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Pomalidomide-PEG1-azide

Product Name
Pomalidomide-PEG1-azide
CAS No.
2133360-04-8
Chemical Name
Pomalidomide-PEG1-azide
Synonyms
N3-PEG1-CH2CO-Poma;Pomalidomide-PEG1-azide;Pomalidomide-NH-CO-PEG1-N3;2-(2-Azidoethoxy)-N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxoisoindolin-4-yl]acetamide;Acetamide, 2-(2-azidoethoxy)-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
CBNumber
CB24813989
Molecular Formula
C17H16N6O6
Formula Weight
400.35
MOL File
2133360-04-8.mol
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Pomalidomide-PEG1-azide Property

storage temp. 
2-8°C
solubility 
DMSO : 62.5 mg/mL (156.11 mM; ultrasonic and warming and heat to 60°C)
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
903825
Product name
Pomalidomide-PEG1-azide
Packaging
50MG
Price
$904
Updated
2023/06/20
Iris Biotech GmbH
Product number
PTC1520
Product name
Pomalidomid-PEG1-N3
Packaging
50mg
Price
$607.5
Updated
2021/12/16
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Pomalidomide-PEG1-azide Chemical Properties,Usage,Production

Uses

Protein degrader builiding block Pomalidomide-PEG1-azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant azide for click chemistry with a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation When used with other protein degrader building blocks with a pendant azide group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

Pomalidomide-PEG1-azide Preparation Products And Raw materials

Raw materials

Preparation Products

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Pomalidomide-PEG1-azide Suppliers

Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4824
Advantage
58
Jilin Province Woda Biotechnology Co., Ltd.
Tel
13504435624
Email
1927928688@qq.com
Country
China
ProdList
1388
Advantage
58
Shaanxi borno biotechnology co., LTD
Tel
+86-13759708231
Email
asherw9@hotmail.com
Country
China
ProdList
2350
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
4008210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
54986
Advantage
58
Xi'an Qiyue Biotechnology Co., Ltd.
Tel
400-400-6966-012-012 17778955912
Email
2957605606@qq.com
Country
China
ProdList
2535
Advantage
58
Changzhou Bojia Biomedical Technology Co., Ltd.
Tel
2122619822
Email
czbjpharma@126.com
Country
China
ProdList
18478
Advantage
58
Yutong Pharmaceutical Technology (Suzhou) Co., Ltd.
Tel
15851462628 15851462628
Email
2680463261@qq.com
Country
China
ProdList
5008
Advantage
58
Henan Alpha Chemical Co., Ltd.
Tel
0371-55013243 15324716602
Email
2853979810@qq.com
Country
China
ProdList
10018
Advantage
58
ShenZhen Trendseen Biological Technology Co.,Ltd.
Tel
13417589054 13417589054
Email
trendseenbio@gmail.com
Country
China
ProdList
9470
Advantage
58
Shanghai Easy CDMO Co.,Ltd
Tel
021-61734564
Email
August@easycdmo.com
Country
China
ProdList
10030
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50464
Advantage
58
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Email
syeu@accelachem.com
Country
China
ProdList
11710
Advantage
58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
+86-18521732826
Email
market@aladdin-e.com
Country
China
ProdList
48461
Advantage
58
Jilin Chinese Academy of Sciences-yanshen Technology
Tel
18143011203
Email
ET-market@chemextension.com
Country
China
ProdList
25812
Advantage
58
Xi‘an Deeptech Biotechnology Co.,LTD
Tel
+86-15114901355 +86-15114901355
Email
15114901355@163.com
Country
China
ProdList
189
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd
Tel
13915962545
Email
2881759498@qq.com
Country
China
ProdList
2016
Advantage
58
Xian confluore Biological Technology Co., Ltd.
Tel
+86-15680926068 +86-15680926068
Email
1924344760@confluore.cn
Country
China
ProdList
2995
Advantage
58
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View Lastest Price from Pomalidomide-PEG1-azide manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Pomalidomide-NH-CO-PEG1-N3 2133360-04-8
Price
US $0.00/mg
Min. Order
100mg
Purity
>99.00%
Supply Ability
100mg
Release date
2024-04-01