ChemicalBook > CAS DataBase List > 2-Amino-4-chloropyridine
2-Amino-4-chloropyridine
- Product Name
- 2-Amino-4-chloropyridine
- CAS No.
- 19798-80-2
- Chemical Name
- 2-Amino-4-chloropyridine
- Synonyms
- 4-CHLOROPYRIDIN-2-AMINE;4-chloro-2-pyridinamine;4-CHLORO-PYRIDINE-2-YLAMINE;DK765;cas:19798-80-2;IFLAB-BB F1926-0004;4-Chloropyrid-2-ylaMine;2-AMINO-4-CHLOROPYRIDINE;4-Chloro-2-aminopyridine;4-Chloro-2-amine-pyridin
- CBNumber
- CB7183078
- Molecular Formula
- C5H5ClN2
- Formula Weight
- 128.56
- MOL File
- 19798-80-2.mol
More
Less
2-Amino-4-chloropyridine Property
- Melting point:
- 126-127°C
- Boiling point:
- 240.8±20.0 °C(Predicted)
- Density
- 1.326±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO, Methanol
- pka
- 5.72±0.11(Predicted)
- form
- Liquid
- color
- Colorless to yellow to brown
- λmax
- 294nm(CHCl3)(lit.)
- Sensitive
- Air & Moisture Sensitive
- InChI
- InChI=1S/C5H5ClN2/c6-4-1-2-8-5(7)3-4/h1-3H,(H2,7,8)
- InChIKey
- RQMWVVBHJMUJNZ-UHFFFAOYSA-N
- SMILES
- C1(N)=NC=CC(Cl)=C1
- CAS DataBase Reference
- 19798-80-2(CAS DataBase Reference)
More
Less
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29333990
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 676020
- Product name
- 2-Amino-4-chloropyridine
- Purity
- 97%
- Packaging
- 5g
- Price
- $70.1
- Updated
- 2023/06/20
Sigma-Aldrich
- Product number
- 676020
- Product name
- 2-Amino-4-chloropyridine
- Purity
- 97%
- Packaging
- 25g
- Price
- $195
- Updated
- 2023/06/20
TCI Chemical
- Product number
- A2152
- Product name
- 2-Amino-4-chloropyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $71
- Updated
- 2025/07/31
TCI Chemical
- Product number
- A2152
- Product name
- 2-Amino-4-chloropyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $213
- Updated
- 2025/07/31
TRC
- Product number
- A603512
- Product name
- 2-Amino-4-chloropyridine
- Packaging
- 25g
- Price
- $140
- Updated
- 2021/12/16
More
Less
2-Amino-4-chloropyridine Chemical Properties,Usage,Production
Chemical Properties
Light yellow Cryst
Uses
2-Amino-4-chloropyridine is a useful precursor that could be used to synthesize 2-amino-4,5-dichloropyridine, 2-amino-3,4-dichloropyridine, and 2-amino-3,4,5-trichloropyridine[1].
Synthesis Reference(s)
The Journal of Organic Chemistry, 72, p. 4554, 2007 DOI: 10.1021/jo070189y
Synthesis
Methyl 4-chloropicolinate hydrochloride in methanol was treated with hydrazine hydrate, resulting in the formation of a precipitate. The suspension was then stirred for 2 hours and the precipitated hydrazide was collected through filtration. The hydrazide was dissolved in 1N hydrochloric acid and the solution was cooled to a temperature between 0-5 ℃. A solution of sodium nitrite in water was then added dropwise, causing another precipitate to form. After stirring for 15 minutes, the precipitate was collected by filtration and washed with water. The moist precipitate was then combined with a mixture of acetic acid and water, and the resulting solution was heated in a steam bath until gas evolution stopped. The reaction mixture was cooled to room temperature, the pH was adjusted to 7, and the resulting precipitate was collected via filtration. Recrystallization using ethanol yielded 2-Amino-4-chloropyridine in the form of a white crystalline solid[1].
References
[1] Gudmundsson, Kristjan S. , et al. "An Improved Large Scale Synthesis of 2-Amino-4-chloropyridine and Its Use for the Convenient Preparation of Various Polychlorinated 2-Aminopyridines." Synthetic Communications 27.5(1997):861-870.
2-Amino-4-chloropyridine Preparation Products And Raw materials
Raw materials
Hexane
Ammonium hydroxide
Hydrazinium hydroxide solution
Nitrogen
N,N-Dimethylformamide
Potassium hydroxide
Acetone
Sodium bromide
Calcium chloride
Toluene
Sodium
Hydrazine hydrate
1,4-Dioxane
Sodium nitrite
Tetrahydrofuran
Diethyl ether
Ethyl acetate
Bromine
Dichloromethane
Acetic acid
Methanol
Sodium hydroxide
2-Picolinic acid
Thionyl chloride
Sodium carbonate
Preparation Products
More
Less
2-Amino-4-chloropyridine Suppliers
- Tel
- 17316103847
- sales@deleepharma.com
- Country
- China
- ProdList
- 230
- Advantage
- 58
- Tel
- 0510-86838766 13636419861
- 2258830676@qq.com
- Country
- China
- ProdList
- 5044
- Advantage
- 58
- Tel
- 13816002113
- Fax
- -
- 68249111@qq.com
- Country
- China
- ProdList
- 70
- Advantage
- 58
- Tel
- 010-67267894 18611880885
- gianord@163.com
- Country
- China
- ProdList
- 31
- Advantage
- 58
- Tel
- 0519-89891966 13906113265
- 986329407@qq.com
- Country
- China
- ProdList
- 51
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 0514-87325867
- Fax
- 0086-514-87325867
- sales@siyuchem.com
- Country
- China
- ProdList
- 370
- Advantage
- 55
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 0418-6530555 2855550
- Fax
- +86-418-6502885
- Country
- China
- ProdList
- 338
- Advantage
- 69
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15838
- Advantage
- 69
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- sales@jonln.com
- Country
- China
- ProdList
- 1995
- Advantage
- 65
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 0311-89250318 031166536426
- Fax
- 4000311741
- master@sjzsdyn.com
- Country
- China
- ProdList
- 2806
- Advantage
- 65
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9310
- Advantage
- 66
- Tel
- 28-83379370 13880556291
- Fax
- 028-87747383
- tcy@tcypharm.com
- Country
- China
- ProdList
- 510
- Advantage
- 57
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 17702719238 18971495150;
- sales@sun-shinechem.com
- Country
- China
- ProdList
- 1077
- Advantage
- 64
- Tel
- 021-58099652-8005 13585536065
- Fax
- 021-58099609
- bin.wu@shlschem.com
- Country
- China
- ProdList
- 9883
- Advantage
- 59
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 010-59484199 18611897322
- sales@eternalchem.com
- Country
- China
- ProdList
- 4383
- Advantage
- 60
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- 86-0571-85151182
- Fax
- 86-0571-85151182
- Country
- China
- ProdList
- 5691
- Advantage
- 66
- Tel
- 028-84252981
- Fax
- +86-28-84252965
- sales@chembon.com.cn
- Country
- China
- ProdList
- 850
- Advantage
- 64
- Tel
- 86-25-57062118
- Fax
- 86-25-57065896
- sales@jspsn.com
- Country
- China
- ProdList
- 496
- Advantage
- 57
- Tel
- 0512-68780025 18962125825
- sales@ryanchem.com
- Country
- China
- ProdList
- 167
- Advantage
- 62
- Tel
- 010-81520996 13439320863
- Fax
- 010-81520996
- hengpugao@126.com
- Country
- China
- ProdList
- 159
- Advantage
- 57
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18729
- Advantage
- 57
- Tel
- +86 (21) 6435-5022
- Country
- China
- ProdList
- 4267
- Advantage
- 65
- Tel
- 400-1166-196 18981987031
- Fax
- 028-84555506 800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 11705
- Advantage
- 57
- Tel
- 0086-21-58956006
- Fax
- 0086-21-58956100
- Country
- China
- ProdList
- 7811
- Advantage
- 57
- Tel
- 400 638 7771
- sales@heowns.com
- Country
- China
- ProdList
- 14435
- Advantage
- 57
- Tel
- 86-21-63210123
- Fax
- 86-21-63290778 86-21-63218885
- sj_scrc@sinopharm.com
- Country
- China
- ProdList
- 9815
- Advantage
- 79
- Tel
- +86-25-68710855, +86-25-68710897
- Fax
- 025-68710856
- sales@springpharma.net
- Country
- China
- ProdList
- 1261
- Advantage
- 62
- Tel
- 027- 51832457 94518350
- Fax
- E-Mail Inquiry
- Country
- China
- ProdList
- 746
- Advantage
- 62
- Tel
- Please Send Email 18652950785
- Fax
- 025-87193546
- chemweiao@163.com
- Country
- China
- ProdList
- 4378
- Advantage
- 65
- Tel
- 0086-755-86198205
- acinfo@aemonchem.com
- Country
- China
- ProdList
- 1931
- Advantage
- 57
- Tel
- +86 (573) 82222445 (0)18006601000 452520369
- Fax
- +86 (573) 82222643
- sales@maya-r.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 0512-63263366 18912765016
- Fax
- 0512-6326 3366
- tongtf110@sina.com
- Country
- China
- ProdList
- 993
- Advantage
- 62
- Tel
- +86 (21) 5196-9732
- Fax
- +86 (21) 5196-9733
- Country
- China
- ProdList
- 996
- Advantage
- 57
- Tel
- 021-56491756 13512199871
- Fax
- 021-5649-1756
- 2819742715@qq.com
- Country
- China
- ProdList
- 4000
- Advantage
- 55
- Tel
- 022-58013646 13011382049
- Fax
- 022-23854368
- sales@jinyudachem.com
- Country
- China
- ProdList
- 1930
- Advantage
- 55
- Tel
- +21-18501659228 18501659228
- Fax
- sales@hope-chem.com
- info@hope-chem.com
- Country
- China
- ProdList
- 474
- Advantage
- 55
- Tel
- 18030648795
- Fax
- 028-61777050
- sales@cdforestchem.com
- Country
- China
- ProdList
- 1999
- Advantage
- 58
- Tel
- 0755-4000505016 13380397412
- Fax
- 0755 28094224
- 3001272453@qq.com
- Country
- China
- ProdList
- 5158
- Advantage
- 50
More
Less
View Lastest Price from 2-Amino-4-chloropyridine manufacturers
Changzhou waston chemical technology Co.,Ltd
- Product
- 2-Amino-4-chloropyridine 19798-80-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- As your request
- Release date
- 2025-11-04
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- 2-Amino-4-chloropyridine 19798-80-2
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 500KGS
- Release date
- 2021-06-19
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- 2-Amino-4-chloropyridine 19798-80-2
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-07
19798-80-2, 2-Amino-4-chloropyridineRelated Search:
ALTRENOGEST
Pentachloropyridine
3-Aminophenol
2-Chloro-3-hydroxypyridine
4-Dimethylaminopyridine
6-Aminocaproic acid
3-Aminopyridine
Glycine
2-Aminopyridine
Clopidol
N-(5-Chloropyridin-2-yl)oxalaMic acid ethyl ester
Oxalic acid 1-ethyl ester
Tris(hydroxymethyl)aminomethane
2-AMINO-3-CHLOROPYRIDINE
6-AMINO-2-CHLOROPYRIDINE,2-AMINO-6-CHLOROPYRIDINE (6-CHLOROPYRIDIN-2-YLAMINE)
2-Amino-5-chloropyridine
Edoxaban Impurity 12 (1R,2R,4S)
tert-butyl (1R,2S,5S)-2-aMino-5-(diMethylcarbaMoyl)cyclohexylcarbaMate