Ethyl 4-piperidinecarboxylate

Product Name: Ethyl 4-piperidinecarboxylate
CAS No.: 1126-09-6
Chemical Name: Ethyl 4-piperidinecarboxylate
Synonyms: ETHYL PIPERIDINE-4-CARBOXYLATE;ETHYL ISONIPECOTATE;4-piperidinecarboxylate;PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER;H-Nip-OEt;H-DL-Inp-OEt;AKOS MSC-0737;RARECHEM AH CK 0180;TIMTEC-BB SBB004006;ETHYL ISONEPECOTATE
CBNumber: CB7231962
Molecular Formula: C8H15NO2
Formula Weight: 157.21
MOL File: 1126-09-6.mol

More

Less

Ethyl 4-piperidinecarboxylate Property

Boiling point:: 204 °C(lit.)
Density: 1.02 g/mL at 25 °C(lit.)
vapor pressure: 39.4Pa at 25℃
refractive index: n20/D 1.459(lit.)
Flash point:: 176 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: Liquid
pka: 9.83±0.10(Predicted)
color: Clear colorless to slightly brown
Water Solubility: miscible
BRN: 118419
LogP: 1.15
CAS DataBase Reference: 1126-09-6(CAS DataBase Reference)
NIST Chemistry Reference: Ethyl piperidine-4-carboxylate(1126-09-6)

More

Less

Safety

Hazard Codes: C,Xi
Risk Statements: 34-36/37/38
Safety Statements: 23-24/25-36-26
RIDADR: UN2735
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29333999

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E33505
Product name: Ethyl isonipecotate
Purity: 98%
Packaging: 25g
Price: $51.3
Updated: 2024/03/01

Sigma-Aldrich

Product number: E33505
Product name: Ethyl isonipecotate
Purity: 98%
Packaging: 100g
Price: $148
Updated: 2024/03/01

TCI Chemical

Product number: I0294
Product name: Ethyl 4-Piperidinecarboxylate
Purity: >98.0%(GC)
Packaging: 25mL
Price: $36
Updated: 2024/03/01

TCI Chemical

Product number: I0294
Product name: Ethyl 4-Piperidinecarboxylate
Purity: >98.0%(GC)
Packaging: 100mL
Price: $94
Updated: 2024/03/01

Alfa Aesar

Product number: B20601
Product name: Ethyl isonipecotate, 98%
Packaging: 25g
Price: $40.65
Updated: 2024/03/01

More

Less

Ethyl 4-piperidinecarboxylate Chemical Properties,Usage,Production

Chemical Properties

clear colorless to slightly brown liquid

Uses

Reactant for synthesis of:• ;SMN protein modulators1• ;β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition2• ;Nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone3• ;RhoA inhibitors for cardiovascular disease therapy4• ;Saccharin derived Mannich bases as antimicrobials and antioxidants5Reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates6

Uses

Reactant for synthesis of SMN protein modulators and β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition.

Uses

It is used as a reactant for synthesis of SMN protein modulators, β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition, nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone. It is also involved in the reactions of RhoA inhibitors for cardiovascular disease therapy and saccharin derived Mannich bases as antimicrobials and antioxidants. It is employed as a reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates.

Synthesis Reference(s)

Tetrahedron Letters, 23, p. 193, 1982 DOI: 10.1016/S0040-4039(00)86783-0

Ethyl 4-piperidinecarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

1-BOC-4-ETHYL-4-PIPERIDINECARBOXYLIC ACID ETHYL 1-(2-CHLOROACETYL)-4-PIPERIDINECARBOXYLATE (R)-3-Aminoquinuclidine dihydrochloride Ethyl 2-(4-(ethoxycarbonyl)piperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate (R)-(-)-3-Quinuclidinol 1-(2,6-DIMETHOXYBENZYL)PIPERIDIN-4-AMINE HYDROCHLORIDE 1-(PYRIMIDIN-2-YL)PIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE 4-ALLYL-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-TERT-BUTYL ESTER 1-Boc-4-methylpiperidine-4-carboxylic acid 3-Quinuclidinone hydrochloride (S)-(+)-3-Quinuclidinol Ethyl N-Boc-4-methylpiperidine-4-carboxylate (S)-3-Aminoquinuclidine dihydrochloride 3-Aminoquinuclidine dihydrochloride 1-(PYRIMIDIN-2-YL)PIPERIDINE-3-CARBOHYDRAZIDE Ethyl 2-(4-(ethoxycarbonyl)piperidin-1-yl)pyrimidine-5-carboxylate quinuclidine-3-carboxylic acid (R)-3-Quinuclidinol hydrochloride

More

Less

Ethyl 4-piperidinecarboxylate Suppliers

Americas 1 Belgium 4 Canada 1 China 374 Europe 4 France 5 Germany 16 India 59 Ireland 1 Italy 1 Japan 7 Singapore 1 Slovakia 1 South Korea 3 Switzerland 4 Ukraine 2 United Kingdom 23 United States 60 Global 567

CMS Chemicals Limited

Tel: --
Fax: --
Email: cms.marketing@cms-chemicals.com
Country: United Kingdom
ProdList: 3708
Advantage: 60

Biokemix

Tel: --
Fax: --
Email: info@biokemix.com
Country: United Kingdom
ProdList: 1066
Advantage: 58

Cenik Chemicals

Tel: --
Fax: --
Email: lo@cenikchemicals.com
Country: United Kingdom
ProdList: 1681
Advantage: 58

Molekula Limited

Tel: --
Fax: --
Email: o@molekula.com
Country: United Kingdom
ProdList: 6127
Advantage: 58

LEHVOSS UK / Gee Lawson Chemical Division

Tel: --
Fax: --
Email: david.davies@lehvoss.co.uk
Country: United Kingdom
ProdList: 892
Advantage: 58

Apollo Scientific Ltd

Tel: --
Fax: --
Email: ales@apo
Country: United Kingdom
ProdList: 4521
Advantage: 58

Melrob Ltd (part of Nordmann)

Tel: --
Fax: --
Email: nquiries@melrob.com
Country: United Kingdom
ProdList: 3065
Advantage: 58

Apollo Scientific Ltd.

Tel: --
Fax: --
Email: sales@apolloscientific.co.uk
Country: United Kingdom
ProdList: 6084
Advantage: 88

Apin Chemicals Limited (UK)

Tel: --
Fax: --
Email: info@apinchemicals.com
Country: United Kingdom
ProdList: 6184
Advantage: 60

Carbosynth Limited

Tel: --
Fax: --
Email: sales@carbosynth.com
Country: United Kingdom
ProdList: 6581
Advantage: 61

Leancare Ltd.

Tel: --
Fax: --
Email: enquiry@leancare.co.uk
Country: United Kingdom
ProdList: 6446
Advantage: 42

Manchester Organics

Tel: --
Fax: --
Email: info@manchesterorganics.com
Country: United Kingdom
ProdList: 6834
Advantage: 67

CARBONE SCIENTIFIC CO.,LTD

Tel: --
Fax: --
Email: sales@carbonesci.com
Country: United Kingdom
ProdList: 6666
Advantage: 30

MOLEKULA Ltd.

Tel: --
Fax: --
Email: kevinbanks@molekula.com
Country: United Kingdom
ProdList: 6140
Advantage: 66

ETA SCIENTIFIC Co.,Ltd

Tel: --
Fax: --
Email: sales@etascientific.com
Country: United Kingdom
ProdList: 6090
Advantage: 34

UK GREEN SCIENTIFIC CO.,LIMITED

Tel: --
Fax: --
Email: sales@gs-chem.com
Country: United Kingdom
ProdList: 6098
Advantage: 47

Fluorochem Ltd

Tel: --
Fax: --
Email: vernam@fluorochem.co.uk
Country: United Kingdom
ProdList: 6375
Advantage: 65

Eurolabs Limited

Tel: --
Fax: --
Country: United Kingdom
ProdList: 6309
Advantage: 46

Fulcrum Scientific Ltd.

Tel: --
Fax: --
Country: United Kingdom
ProdList: 6565
Advantage: 38

Fluorochem Ltd.

Tel: --
Fax: --
Email: enquiries@fluorochem.co.uk
Country: United Kingdom
ProdList: 6401
Advantage: 74

Apin Chemicals Ltd.

Tel: --
Fax: --
Email: info@apinchemicals.com
Country: United Kingdom
ProdList: 6807
Advantage: 42

VWR International

Tel: --
Fax: --
Email: solutions@vwr.com
Country: United Kingdom
ProdList: 6548
Advantage: 82

Zerenex Molecular Limited

Tel: --
Fax: --
Email: sales@zerenex-molecular.com
Country: United Kingdom
ProdList: 6204
Advantage: 47

More

Less

View Lastest Price from Ethyl 4-piperidinecarboxylate manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Ethyl 4-piperidinecarboxylate 1126-09-6
Price: US $0.10/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10
Release date: 2024-07-14

Hebei Kingfiner Technology Development Co.Ltd

Product: Ethyl piperidine-4-carboxylate 1126-09-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500000kg
Release date: 2023-12-21

Anhui Yiao New Material Technology Co., Ltd

Product: Ethyl 4-piperidinecarboxylate 1126-09-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1 ton
Release date: 2023-11-02

1126-09-6, Ethyl 4-piperidinecarboxylateRelated Search:

ETHYL 4-PIPERIDINECARBOXYLATE HYDROCHLORIDE,ETHYL 4-PIPERIDINECARBOXYLATE HCL Ethyl nipecotate hydrochloride(Ethyl 3-Piperidinecarboxylate hydrochloride) Isonipecotic acid 1-PIPERIDINECARBONYL CHLORIDE 4-PIPERIDINECARBOXYLIC ACID T-BUTYL ESTER HCL Hexahydroisonicotinamide Methyl 4-piperidinecarboxylate 4-Piperidinemethanol 4,4-Piperidinediol hydrochloride 1-BENZYL-3-OXO-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER MEPERIDINE Ethyl 1-methyl-4-piperidinecarboxylate ETHYL 1-(2-CHLOROACETYL)-4-PIPERIDINECARBOXYLATE Ethyl 4-piperidinecarboxylate DIPHENOXYLATE HYDROCHLORIDE MEPERIDINE HYDROCHLORIDE Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate Ethyl N-benzyl-3-oxo-4-piperidine-carboxylate hydrochloride

4-Carbethoxypiperidine

ISONIPECOTINIC ACID ETHYL ESTER

Ethyl isonipecotate ,97%

1-ethylpiperidine-4-carboxylate

ethyl piperidin-4-carboxylate

Ethyl isonipecotate, 98+% 100GR

Ethyl isonipecotate, 98+% 25GR

Ethyl Isonipecotate Isonipecotic Acid Ethyl Ester 4-Piperidinecarboxylic Acid Ethyl Ester

Ethyl isonipecotate, 4-(Ethoxycarbonyl)piperidine

4-piperidine forMic acid ethyl ester

Ethyl isonipecotate 98%

Ethyl 4-Piperidinecarboxylate, 97.0%

4 - piperidine ethyl forMate

Ethyl 4-piperidinecarboxylate for synthesis

Ethyl 4-piperidinecarboxylate ESTER

4-piperidinecarboxylate

4-Carboethoxypiperidine

ISONIPECOTIC ACID ETHYL ESTER

ETHYL ISONIPECOTATE

ETHYL PIPERIDINE-4-CARBOXYLATE

ETHYL 4-PIPERIDINECARBOXYLATE

LABOTEST-BB LT00159543

4-PIPERDINECARBOXYLIC ACID, ETHYL ESTER

4-PIPERIDINECARBOXYLIC ACID ETHYL ESTER

AKOS MSC-0737

RARECHEM AH CK 0180

PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER

TIMTEC-BB SBB004006

Ethyl Isonipecotate(ethyl 4-Piperidinecarboxylate)

Hexahydroisonicotinic acid, ethyl ester

Ethyl isonipecotate, 98+%

Ethyl piperidine-4-carboxylate 97%

Ethyl 4-Piperidinecarboxylate (Ethyl isonipecotate)

H-DL-Inp-OEt

H-Nip-OEt

PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER, ISONIPECOTINIC ACID ETHYL ESTER

Isopecoticacidethylester

Piperidin-4-carboxylic acid ethyl ester

4-(Ethoxycarbonyl)piperidine

Ethyl piperidine-4-carboxylate ,97%

Isonipecotic acid ethyl

Piperidine-4-carboxylic acid ethyl

Ethyl isonipcotinate

Ethyl4-Piperidinecarboxylate&gt

Avatrombopag Impurity 11

ETHYL ISONEPECOTATE

Ethyl isohipecotate

Piperidine-4-carboxylate, ethyl ester

1-(1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carbonyl) piperidine-4-carboxylic acid

Avatroposide impurities17

Avatrapa impurity 11

4-Piperidinecarboxylic Acid Ethyl Ester (Ethyl isonipecotate)

Ethyl 4-piperoxyformate

Impurity 15 of pentaethyl quinone hydrochloride

1126-09-6

1123-09-6

Heterocyclic Building Blocks

Piperidines