Pomalidomide-PEG1-azide

Product Name: Pomalidomide-PEG1-azide
CAS No.: 2133360-04-8
Chemical Name: Pomalidomide-PEG1-azide
Synonyms: N3-PEG1-CH2CO-Poma;Pomalidomide-PEG1-azide;Pomalidomide-NH-CO-PEG1-N3;2-(2-Azidoethoxy)-N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxoisoindolin-4-yl]acetamide;Acetamide, 2-(2-azidoethoxy)-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
CBNumber: CB24813989
Molecular Formula: C17H16N6O6
Formula Weight: 400.35
MOL File: 2133360-04-8.mol

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Pomalidomide-PEG1-azide Property

storage temp.: 2-8°C
solubility: DMSO : 62.5 mg/mL (156.11 mM; ultrasonic and warming and heat to 60°C)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 903825
Product name: Pomalidomide-PEG1-azide
Packaging: 50MG
Price: $904
Updated: 2023/06/20

Iris Biotech GmbH

Product number: PTC1520
Product name: Pomalidomid-PEG1-N3
Packaging: 50mg
Price: $607.5
Updated: 2021/12/16

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Pomalidomide-PEG1-azide Chemical Properties,Usage,Production

Uses

Protein degrader builiding block Pomalidomide-PEG1-azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant azide for click chemistry with a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation When used with other protein degrader building blocks with a pendant azide group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

Pomalidomide-PEG1-azide Preparation Products And Raw materials

Raw materials

Preparation Products

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Pomalidomide-PEG1-azide Suppliers

China 18 United States 3 Global 21

Sigma-Aldrich

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View Lastest Price from Pomalidomide-PEG1-azide manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Pomalidomide-NH-CO-PEG1-N3 2133360-04-8
Price: US $0.00/mg
Min. Order: 100mg
Purity: >99.00%
Supply Ability: 100mg
Release date: 2024-04-01

2133360-04-8, Pomalidomide-PEG1-azideRelated Search:

Pomalidomide-PEG3-N3 E3 ligase Ligand-Linker Conjugates 50 Pomalidomide-PEG3-CO2H Pomalidomide-PEG4-azide Pomalidomide-PEG2-butyl iodide E3 Ligase Ligand-Linker Conjugates 22 4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Pomalidomide-PEG4-CO2H E3 Ligase Ligand-Linker Conjugates 1 POMALIDOMIDE-PEG2-CO2H Pomalidomide-PEG5-CO2H POMALIDOMIDE-PEG1-CO2H Pomalidomide-O-C4-NH2 Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]- Pomalidomide-PEG6-butyl iodide Pomalidomide-PEG2-N3 Pomalidomide-NH-CO-PEG6-N3 Pomalidomide-PEG5-N3

Pomalidomide-PEG1-azide

Pomalidomide-NH-CO-PEG1-N3

2-(2-Azidoethoxy)-N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxoisoindolin-4-yl]acetamide

N3-PEG1-CH2CO-Poma

Acetamide, 2-(2-azidoethoxy)-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-

2133360-04-8

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