ChemicalBook > CAS DataBase List > 1-Boc-4-methylpiperidine-4-carboxylic acid

1-Boc-4-methylpiperidine-4-carboxylic acid

Product Name
1-Boc-4-methylpiperidine-4-carboxylic acid
CAS No.
189321-63-9
Chemical Name
1-Boc-4-methylpiperidine-4-carboxylic acid
Synonyms
1-Boc-4-MethyL;CHEMBRDG-BB 4002933;-4-piperidinecarboxyL;N-BOC-4-METHYL ISONIPECOTIC ACID;1-BOC-4-METHYL-ISONIPECOTIC ACID;4-METHYL-4-CARBOXY-1-N-BOC-PIPERIDINE;N-BOC-4-METHYL-4-PIPERIDINECARBOXYLIC ACID;1-Boc-4-methyl-4-piperidinecarboxylic Acid;1-BOC-4-METHYL-PIPERIDINE-4-CARBOXYLIC ACID;N-Boc-4-Methyl-piperidine-4-carboxylic acid/
CBNumber
CB4192851
Molecular Formula
C12H21NO4
Formula Weight
243.3
MOL File
189321-63-9.mol
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1-Boc-4-methylpiperidine-4-carboxylic acid Property

Boiling point:
354.3±35.0 °C(Predicted)
Density 
1.129±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
4.69±0.20(Predicted)
InChI
InChI=1S/C12H21NO4/c1-11(2,3)17-10(16)13-7-5-12(4,6-8-13)9(14)15/h5-8H2,1-4H3,(H,14,15)
InChIKey
OKBNEDPOUYRYNP-UHFFFAOYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCC(C)(C(O)=O)CC1
CAS DataBase Reference
189321-63-9(CAS DataBase Reference)
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Safety

RIDADR 
UN2811
HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B699548
Product name
1-(tert-Butoxycarbonyl)-4-methylpiperidine-4-carboxylicAcid
Packaging
2.5mg
Price
$45
Updated
2021/12/16
TRC
Product number
B699548
Product name
1-(tert-Butoxycarbonyl)-4-methylpiperidine-4-carboxylicAcid
Packaging
5mg
Price
$60
Updated
2021/12/16
ChemScene
Product number
CS-M0704
Product name
1-(tert-butoxycarbonyl)-4-methylpiperidine-4-carboxylicacid
Purity
98.99%
Packaging
5g
Price
$61
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB123231
Product name
1-(tert-Butoxycarbonyl)-4-methylpiperidine-4-carboxylic acid
Packaging
250mg
Price
$57.5
Updated
2021/12/16
AK Scientific
Product number
W4077
Product name
1-Boc-4-Methylpiperidine-4-carboxylicacid
Packaging
250mg
Price
$73
Updated
2021/12/16
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1-Boc-4-methylpiperidine-4-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

White to Light yellow powder to crystal

Synthesis

A mixture of Ethyl N-Boc-4-methylpiperidine-4-carboxylate (4.1 g, 15.1mmol) and lithium hydroxide (2.17g, 90.6mmol) in methanol (3OmL)ZH2O (2OmL) was stirred at a temperature of about 25 ℃ for 16h. After evaporation to dryness, the residue was partitioned between DCM and brine. The organic layer was separated, dried (MgSO4), filtered, and concentrated under reduced pressure to provide 3.38g of 1-Boc-4-methylpiperidine-4-carboxylic acid as a white solid (yield 92.0 percent).

1-Boc-4-methylpiperidine-4-carboxylic acid Preparation Products And Raw materials

Raw materials

Ethanol Di-tert-butyl dicarbonate Diisopropylamine Lithium hydroxide monohydrate Tetrahydrofuran Ammonium chloride Ethyl 4-piperidinecarboxylate Ethyl acetate Hydrochloric acid Dichloromethane Methanol PETROLEUM ETHER Iodomethane n-Butyllithium

Preparation Products

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View Lastest Price from 1-Boc-4-methylpiperidine-4-carboxylic acid manufacturers

Career Henan Chemical Co
Product
1-Boc-4-methylpiperidine-4-carboxylic acid 189321-63-9
Price
US $2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customise
Release date
2018-08-09

189321-63-9, 1-Boc-4-methylpiperidine-4-carboxylic acidRelated Search:

o-Toluic acid p-Toluic acid Triacetonediamine 2,2,6,6-Tetramethyl-4-piperidinol tert-Butyl carbazate 1,2,2,6,6-Pentamethyl-4-piperidinol Isonipecotic acid BOC-4-PHENYLPIPERIDINE-4-CARBOXYLIC ACID 1-BOC-4-ETHYL-4-PIPERIDINECARBOXYLIC ACID Ethyl N-Boc-4-methylpiperidine-4-carboxylate N-Boc-3-Methylnipecotic acid ethyl ester 1-N-Boc-3-Methylpiperidine-3-carboxylic acid BOC-4-CYCLOHEXYL-PIPERIDINE-4-CARBOXYLIC ACID N-BOC-4-(P-FLUOROPHENYL)-4-PIPERIDINECARBOXYLIC ACID 1,4-Piperidinedicarboxylic acid, 4-(2-propen-1-yl)-, 1-(1,1-dimethylethyl) ester METHYL 4-AMINOMETHYL-1-BOC-PIPERIDINE-4-CARBOXYLATE N-BOC-4-BENZYL-4-PIPERIDINECARBOXYLIC ACID N-BOC-4-(P-CHLOROPHENYL)-4-PIPERIDINE CARBOXYLIC ACID

  • N-BOC-4-METHYL ISONIPECOTIC ACID
  • N-BOC-4-METHYL-4-METHYLPIPERIDINECARBOXYLIC ACID
  • N-BOC-4-METHYL-4-PIPERIDINECARBOXYLIC ACID
  • CHEMBRDG-BB 4002933
  • 4-METHYL-4-CARBOXY-1-N-BOC-PIPERIDINE
  • 4-METHYL-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-TERT-BUTYL ESTER
  • 1-BOC-4-METHYL-PIPERIDINE-4-CARBOXYLIC ACID
  • 1-Boc-4-methyl-4-piperidinecarboxylic Acid
  • 1-(tert-Butoxycarbonyl)-4-methylpiperidine-4-carboxylic acid
  • N-BOC-4-METHYL-4-METHYLPIPERIDINECARBOXYLIC ACIDN-BOC-4-METHYL ISONIPECOTIC ACID
  • 1-N-Boc-4-methyl-piperidine-4-carboxylic acid
  • 1-BOC-4-METHYL-ISONIPECOTIC ACID
  • 1,4-Piperidinedicarboxylic acid, 4-methyl-, 1-(1,1-dimethylethyl) ester
  • 1,4-piperidinedicarboxylic acid, 4-methyl-, 1-(1,1-dimethy
  • 1-Boc-4-methyl-piperidine-4-carboxylic acid ,98%
  • 1-(tert-butoxycarbonyl)-4-methylpiperidine-4-carboxylic acid(SALTDATA: FREE)
  • N-Boc-4-Methyl-piperidine-4-carboxylic acid/
  • 1-tert-butoxycarbonyl-4-methyl-isonipecotic acid
  • 4-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylic acid
  • 1-(tert-butoxy-oxomethyl)-4-methyl-4-piperidinecarboxylic acid
  • 1-Boc-4-MethyL
  • -4-piperidinecarboxyL
  • 4-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylicaci
  • 1-Boc-4-methylpiperidine-4-carboxylic acid USP/EP/BP
  • 1,4-Piperidinedicarboxylic acid, 4-methyl-, 1-(1,1-dimethylethyl) ester (9CI, ACI)
  • 4-methyl-1,4-Piperidinedicarboxylic acid 1-(1,1-dimethylethyl) ester (9CI ACI)
  • 189321-63-9
  • API intermediates
  • Amino Acids and Derivatives
  • Heterocycles
  • Pyridines