ChemicalBook > CAS DataBase List > Succinic anhydride

Succinic anhydride

Product Name
Succinic anhydride
CAS No.
108-30-5
Chemical Name
Succinic anhydride
Synonyms
SAN;succinic;SAA;DIHYDRO-2,5-FURANDIONE;SUCCINIC ACID ANHYDRIDE;SAA1;Dihydro-furan-2,5-dione;BUTANEDIOIC ANHYDRIDE;Bernsteinsaure-anhydrid;Serum amyloid A protein
CBNumber
CB5166246
Molecular Formula
C4H4O3
Formula Weight
100.07
MOL File
108-30-5.mol
More
Less

Succinic anhydride Property

Melting point:
118-120 °C (lit.)
Boiling point:
261 °C (lit.)
Density 
1,572 g/cm3
vapor density 
3.5 (vs air)
vapor pressure 
1 mm Hg ( 92 °C)
refractive index 
1.4688 (estimate)
Flash point:
157°C
storage temp. 
Store below +30°C.
solubility 
62.9g/l Hydrolysis
form 
Solid
pka
4.67[at 20 ℃]
color 
White to Off-White
Specific Gravity
1.2340 (20℃)
PH
2.7 (10g/l, H2O)
Water Solubility 
<0.1 g/100 mL at 21 ºC (decomposes)
Sensitive 
Moisture Sensitive
Merck 
14,8870
BRN 
108441
Stability:
Stable. Incompatible with oxidising agents, strong acids, strong bases, alcohols, amines. Avoid exposure to water or moisture.
InChIKey
RINCXYDBBGOEEQ-UHFFFAOYSA-N
LogP
2.44 at 40℃
CAS DataBase Reference
108-30-5(CAS DataBase Reference)
NIST Chemistry Reference
2,5-Furandione, dihydro-(108-30-5)
IARC
3 (Vol. 15, Sup 7) 1987
EPA Substance Registry System
Succinic anhydride (108-30-5)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37-22
Safety Statements 
25-46
RIDADR 
UN 3261 8 / PGII
WGK Germany 
1
RTECS 
WN0875000
F 
21
Autoignition Temperature
480 °C
TSCA 
Yes
HS Code 
29171990
Hazardous Substances Data
108-30-5(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 1510 mg/kg
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H290May be corrosive to metals

Precautionary statements

P234Keep only in original container.

P390Absorb spillage to prevent material damage.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.00683
Product name
Succinic anhydride
Purity
for synthesis
Packaging
100g
Price
$40
Updated
2024/03/01
Sigma-Aldrich
Product number
8.00683
Product name
Succinic anhydride
Purity
for synthesis
Packaging
500g
Price
$55.5
Updated
2024/03/01
Sigma-Aldrich
Product number
8.00683
Product name
Succinic anhydride
Purity
for synthesis
Packaging
1kg
Price
$80.7
Updated
2024/03/01
Sigma-Aldrich
Product number
8.00683
Product name
Succinic anhydride
Purity
for synthesis
Packaging
50kg
Price
$1690
Updated
2024/03/01
Sigma-Aldrich
Product number
239690
Product name
Succinic anhydride
Purity
≥99% (GC)
Packaging
50g
Price
$54.2
Updated
2024/03/01
More
Less

Succinic anhydride Chemical Properties,Usage,Production

Description

Succinic anhydride, also called di hydro - 2,5- furandione , is an organic compound with the molecular formula C4H4O3.This colorless solid is the acid anhydride of succinic acid.

Chemical Properties

Succinic anhydride is an odourless, colourless needle-like or white crystalline solid natural product. Molecular formula C4H4O3, molecular weight 100.07 g/mol, relative density 1.503, melting point 237 °F. 239 °F at 5 mmHg, 239 °F at 198 °F and 1 mmHg. Soluble in chloroform, carbon tetrachloride, and ethanol; very slightly soluble in ether and water (insoluble in water). Moderately toxic and irritating, emits pungent and irritating fumes when heated to decomposition.

Chemical Properties

fine white crystalline solid

Uses

It was used in the preparation of covalently cross-linked oxidized-alginate/N-succinyl-chitosan hydrogels, as injectable systems towards tissue engineering.It was also used in preparing functionalized oxide surfaces on a chip.

Uses

Succinic Anhydride is an acidulant that hydrolyzes very slowly to succinic acid in water. it has thermal stability and a low melting point of 118°c which permits it to be used in products at compara- tively low temperatures. it is used as a leavening acidulant for bak- ing powder.

Uses

Succinic Anhydride is a useful compound in the paper manufacturing process.

Definition

ChEBI: Succinic anhydride is a cyclic dicarboxylic anhydride and a tetrahydrofurandione. It is functionally related to a succinic acid.

Application

Alkyl succinic anhydride (ASA) is used as a sizing agent or wet strength additive in paper production.

Production Methods

The compound is produced from succinic anhydride and hydrogen peroxide . This material must be stabilized by using a dehydrating agent such as disodium sulfate or magnesium sulfate.

Preparation

A solution of succinic acid (500 mg, 42 mmol) and triethylamine (1.23 mL, 42 mmol) in anhydrous THF (120 mL) was allowed to react with triphosgene (42 mg, 7.0 mmol) at ice-water temperature for 10 min. The reaction mixture was subsequently stirred for a further 15 min at room temperature. The solution was then filtered, and the filtrate was concentrated to dryness. The residue was crystallized from ethyl acetate to afford the desired product as white crystals (370 mg, 85%).

Synthesis Reference(s)

Synthetic Communications, 23, p. 419, 1993 DOI: 10.1080/00397919308009796

General Description

Succinic anhydride is a cyclic anhydride of succinic acid with a five-membered ring. It is widely used in the manufacture of polymeric materials, pharmaceuticals, agrochemicals, dyes, surface-active agents, and organic flame-retardant materials. It also finds application as a cross-linking agent in ion-exchange membranes and a curing agent for epoxy resins.

General Description

Colorless needles or white crystalline solid. Melting point 237°F. Sublimes at 239°F at 5 mm Hg pressure; and at 198°F and 1 mm Hg pressure. Moderately toxic and an irritant.

Air & Water Reactions

Reacts slowly with water. Insoluble in water.

Reactivity Profile

Succinic anhydride reacts exothermically with water. Reactions are usually slow, but might become violent if local heating accelerates their rate. Acids accelerate the reaction with water. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases.

Fire Hazard

Flash point data for Succinic anhydride are not available, however, Succinic anhydride is probably combustible.

Flammability and Explosibility

Not classified

Materials Uses

Succinic anhydride can be used:
(1) In the preparation of covalently cross-linked oxidized-alginate/N-succinyl-chitosan hydrogels, as injectable systems towards tissue engineering.
(2) In preparing functionalized oxide surfaces on a chip.
(3) As a starting material to synthesize polyesters in presence of a metal triflate as a catalyst.
(4) As a cross-linking agent to enhance the mechanicalproperties and antimicrobial activities of zein films.

Safety Profile

Experimental teratogenic effects. Moderately toxic by ingestion. A severe eye irritant. Mutation data reported. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits acrid smoke and irritating fumes. See also ANHYDRIDES.

Purification Methods

Crystallise the anhydride from redistilled acetic anhydride or CHCl3, then filter, wash with diethyl ether and dry it in a vacuum. [Beilstein 17 H 606, 17 V 6.]

Succinic anhydride Preparation Products And Raw materials

Raw materials

Molybdate Maleic anhydride Phosphorus oxychloride 1,2,3,4-Tetrahydronaphthalene 1,4-Dioxane Dehydrolyzing agent Hydrogen Succinic acid Aluminum oxide

Preparation Products

Ethyl Succinyl Chloride N-Hydroxysuccinimide 4-(2-THIENYL)BUTYRIC ACID 1-PYRENEBUTYRIC ACID DICLOMEZINE 3-(4-OXO-3,5,6,7-TETRAHYDRO-4H-CYCLOPENTA[4,5]THIENO[2,3-D]PYRIMIDIN-2-YL)PROPANOIC ACID Erythromycin ethylsuccinate 3-(4-ACETYLAMINOBENZOYL)PROPANOIC ACID 3-(4-METHOXYBENZOYL)PROPIONIC ACID Fenbufen Artesunate 4-OXO-4-(2-THIENYL)BUTYRIC ACID SUCCINAMIC ACID 3-BENZOYLPROPIONIC ACID 4-(4-Methoxyphenyl)butyric acid Diethyl sebacate 3-(4-Chlorobenzoyl)propionic acid Daminozide METHYL 4-(4-(BIS(2-HYDROXYETHYL)AMINO)PHENYL)BUTYRATE Trepibutone GAMMA-CHLOROBUTYROPHENONE (4S)-HYDROXY-3-METHYL-2-(2-PROPENYL)-2-CYCLOPENTENE-1-ONE Mono-methyl succinate IMAZODAN Itaconic acid 3-(4-FLUOROBENZOYL)PROPIONIC ACID 4-(4-Aminophenyl)butyric acid Gamma Butyrolactone METHYL 4-(4-(BIS(2-CHLOROETHYL)AMINO)PHENYL)BUTYRATE
More
Less

Succinic anhydride Suppliers

Austria 3 Belgium 5 Canada 3 China 521 Europe 3 France 4 Germany 18 Hungary 1 India 46 Japan 5 Poland 1 Slovakia 1 South Korea 1 Spain 1 Switzerland 3 The Netherlands 2 United Kingdom 19 United States 88 USA 1 Global 726
Hubei Shiteng Chemical Technology Co. LTD
Tel
187-72749323 18971850150
Email
1273131441@qq.com
Country
China
ProdList
4989
Advantage
58
Handan Huajun Chemicals Co., Ltd.
Tel
0310-8166583 13303008150
Fax
+86-310-8166573
Email
884971191@qq.com
Country
China
ProdList
19
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
551-65418679 15837135945
Fax
0551-65418697
Email
info@tnjchem.com
Country
China
ProdList
1889
Advantage
62
JinJin Le Chemical Co., Ltd
Tel
10106090
Email
jjlchem2@163.com
Country
China
ProdList
9981
Advantage
58
Hubei Youyicheng Industrial Co., Ltd.
Tel
19521119694
Fax
86-027-87001826
Email
1572909019@qq.com
Country
China
ProdList
156
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2815688 13927872512
Fax
0751-8963795
Email
3007421951@qq.com
Country
China
ProdList
10057
Advantage
58
Quzhou Rundong Chemical (Technology) Co.
Tel
0570-8789886 18892685668
Fax
0570-8789985
Email
info@rundongchemical.com
Country
China
ProdList
3970
Advantage
60
ZIBO LISHUO CHEMICAL
Tel
13853320569
Email
z1184400177@163.com
Country
China
ProdList
835
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1390
Advantage
62
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
Secco work (Beijing) chemical technology co., LTD
Tel
0566-8928158
Fax
010-69755668
Email
343367102@QQ.COM
Country
China
ProdList
360
Advantage
54
Puyang Huicheng Electronic Material Co. Ltd.
Tel
0393-0393-0393-8910800 15238090375
Fax
0393-8912775
Email
info@huichengchem.com
Country
China
ProdList
557
Advantage
64
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ：3470079902
Email
675141927@qq.com
Country
China
ProdList
3203
Advantage
55
Beijing Taiya Jie Technology Development Co., Ltd.
Tel
021-33690831-8001 13552411790
Fax
021-33690831
Email
postmaster@tyjchem.cn
Country
China
ProdList
1541
Advantage
55
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2871
Advantage
58
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6134
Advantage
55
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq：2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9347
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
Shanghai Ruji Biology Technology Co., Ltd.
Tel
+86-21-65211385-8001 36031160
Fax
+86-21-65211385-8004
Email
sales@shruji.com
Country
China
ProdList
3224
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Anichem Inc.
Tel
0512-69369885
Fax
0512-69369880
Email
sales@anichem.com.cn
Country
China
ProdList
495
Advantage
55
More
Less

View Lastest Price from Succinic anhydride manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Succinic anhydride 108-30-5
Price
US $70.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-05-27
Handan Huajun chemicals Co.,Ltd
Product
Succinic anhydride 108-30-5
Price
US $2.50/kg
Min. Order
1kg
Purity
99.9% min
Supply Ability
3000mt
Release date
2024-01-17
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Succinic anhydride 108-30-5
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-07

108-30-5, Succinic anhydrideRelated Search:

2,3-Butanedione Dimethylglyoxime Trifluoromethanesulfonic anhydride Caronic anhydride Phthalic anhydride CIS-BUTENEDIOIC ANHYDRIDE Glutaric anhydride Chromium(VI) oxide Disodium succinate Polysebacic acid anhydride Succinimide Succinic acid 1,4-DIAMINOBUTANE Diphenylphosphoryl azide Dodecenylsuccinic anhydride cis-1,2,3,6-Tetrahydrophthalic anhydride Acetic anhydride Itaconic anhydride

  • 2,5(3H,4H)-Furandione
  • 5-Furandione,dihydro-2
  • bernsteinsaureanhydrid
  • Bernsteinsaure-anhydrid
  • dihydro-5-furandione
  • Dihydro-furan-2,5-dione
  • NCI-C55696
  • Oxolan-2,5-dione
  • rikacidsa
  • succinic
  • Succinyl anhydride
  • succinylanhydride
  • tetrahydro-2,5-furandione
  • AURORA KA-669
  • BUTANEDIOIC ACID ANHYDRIDE
  • BUTANEDIOIC ANHYDRIDE
  • Dihydro-2,5-diketotetrahydrofuran
  • DIHYDRO-2,5-FURANDIONE
  • AKOS BBS-00004273
  • Dihydrofuran-2,5-dione, 2,5-Dioxotetrahydrofuran
  • 2,5-FURANDIONE, DIHYDRO
  • 2,5-DIOXOTETRAHYDROFURAN
  • 2,5-DIKETOTETRAHYDROFURAN
  • SAA
  • SUCCINIC ACID ANDHYDRIDE
  • SUCCINIC ACID ANHYDRIDE
  • SUCCINYL OXIDE
  • SUCCINIC ANHYDRIDE
  • Tetrahydro-2,5-dioxofuran
  • Amyloid fibril protein AA
  • Amyloid protein A
  • SAA1
  • SAA2
  • Serum amyloid A protein
  • Human Serum Amyloid A ELISA Kit
  • Succinic anhydride >=99% (GC)
  • Succinic anhydride≥ 99% (Assay)
  • NSC 8518
  • SAN
  • Butanedioc anhydride~Dihydro-2,5-furandione
  • SUCCINIC ANHYDRIED
  • SUCCINIC ANHYDRIDE 99%
  • SUCCINIC ANHYDRIDE, 99+%
  • Succinic Acid Anhydride, 99+%
  • SuccinimideForSynthesis
  • SuccinicAnhydride,~93%
  • SuccinicAnhydrideForSynthesis
  • butanedioc anhydride
  • SUCCINICANHYDRIDE,REAGENT
  • SUCCINIC ANHYDRIDE extrapure
  • Succinic anhydride, 99% 1KG
  • Succinic anhydride, 99% 50GR
  • 3,4-Dihydro-2,5-furandione
  • 3,4-Dihydrofuran-2,5-dione
  • Tetrahydrofuran-2,5-dione
  • SAA Succinic acid anhydride
  • Bernsteinsaure anhydride
  • Succinic Anhydridc