2-Amino-5-bromopyridine

Product Name: 2-Amino-5-bromopyridine
CAS No.: 1072-97-5
Chemical Name: 2-Amino-5-bromopyridine
Synonyms: 5-BROMOPYRIDIN-2-AMINE;5-BROMOPHTHALIDE;5-bromo-2-pyridylamine;5-BROMO-PYRIDIN-2-YLAMINE;NSC 26282;JACS-1072-97-5;AKOS BBS-00004444;TIMTEC-BB SBB003823;2-Amino-5-bromopyrid;5-Brom-2-pyridylamin
CBNumber: CB7403950
Molecular Formula: C5H5BrN2
Formula Weight: 173.01
MOL File: 1072-97-5.mol

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2-Amino-5-bromopyridine Property

Melting point:: 133-138 °C (lit.)
Boiling point:: 230.9±20.0 °C(Predicted)
Density: 1.6065 (rough estimate)
refractive index: 1.5182 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 4.65±0.13(Predicted)
form: Crystalline Powder
color: White to beige
Water Solubility: Soluble in methanol, chloroform, ethyl acetate. Slightly soluble in water.
BRN: 108737
InChI: InChI=1S/C5H5BrN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)
InChIKey: WGOLHUGPTDEKCF-UHFFFAOYSA-N
SMILES: C1(N)=NC=C(Br)C=C1
CAS DataBase Reference: 1072-97-5(CAS DataBase Reference)
EPA Substance Registry System: 2-Amino-5-bromopyridine (1072-97-5)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38
Safety Statements: 26-36
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 2
F: 10
HazardClass: IRRITANT
HS Code: 29333999

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 122858
Product name: 2-Amino-5-bromopyridine
Purity: 97%
Packaging: 5g
Price: $58.9
Updated: 2025/07/31

Sigma-Aldrich

Product number: 122858
Product name: 2-Amino-5-bromopyridine
Purity: 97%
Packaging: 25g
Price: $85.8
Updated: 2025/07/31

TCI Chemical

Product number: A1587
Product name: 2-Amino-5-bromopyridine
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $20
Updated: 2025/07/31

TCI Chemical

Product number: A1587
Product name: 2-Amino-5-bromopyridine
Purity: >98.0%(GC)(T)
Packaging: 250g
Price: $143
Updated: 2025/07/31

TRC

Product number: A601871
Product name: 2-Amino-5-bromopyridine
Packaging: 5g
Price: $140
Updated: 2021/12/16

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2-Amino-5-bromopyridine Chemical Properties,Usage,Production

Chemical Properties

Light yellow Cryst

Uses

2-Amino-5-bromopyridine is used for the synthesis of polycyclic azaarenes.

General Description

2-Amino-5-bromopyridine is a brominated aromatic amine reagent and is used for labeling of model reducing-end oligosaccharides via reductive amination.

Synthesis

39856-50-3

1072-97-5

General procedure for the synthesis of 2-amino-5-bromopyridine from 5-bromo-2-nitropyridine: 5-bromo-2-nitropyridine (0.6 mmol), 5 wt% Pd/C (0.5 mol%, 0.003 mmol), H2O (10 equiv, 6.0 mmol), B2(OH)4 (3.3 equiv, 2.0 mmol) and CH3CN ( 1.0 mL) were added to a 10 mL reaction tube. The reaction mixture was stirred at 50 °C for 24 hours. The progress of the reaction was monitored by TLC and when the reaction was complete, the mixture was cooled to room temperature. Water (5 mL) was added and extracted with EtOAc (3 x 5 mL). The organic phases were combined, dried with anhydrous Na2SO4, filtered and concentrated under reduced pressure. The residue was purified by silica gel column chromatography to afford the target product 2-amino-5-bromopyridine (55 mg, 99% yield).

References

[1] Tetrahedron, 2017, vol. 73, # 27-28, p. 3898 - 3904
[2] Organic Process Research and Development, 2017, vol. 21, # 2, p. 247 - 252
[3] Organic Letters, 2016, vol. 18, # 11, p. 2774 - 2776
[4] ACS Catalysis, 2015, vol. 5, # 3, p. 1526 - 1529
[5] Yakugaku Zasshi, 1952, vol. 72, p. 381

2-Amino-5-bromopyridine Preparation Products And Raw materials

Raw materials

Preparation Products

2-Fluoropyridine-5-carboxaldehyde 5-Bromo-2-fluoropyridine N-(5-BROMO-3-NITROPYRIDIN-2-YL)ACETAMIDE 2-Fluoropyridine-5-boronic acid 5-Fluoro-6-methoxypyridine-3-boronic acid 4-bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine 2-Hydroxy-5-bromopyridine 3-AMINO-5-BROMO-PYRIDIN-2-OL 2-Amino-5-bromo-3-nitropyridine 2-amino-5-bromopyridin-3-ol 2-Amino-5-cyanopyridine 5-Bromo-2-chloro-3-nitropyridine 5-Bromo-3-nitro-2-pyridinol

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2-Amino-5-bromopyridine Suppliers

Americas 1 Belgium 2 Canada 6 China 609 Europe 4 France 3 Germany 13 Hungary 1 India 108 Japan 5 Jordan 1 Poland 2 Slovakia 1 South Korea 5 Switzerland 2 Ukraine 2 United Kingdom 22 United States 64 Global 851

Alkemi BVBA

Tel: --
Fax: --
Email: nfo@alkemi.be
Country: Belgium
ProdList: 2201
Advantage: 58

Acros Organics

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Email: info@acros.com
Country: Belgium
ProdList: 6772
Advantage: 81

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View Lastest Price from 2-Amino-5-bromopyridine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Amino-5-bromopyridine 1072-97-5
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-29

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Amino-5-bromopyridine 1072-97-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-12

R&D Scientific Inc.

Product: 2-Amino-5-bromopyridine 1072-97-5
Price: US $780.00/Kg
Min. Order: 1Kg
Purity: 98
Supply Ability: 5000 Kg
Release date: 2025-03-28

1072-97-5, 2-Amino-5-bromopyridineRelated Search:

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2-AMINO-5-BROMOPYRIDINE

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5-BROMO-2-AMINOPYRIDINE

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TIMTEC-BB SBB003823

LABOTEST-BB LT00129606

Palbociclib impurityB

2 - aMino - 5 - broMide pyridine

2-Amino-5-bromopyridine Synonyms 5-Bromopyridin-2-amine

Pyridine, 2-amino-5-bromo-

2-Amino-5-brompyridine for synthesis

Pabuxirib starting material 2 Impurity E (2-amino-5-bromopyridine)

JACS-1072-97-5

5-BROMOPHTHALIDE

2-AMINO-5-BROMOPYRIDINE 98%

2-AMINO-5-BROMOPYRIDINE 5-BROMOPYRIDIN-2-YLAMINE

2-Amino-5-bromopyridine ,98%

2-Amino-5-bromopyridine,97%

2 - amino - 5 - bromine pyridine

2-Amino-5-bromopyrid

5-Bromo-2-pyridinamine

NSC 26282

5-broMo-2-aMinopyridin

2-AMino-5-broMopyridine, 97% 5GR

2--5- aMinopyridinebroMide

Palbociclib Impurity 59

2-Amino-5-bromopyridine &gt

2-Pyridinamine, 5-bromo-

2-Amino-5-bromopyridine ISO 9001：2015 REACH

5-Brom-2-pyridylamin

2-Amino-5-bromopyridine, 95%

6-bromo-8-cyclopentyl-5-methyl-2-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one

tert-butyl4-(6-((2-(cyclopentylamino)pyrimidin-4-yl)amino)pyri- din-3-yl) piperazine-1-carboxylate

1072-97-5

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20511-21-0

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C5H5BrN2MW17301

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