Propargyl-PEG4-(CH2)3-methyl ester

Product Name: Propargyl-PEG4-(CH2)3-methyl ester
CAS No.: 1872433-63-0
Chemical Name: Propargyl-PEG4-(CH2)3-methyl ester
Synonyms: Propargyl-PEG4-CH2-methyl ester;Propargyl-PEG4-(CH2)3-methyl este;Propargyl-PEG4-(CH2)3-methyl ester;5,8,11,14-Tetraoxaheptadec-16-ynoic acid, methyl ester
CBNumber: CB23163108
Molecular Formula: C14H24O6
Formula Weight: 288.34
MOL File: 1872433-63-0.mol

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Propargyl-PEG4-(CH2)3-methyl ester Property

Boiling point:: 354.3±37.0 °C(Predicted)
Density: 1.058±0.06 g/cm3(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23109
Product name: Propargyl-PEG4-(CH2)3-methylester
Purity: 98%
Packaging: 100mg
Price: $350
Updated: 2021/12/16

BroadPharm

Product number: BP-23109
Product name: Propargyl-PEG4-(CH2)3-methylester
Purity: 98%
Packaging: 250mg
Price: $580
Updated: 2021/12/16

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Propargyl-PEG4-(CH2)3-methyl ester Chemical Properties,Usage,Production

Description

Propargyl-PEG4-(CH2)3-methyl ester consists of a propargyl group and a methyl ester. The propargyl group reacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions to form a stable triazole linkage. Under strong basic condition, methyl ester can be hydrolyzed.

Uses

Propargyl-PEG4-CH2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG4-CH2-methyl ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Propargyl-PEG4-(CH2)3-methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG4-(CH2)3-methyl ester Suppliers

China 10 United States 3 Global 13

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
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Aladdin Scientific

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Email: tp@aladdinsci.com
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Combi-Blocks Inc.

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Email: sales@combi-blocks.com
Country: United States
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Propargyl-PEG4-(CH2)3-methyl ester

Propargyl-PEG4-CH2-methyl ester

Propargyl-PEG4-(CH2)3-methyl este

5,8,11,14-Tetraoxaheptadec-16-ynoic acid, methyl ester

1872433-63-0