ChemicalBook > CAS DataBase List > 2-Amino-5-bromopyridine

2-Amino-5-bromopyridine

Product Name
2-Amino-5-bromopyridine
CAS No.
1072-97-5
Chemical Name
2-Amino-5-bromopyridine
Synonyms
5-BROMOPYRIDIN-2-AMINE;5-BROMOPHTHALIDE;5-bromo-2-pyridylamine;5-BROMO-PYRIDIN-2-YLAMINE;NSC 26282;JACS-1072-97-5;AKOS BBS-00004444;TIMTEC-BB SBB003823;2-Amino-5-bromopyrid;5-Brom-2-pyridylamin
CBNumber
CB7403950
Molecular Formula
C5H5BrN2
Formula Weight
173.01
MOL File
1072-97-5.mol
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2-Amino-5-bromopyridine Property

Melting point:
133-138 °C (lit.)
Boiling point:
230.9±20.0 °C(Predicted)
Density 
1.6065 (rough estimate)
refractive index 
1.5182 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
4.65±0.13(Predicted)
form 
Crystalline Powder
color 
White to beige
Water Solubility 
Soluble in methanol, chloroform, ethyl acetate. Slightly soluble in water.
BRN 
108737
InChI
InChI=1S/C5H5BrN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)
InChIKey
WGOLHUGPTDEKCF-UHFFFAOYSA-N
SMILES
C1(N)=NC=C(Br)C=C1
CAS DataBase Reference
1072-97-5(CAS DataBase Reference)
EPA Substance Registry System
2-Amino-5-bromopyridine (1072-97-5)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26-36
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
2
F 
10
HazardClass 
IRRITANT
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
122858
Product name
2-Amino-5-bromopyridine
Purity
97%
Packaging
5g
Price
$58.9
Updated
2025/07/31
Sigma-Aldrich
Product number
122858
Product name
2-Amino-5-bromopyridine
Purity
97%
Packaging
25g
Price
$85.8
Updated
2025/07/31
TCI Chemical
Product number
A1587
Product name
2-Amino-5-bromopyridine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$20
Updated
2025/07/31
TCI Chemical
Product number
A1587
Product name
2-Amino-5-bromopyridine
Purity
>98.0%(GC)(T)
Packaging
250g
Price
$143
Updated
2025/07/31
TRC
Product number
A601871
Product name
2-Amino-5-bromopyridine
Packaging
5g
Price
$140
Updated
2021/12/16
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2-Amino-5-bromopyridine Chemical Properties,Usage,Production

Chemical Properties

Light yellow Cryst

Uses

2-Amino-5-bromopyridine is used for the synthesis of polycyclic azaarenes.

General Description

2-Amino-5-bromopyridine is a brominated aromatic amine reagent and is used for labeling of model reducing-end oligosaccharides via reductive amination.

Synthesis

39856-50-3

1072-97-5

General procedure for the synthesis of 2-amino-5-bromopyridine from 5-bromo-2-nitropyridine: 5-bromo-2-nitropyridine (0.6 mmol), 5 wt% Pd/C (0.5 mol%, 0.003 mmol), H2O (10 equiv, 6.0 mmol), B2(OH)4 (3.3 equiv, 2.0 mmol) and CH3CN ( 1.0 mL) were added to a 10 mL reaction tube. The reaction mixture was stirred at 50 °C for 24 hours. The progress of the reaction was monitored by TLC and when the reaction was complete, the mixture was cooled to room temperature. Water (5 mL) was added and extracted with EtOAc (3 x 5 mL). The organic phases were combined, dried with anhydrous Na2SO4, filtered and concentrated under reduced pressure. The residue was purified by silica gel column chromatography to afford the target product 2-amino-5-bromopyridine (55 mg, 99% yield).

References

[1] Tetrahedron, 2017, vol. 73, # 27-28, p. 3898 - 3904
[2] Organic Process Research and Development, 2017, vol. 21, # 2, p. 247 - 252
[3] Organic Letters, 2016, vol. 18, # 11, p. 2774 - 2776
[4] ACS Catalysis, 2015, vol. 5, # 3, p. 1526 - 1529
[5] Yakugaku Zasshi, 1952, vol. 72, p. 381

2-Amino-5-bromopyridine Preparation Products And Raw materials

Raw materials

Preparation Products

2-Fluoropyridine-5-carboxaldehyde 5-Bromo-2-fluoropyridine N-(5-BROMO-3-NITROPYRIDIN-2-YL)ACETAMIDE 2-Fluoropyridine-5-boronic acid 5-Fluoro-6-methoxypyridine-3-boronic acid 4-bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine 2-Hydroxy-5-bromopyridine 3-AMINO-5-BROMO-PYRIDIN-2-OL 2-Amino-5-bromo-3-nitropyridine 2-amino-5-bromopyridin-3-ol 2-Amino-5-cyanopyridine 5-Bromo-2-chloro-3-nitropyridine 5-Bromo-3-nitro-2-pyridinol
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2-Amino-5-bromopyridine Suppliers

Americas 1 Belgium 2 Canada 6 China 610 Europe 4 France 3 Germany 13 Hungary 1 India 108 Japan 5 Jordan 1 Poland 2 Slovakia 1 South Korea 5 Switzerland 2 Ukraine 2 United Kingdom 22 United States 64 Global 852
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View Lastest Price from 2-Amino-5-bromopyridine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Amino-5-bromopyridine 1072-97-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-29
Henan Aochuang Chemical Co.,Ltd.
Product
2-Amino-5-bromopyridine 1072-97-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-12
R&D Scientific Inc.
Product
2-Amino-5-bromopyridine 1072-97-5
Price
US $780.00/Kg
Min. Order
1Kg
Purity
98
Supply Ability
5000 Kg
Release date
2025-03-28

1072-97-5, 2-Amino-5-bromopyridineRelated Search:

2-Chloro-3-cyanopyridine Triethanolamine 4-Dimethylaminopyridine N-Ethylmethylamine Glycine Triethylamine Bis(2-ethylhexyl)amine 2-Aminopyridine Dibenzylamine 1-Hexadecylpyridinium bromide ALTRENOGEST 3-Aminopyridine 6-Aminocaproic acid 2-Aminophenol Tris(hydroxymethyl)aminomethane 3-AMINO-5-BROMOPYRIDINE 2-(5-BROMO-2-PYRIDYLAZO)-5-(DIETHYLAMINO)PHENOL 2-Amino-5-bromo-3-methylpyridine

  • 2-AMINO-5-BROMOPYRIDINE
  • AKOS BBS-00004444
  • 5-BROMO-PYRIDIN-2-YLAMINE
  • 5-BROMOPYRIDIN-2-AMINE
  • 5-BROMO-2-AMINOPYRIDINE
  • 5-bromo-2-pyridylamine
  • 2-AMINO-5-BROMOPYRDIDINE
  • AMINO-5-BROMOPYRIDINE
  • TIMTEC-BB SBB003823
  • LABOTEST-BB LT00129606
  • Palbociclib impurityB
  • 2 - aMino - 5 - broMide pyridine
  • 2-Amino-5-bromopyridine Synonyms 5-Bromopyridin-2-amine
  • Pyridine, 2-amino-5-bromo-
  • 2-Amino-5-brompyridine for synthesis
  • Pabuxirib starting material 2 Impurity E (2-amino-5-bromopyridine)
  • JACS-1072-97-5
  • 5-BROMOPHTHALIDE
  • 2-AMINO-5-BROMOPYRIDINE 98%
  • 2-AMINO-5-BROMOPYRIDINE 5-BROMOPYRIDIN-2-YLAMINE
  • 2-Amino-5-bromopyridine ,98%
  • 2-Amino-5-bromopyridine,97%
  • 2 - amino - 5 - bromine pyridine
  • 2-Amino-5-bromopyrid
  • 5-Bromo-2-pyridinamine
  • NSC 26282
  • 5-broMo-2-aMinopyridin
  • 2-AMino-5-broMopyridine, 97% 5GR
  • 2--5- aMinopyridinebroMide
  • Palbociclib Impurity 59
  • 2-Amino-5-bromopyridine &gt
  • 2-Pyridinamine, 5-bromo-
  • 2-Amino-5-bromopyridine ISO 9001：2015 REACH
  • 5-Brom-2-pyridylamin
  • 2-Amino-5-bromopyridine, 95%
  • 6-bromo-8-cyclopentyl-5-methyl-2-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
  • tert-butyl4-(6-((2-(cyclopentylamino)pyrimidin-4-yl)amino)pyri- din-3-yl) piperazine-1-carboxylate
  • 1072-97-5
  • 1072-95-5
  • 20511-21-0
  • 1072-97-57
  • 6345-47-9
  • C5H5BrN2MW17301
  • C5H6BrN2
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  • Bromopyridines
  • Pyridines
  • Pyrimidines
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