase Synthesis

Combinatorial Chemistry

Linkers

Synthetic Organic Chemistry

Biochemics

Bifunctional CrosslinkersCarbonyl Compounds

C8

Carboxylic Acids

Peptide Synthesis