ChemicalBook > CAS DataBase List > Methacetin

Methacetin

Product Name
Methacetin
CAS No.
51-66-1
Chemical Name
Methacetin
Synonyms
N-(4-METHOXYPHENYL)ACETAMIDE;Metacetin;METHACETIN;acetaniside;p-acetaniside;4-Acetaniside;AURORA KA-3672;Acet-p-anisidin;p-Acetanasidine;MethacetinN-(4-
CBNumber
CB6310310
Molecular Formula
C9H11NO2
Formula Weight
165.19
MOL File
51-66-1.mol
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Methacetin Property

Melting point:
128-130 °C(lit.)
Boiling point:
293.03°C (rough estimate)
Density 
1.1603 (rough estimate)
refractive index 
1.5839 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Crystalline
pka
14.53±0.70(Predicted)
color 
White
Water Solubility 
0.42 g/100 mL (20 ºC)
Merck 
14,51
BRN 
387887
Stability:
Hygroscopic
CAS DataBase Reference
51-66-1(CAS DataBase Reference)
NIST Chemistry Reference
N-(4-Methoxyphenyl)acetic acid amide(51-66-1)
EPA Substance Registry System
Acetamide, N-(4-methoxyphenyl)- (51-66-1)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/38
Safety Statements 
36-37/39-26
WGK Germany 
1
RTECS 
AE8290000
TSCA 
Yes
HS Code 
29242990
Toxicity
LD50 orl-mus: 1190 mg/kg TXAPA9 19,20,71
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
A0019
Product name
p-Acetanisidide
Purity
>98.0%(HPLC)(N)
Packaging
25g
Price
$83
Updated
2024/03/01
TCI Chemical
Product number
A0019
Product name
p-Acetanisidide
Purity
>98.0%(HPLC)(N)
Packaging
100g
Price
$203
Updated
2024/03/01
TRC
Product number
M258770
Product name
Methacetin
Packaging
500mg
Price
$80
Updated
2021/12/16
Oakwood
Product number
091550
Product name
N-(4-Methoxyphenyl)acetamide
Purity
98%
Packaging
5g
Price
$15
Updated
2021/12/16
Matrix Scientific
Product number
136397
Product name
N-(4-Methoxyphenyl)acetamide
Purity
95%+
Packaging
1g
Price
$101
Updated
2021/12/16
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Methacetin Chemical Properties,Usage,Production

Chemical Properties

LIGHT BEIGE CRYSTALLINE POWDER

Uses

Methacetin is evaluated in a breath test to predict early liver disfunction due to valproic acid and other cause. Methacetin breath test (MBT) is a rapid, non-invasive assessment of liver function in acute severe liver disease and a potential key tool in future dignosis.

Definition

ChEBI: Methacetin is a member of the class of acetamides that is paracetamol in which the hydrogen of phenolic hydroxy group has been replaced by a methyl group. It is a member of acetamides and an aromatic ether. It is functionally related to a p-anisidine and a paracetamol.

Synthesis Reference(s)

Journal of the American Chemical Society, 89, p. 7131, 1967 DOI: 10.1021/ja01002a061
The Journal of Organic Chemistry, 42, p. 3755, 1977
Organic Syntheses, Coll. Vol. 3, p. 661, 1955

Safety Profile

Moderately toxic by ingestion andother unspecified routes. When heated to decomposition itemits toxic fumes of NOx.

Methacetin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Methacetin manufacturers

Hebei Guanlang Biotechnology Co,.LTD
Product
Methacetin 51-66-1
Price
US $30.00-10.00/kg
Min. Order
10kg
Purity
99%
Supply Ability
100000kg
Release date
2023-03-29
Career Henan Chemical Co
Product
Methacetin 51-66-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-12

51-66-1, MethacetinRelated Search:


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  • p-Acetanasidine
  • p-Acetoanisidide
  • 4'-Methoxyacetanilide, 99+%
  • n-(methoxyphenyl)acetamide
  • p-acetaniside
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  • PARA-ACETANISIDIDE
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