ChemicalBook > CAS DataBase List > Methacetin

Methacetin

Product Name
Methacetin
CAS No.
51-66-1
Chemical Name
Methacetin
Synonyms
N-(4-METHOXYPHENYL)ACETAMIDE;Metacetin;METHACETIN;acetaniside;p-acetaniside;4-Acetaniside;AURORA KA-3672;Acet-p-anisidin;p-Acetanasidine;MethacetinN-(4-
CBNumber
CB6310310
Molecular Formula
C9H11NO2
Formula Weight
165.19
MOL File
51-66-1.mol
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Methacetin Property

Melting point:
128-130 °C(lit.)
Boiling point:
293.03°C (rough estimate)
Density 
1.1603 (rough estimate)
refractive index 
1.5839 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Crystalline
pka
14.53±0.70(Predicted)
color 
White
Water Solubility 
0.42 g/100 mL (20 ºC)
Merck 
14,51
BRN 
387887
Stability:
Hygroscopic
CAS DataBase Reference
51-66-1(CAS DataBase Reference)
NIST Chemistry Reference
N-(4-Methoxyphenyl)acetic acid amide(51-66-1)
EPA Substance Registry System
Acetamide, N-(4-methoxyphenyl)- (51-66-1)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/38
Safety Statements 
36-37/39-26
WGK Germany 
1
RTECS 
AE8290000
TSCA 
Yes
HS Code 
29242990
Toxicity
LD50 orl-mus: 1190 mg/kg TXAPA9 19,20,71
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
A0019
Product name
p-Acetanisidide
Purity
>98.0%(HPLC)(N)
Packaging
25g
Price
$83
Updated
2024/03/01
TCI Chemical
Product number
A0019
Product name
p-Acetanisidide
Purity
>98.0%(HPLC)(N)
Packaging
100g
Price
$203
Updated
2024/03/01
TRC
Product number
M258770
Product name
Methacetin
Packaging
500mg
Price
$80
Updated
2021/12/16
Oakwood
Product number
091550
Product name
N-(4-Methoxyphenyl)acetamide
Purity
98%
Packaging
5g
Price
$15
Updated
2021/12/16
Matrix Scientific
Product number
136397
Product name
N-(4-Methoxyphenyl)acetamide
Purity
95%+
Packaging
1g
Price
$101
Updated
2021/12/16
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Methacetin Chemical Properties,Usage,Production

Chemical Properties

LIGHT BEIGE CRYSTALLINE POWDER

Uses

Methacetin is evaluated in a breath test to predict early liver disfunction due to valproic acid and other cause. Methacetin breath test (MBT) is a rapid, non-invasive assessment of liver function in acute severe liver disease and a potential key tool in future dignosis.

Definition

ChEBI: Methacetin is a member of the class of acetamides that is paracetamol in which the hydrogen of phenolic hydroxy group has been replaced by a methyl group. It is a member of acetamides and an aromatic ether. It is functionally related to a p-anisidine and a paracetamol.

Synthesis Reference(s)

Journal of the American Chemical Society, 89, p. 7131, 1967 DOI: 10.1021/ja01002a061
The Journal of Organic Chemistry, 42, p. 3755, 1977
Organic Syntheses, Coll. Vol. 3, p. 661, 1955

Safety Profile

Moderately toxic by ingestion andother unspecified routes. When heated to decomposition itemits toxic fumes of NOx.

Methacetin Preparation Products And Raw materials

Raw materials

Preparation Products

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Methacetin Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
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View Lastest Price from Methacetin manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
Methacetin 51-66-1
Price
US $30.00-10.00/kg
Min. Order
10kg
Purity
99%
Supply Ability
100000kg
Release date
2024-08-20
Career Henan Chemical Co
Product
Methacetin 51-66-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-12

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