4-Iodoaniline
- Product Name
- 4-Iodoaniline
- CAS No.
- 540-37-4
- Chemical Name
- 4-Iodoaniline
- Synonyms
- BENZENAMINE, 4-IODO-;P-IODOANILINE;4-iodobenzenamine;4-IodoaniL;4-LODANILINE;4-IODOANILINE;4-iodo-anilin;p-iodo-anilin;p－lodoaniline;Iodine aniline
- CBNumber
- CB5110557
- Molecular Formula
- C6H6IN
- Formula Weight
- 219.02
- MOL File
- 540-37-4.mol
4-Iodoaniline Property
- Melting point:
- 61-63 °C(lit.)
- Boiling point:
- 268.7±23.0 °C(Predicted)
- Density
- 1.8155 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- H2O: slightly soluble
- form
- Crystalline Powder or Needles
- pka
- 3.81(at 25℃)
- color
- Beige to grayish-brown
- Water Solubility
- Slightly soluble in water.Soluble in chloroform, methanol.
- Sensitive
- Light Sensitive
- Merck
- 14,5027
- BRN
- 774101
- InChIKey
- VLVCDUSVTXIWGW-UHFFFAOYSA-N
- CAS DataBase Reference
- 540-37-4(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzenamine, 4-iodo-(540-37-4)
- EPA Substance Registry System
- Benzenamine, 4-iodo- (540-37-4)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38-20/21/22
- Safety Statements
- 26-36/37/39-36
- RIDADR
- 2811
- WGK Germany
- 3
- RTECS
- BY3850000
- F
- 8
- Hazard Note
- Harmful/Irritant
- TSCA
- T
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29214210
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 129364
- Product name
- 4-Iodoaniline
- Purity
- 98%
- Packaging
- 25g
- Price
- $59
- Updated
- 2024/03/01
- Product number
- 129364
- Product name
- 4-Iodoaniline
- Purity
- 98%
- Packaging
- 100g
- Price
- $73.6
- Updated
- 2024/03/01
- Product number
- I0048
- Product name
- 4-Iodoaniline
- Packaging
- 25G
- Price
- $68
- Updated
- 2024/03/01
- Product number
- I0048
- Product name
- 4-Iodoaniline
- Packaging
- 250G
- Price
- $215
- Updated
- 2022/04/27
- Product number
- B21936
- Product name
- 4-Iodoaniline, 98%
- Packaging
- 50g
- Price
- $73.9
- Updated
- 2024/03/01
4-Iodoaniline Chemical Properties,Usage,Production
Chemical Properties
beige to greyish-brown crystalline powder. soluble in alcohol, ether and chloroform, slightly soluble in water.
Uses
suzuki reaction
Uses
4-dehydroanilinium ion, a stable distonic isomer of ionized aniline, by collision-activated dissociation of protonated 4-iodoaniline. Palladium-catalyzed carbonylation of 4-iodoaniline gave the corresponding four- armed star polybenzamides. 4-Iodoaniline is a iodine substituted aniline that is widely used as chemical intermediates in the manufacturing of dyes and drugs. 4-Iodoaniline was used to prepare phenyl functionalized graphene oxide (I-Ph-GO).
Uses
4-Iodoaniline is a iodine substituted aniline that is widely used as chemical intermediates in the manufacturing of pesticides, dyes and drugs. 4-Iodoaniline was shown to be a more potent nephrotoxica nt in vitro than other anilines.
Preparation
4-Iodoaniline is obtained by the reaction of aniline and iodine in the presence of sodium bicarbonate. Add aniline and sodium bicarbonate to water and slowly add crushed iodine in stages with vigorous stirring. If the reaction solution is yellow, add a little sodium bisulfite to make it discolor, then filter and get the crude product. Then the product is recrystallized by ethanol to obtain 4-Iodoaniline.
General Description
4-Iodoaniline is the most potent methaemoglobin former.
Purification Methods
Crystallise it from pet ether (b 60-80o) by refluxing, then cool it in an ice-salt bath freezing mixture. Dry it in air. Alternatively, crystallise it from EtOH and dry it in vacuo for 6hours at 40o [Edidin et al. J Am Chem Soc 109 3945 1987]. The N-acetyl derivative has m 184o (from MeOH). [Beilstein 12 IV 1544.]
4-Iodoaniline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Iodoaniline manufacturers
- Product
- 4-IODOANILINE 540-37-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2024-10-30
- Product
- 4-Iodoaniline 540-37-4
- Price
- US $75.00-20.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-06-03
- Product
- 4-Iodoaniline 540-37-4
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-08