ChemicalBook > CAS DataBase List > 4-Iodoaniline

4-Iodoaniline

Product Name
4-Iodoaniline
CAS No.
540-37-4
Chemical Name
4-Iodoaniline
Synonyms
BENZENAMINE, 4-IODO-;P-IODOANILINE;4-iodobenzenamine;4-IodoaniL;4-LODANILINE;4-IODOANILINE;4-iodo-anilin;p-iodo-anilin;p-lodoaniline;Iodine aniline
CBNumber
CB5110557
Molecular Formula
C6H6IN
Formula Weight
219.02
MOL File
540-37-4.mol
More
Less

4-Iodoaniline Property

Melting point:
61-63 °C(lit.)
Boiling point:
268.7±23.0 °C(Predicted)
Density 
1.8155 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
H2O: slightly soluble
form 
Crystalline Powder or Needles
pka
3.81(at 25℃)
color 
Beige to grayish-brown
Water Solubility 
Slightly soluble in water.Soluble in chloroform, methanol.
Sensitive 
Light Sensitive
Merck 
14,5027
BRN 
774101
InChIKey
VLVCDUSVTXIWGW-UHFFFAOYSA-N
CAS DataBase Reference
540-37-4(CAS DataBase Reference)
NIST Chemistry Reference
Benzenamine, 4-iodo-(540-37-4)
EPA Substance Registry System
Benzenamine, 4-iodo- (540-37-4)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38-20/21/22
Safety Statements 
26-36/37/39-36
RIDADR 
2811
WGK Germany 
3
RTECS 
BY3850000
8
Hazard Note 
Harmful/Irritant
TSCA 
T
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29214210
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
129364
Product name
4-Iodoaniline
Purity
98%
Packaging
25g
Price
$59
Updated
2024/03/01
Sigma-Aldrich
Product number
129364
Product name
4-Iodoaniline
Purity
98%
Packaging
100g
Price
$73.6
Updated
2024/03/01
TCI Chemical
Product number
I0048
Product name
4-Iodoaniline
Packaging
25G
Price
$68
Updated
2024/03/01
TCI Chemical
Product number
I0048
Product name
4-Iodoaniline
Packaging
250G
Price
$215
Updated
2022/04/27
Alfa Aesar
Product number
B21936
Product name
4-Iodoaniline, 98%
Packaging
50g
Price
$73.9
Updated
2024/03/01
More
Less

4-Iodoaniline Chemical Properties,Usage,Production

Chemical Properties

beige to greyish-brown crystalline powder. soluble in alcohol, ether and chloroform, slightly soluble in water.

Uses

suzuki reaction

Uses

4-dehydroanilinium ion, a stable distonic isomer of ionized aniline, by collision-activated dissociation of protonated 4-iodoaniline. Palladium-catalyzed carbonylation of 4-iodoaniline gave the corresponding four- armed star polybenzamides. 4-Iodoaniline is a iodine substituted aniline that is widely used as chemical intermediates in the manufacturing of dyes and drugs. 4-Iodoaniline was used to prepare phenyl functionalized graphene oxide (I-Ph-GO).

Uses

4-Iodoaniline is a iodine substituted aniline that is widely used as chemical intermediates in the manufacturing of pesticides, dyes and drugs. 4-Iodoaniline was shown to be a more potent nephrotoxica nt in vitro than other anilines.

Preparation

4-Iodoaniline is obtained by the reaction of aniline and iodine in the presence of sodium bicarbonate. Add aniline and sodium bicarbonate to water and slowly add crushed iodine in stages with vigorous stirring. If the reaction solution is yellow, add a little sodium bisulfite to make it discolor, then filter and get the crude product. Then the product is recrystallized by ethanol to obtain 4-Iodoaniline.

General Description

4-Iodoaniline is the most potent methaemoglobin former.

Purification Methods

Crystallise it from pet ether (b 60-80o) by refluxing, then cool it in an ice-salt bath freezing mixture. Dry it in air. Alternatively, crystallise it from EtOH and dry it in vacuo for 6hours at 40o [Edidin et al. J Am Chem Soc 109 3945 1987]. The N-acetyl derivative has m 184o (from MeOH). [Beilstein 12 IV 1544.]

4-Iodoaniline Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-Iodoaniline Suppliers

Jingjiang Sanjing Biotechnology Co., Ltd.
Tel
15250805028
Fax
QQ:1048979734
Email
1048979734@qq.com
Country
China
ProdList
296
Advantage
58
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.
Tel
133-96369453 18678026865
Fax
0536-2101172
Email
sdfantai@163.com
Country
China
ProdList
851
Advantage
58
SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
Fax
0838-5675535
Email
nbcxkj@126.com
Country
China
ProdList
668
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2341
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7508
Advantage
55
More
Less

View Lastest Price from 4-Iodoaniline manufacturers

airuikechemical co., ltd.
Product
4-Iodoaniline 540-37-4
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-03-26
Henan Fengda Chemical Co., Ltd
Product
4-Iodoaniline 540-37-4
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-23
Hebei Guanlang Biotechnology Co., Ltd.
Product
4-Iodoaniline 540-37-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2023-04-19

540-37-4, 4-IodoanilineRelated Search:


  • BENZENAMINE, 4-IODO-
  • 1-amino-4-iodobenzene
  • 4-IODOANILINE
  • 4-LODANILINE
  • P-IODOANILINE
  • 4-iodo-anilin
  • 4-iodo-benzenamin
  • 4-iodobenzenamine
  • 4-iodo-Benzenamine
  • p-lodoaniline
  • 1-Iodo-4-aminobenzene
  • p-Aminoiodobenzene
  • 4-Aminophenyl iodide
  • 4-Iodoaniline,99%
  • 4-IodobenzeneaMine
  • 4-Iodoaniline, 99% 25GR
  • The iodine aniline
  • Iodine aniline
  • 4-Iodoaniline≥ 98% (GC)
  • 4-IodoaniL
  • 4-Iodo-phenylamine
  • Aniline, 4-iodo-
  • Aniline, p-iodo-
  • Benzenamine,4-Iodoaniline
  • p-Aminophenyl iodide
  • p-aminophenyliodide
  • p-iodo-anilin
  • 4-Indo Aniline
  • IODOANILINE, 4-
  • 4-Iodoaniline,~98%
  • 4-Iodoaniline, 98%, for synthesis
  • 4-Iodoaniline&gt
  • 4 - iodine aniline
  • 4-Iodoaniline ISO 9001:2015 REACH
  • RSYY(Apremilast)-8
  • 4 Iodoaniline (P-Iodoaniline,4-Iodobenzenamine)
  • 540-37-4
  • IC6H4NH2
  • IC6H6N
  • C2 to C6
  • Building Blocks
  • Amines
  • AMINE
  • Organic Building Blocks
  • Nitrogen Compounds
  • Building Blocks
  • C6
  • Chemical Synthesis
  • Nitrogen Compounds
  • Organic Building Blocks
  • Pharmaceutical Intermediates
  • Anilines, Aromatic Amines and Nitro Compounds
  • Amines
  • API intermediates
  • Anilines, Amides & Amines
  • Iodine Compounds
  • C2 to C6
  • Nitrogen Compounds