3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Product Name: 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS No.: 151266-23-8
Chemical Name: 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Synonyms: 4-Amino-3-iodopyrazolo[3,4-d]pyrimidine;IbrutinibIntermediate6;7-Iodo-7-deaza-8-aza-adenine;4-AMINO-3-IODO-1H-PYRAZOLO[3;4-AMino-3-iodopyrazolo[3,4-d]pyridine;3-iodo-4-Aminopyrazolo[3,4-d]pyridine;3-iodopyrazolo[3,4-d]pyriMidin-4-aMine;3-iodo-4-AMino-1H-pyrazolo[3,4-d]pyridine;4-Amino-3-iodo-1H-pyrazolo[3,4-D]pyridine;3-iodo-2H-pyrazolo[3,4-d]pyrimidin-4-amine
CBNumber: CB8144555
Molecular Formula: C5H4IN5
Formula Weight: 261.02
MOL File: 151266-23-8.mol

More

Less

3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine Property

Boiling point:: 312.3±52.0 °C(Predicted)
Density: 2.92±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: powder to crystal
pka: 10.50±0.20(Predicted)
color: White to Light yellow to Light orange
Sensitive: Light Sensitive
λmax: 282nm(lit.)
InChI: InChI=1S/C5H4IN5/c6-3-2-4(7)8-1-9-5(2)11-10-3/h1H,(H3,7,8,9,10,11)
InChIKey: HQAIUXZORKJOJY-UHFFFAOYSA-N
SMILES: C1=NC(N)=C2C(I)=NNC2=N1

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36/37/39-37
TSCA: N
HS Code: 29335990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: I0941
Product name: 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $61
Updated: 2024/03/01

TCI Chemical

Product number: I0941
Product name: 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $300
Updated: 2024/03/01

Alfa Aesar

Product number: H52572
Product name: 4-Amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine, 97%
Packaging: 250mg
Price: $144
Updated: 2021/12/16

TRC

Product number: I736005
Product name: 3-Iodo-3H-pyrazolo[3,4-d]pyrimidin-4-amine
Packaging: 1g
Price: $105
Updated: 2021/12/16

TRC

Product number: I736005
Product name: 3-Iodo-3H-pyrazolo[3,4-d]pyrimidin-4-amine
Packaging: 25g
Price: $1765
Updated: 2021/12/16

More

Less

3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine Chemical Properties,Usage,Production

Uses

3-Iodo-3H-pyrazolo[3,4-d]pyrimidin-4-amine acts as a reagent in the discovery and preparation of CHMFL-FLT3-122 as potent and orally available FLT3 kinase inhibitor for FLT3-ITD positive acute myeloid leukemia. Development and preparation of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes.

Synthesis

A solution of 3H-pyrazolo[3,4-d]pyrimidin-4-amine (10 g, 0.074 mol) and n-iodo-succinamide (25 g, 0.111 mol) in DMF (80 mL) was heated to 80° C. overnight under an argon atmosphere. The resulting solid was filtered and rinsed with cold EtOH. The product was dried in vacuo overnight to yield 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (24 g, 100 per cent yield).

3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine Suppliers

Americas 1 Belgium 1 Canada 1 China 285 Europe 1 France 1 Germany 6 India 16 Japan 1 Switzerland 1 The Netherlands 1 United Kingdom 9 United States 40 Global 364

Ark Pharm, Inc.

Tel: 847-367-3680
Fax: 847-367-3681
Email: sales@arkpharminc.com
Country: United States
ProdList: 1670
Advantage: 56

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Accela ChemBio Inc.

Tel: +1(858) 699-3322
Fax: +1(858) 876-1948
Email: marketing@accelachem.com
Country: United States
ProdList: 6024
Advantage: 65

AbaChemScene

Tel: 732-484-9848
Fax: 888-484-5008
Email: sales@chemscene.com
Country: United States
ProdList: 3982
Advantage: 60

Accela ChemBio Inc.

Tel: +1-858-6993322
Fax: (+1)-858-876-1948
Email: info@accelachem.com
Country: United States
ProdList: 18478
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Protheragen-ING

Tel: +16313385890
Email: info@protheragen-ing.com
Country: United States
ProdList: 3868
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Alfa Chemistry

Tel
Email: info@alfa-chemistry.com
Country: United States
ProdList: 2344
Advantage: 58

Aston Chemical

Tel: 13000000000
Email: sales@astonchem.com
Country: United States
ProdList: 1634
Advantage: 58

Synthonix Inc

Tel: --
Fax: --
Email: info@synthonix.com
Country: United States
ProdList: 6872
Advantage: 58

Sphinx Scientific Laboratory, LLC

Tel: --
Fax: --
Email: sales@sphinxscientificlab.com
Country: United States
ProdList: 3343
Advantage: 50

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

Fluorochem Ltd.

Tel: --
Fax: --
Email: enquiries@fluorochem.co.uk
Country: United States
ProdList: 4583
Advantage: 58

eNovation Chemicals LLC

Tel: --
Fax: --
Email: ales@eNovationChem.com
Country: United States
ProdList: 1673
Advantage: 58

Alichem Inc.

Tel: --
Fax: --
Email: sales@alichem.com
Country: United States
ProdList: 6167
Advantage: 58

AstaTech, Inc.

Tel: --
Fax: --
Email: sales@astatechinc.com
Country: United States
ProdList: 904
Advantage: 58

MilliporeSigma (Sigma-Aldrich Corp.)

Tel: --
Fax: --
Email: @sial.com
Country: United States
ProdList: 5414
Advantage: 58

VWR International, LLC.

Tel: --
Fax: --
Email: @sargentwelch.com
Country: United States
ProdList: 6262
Advantage: 58

SynQuest Laboratories, Inc. (Part of Central Glass Co., Ltd.)

Tel: --
Fax: --
Email: nfo@synquestlabs.com
Country: United States
ProdList: 1897
Advantage: 58

Dalton Research Molecules

Tel: --
Fax: --
Email: researchmolecules@dalton.com
Country: United States
ProdList: 44
Advantage: 58

Tyger Scientific Inc.

Tel: --
Fax: --
Email: sales@tygersci.com
Country: United States
ProdList: 402
Advantage: 58

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

Accela ChemBio Inc.

Tel: --
Fax: --
Email: info@accelachem.com
Country: United States
ProdList: 1054
Advantage: 50

Oakwood Products, Inc.

Tel: --
Fax: --
Email: sales@oakwoodchemical.com
Country: United States
ProdList: 6193
Advantage: 74

OX CHEM

Tel: --
Fax: --
Email: sales@ox-chem.com
Country: United States
ProdList: 759
Advantage: 50

American Elements, USA

Tel: --
Fax: --
Email: customerservice@americanelements.com
Country: United States
ProdList: 251
Advantage: 70

SynQuest Laboratories, Inc.

Tel: --
Fax: --
Email: info@synquestlabs.com
Country: United States
ProdList: 6871
Advantage: 62

TCI America

Tel: --
Fax: --
Email: sales@tciamerica.com
Country: United States
ProdList: 6909
Advantage: 75

Frontier Scientific, Inc.

Tel: --
Fax: --
Email: sales@frontiersci.com
Country: United States
ProdList: 6222
Advantage: 86

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

RnD SciChem, LLC

Tel: --
Fax: --
Email: rndscichem@gmail.com
Country: United States
ProdList: 569
Advantage: 0

Wilshire Chemical Company Inc.

Tel: --
Fax: --
Email: WilshrChem@AOL.COM
Country: United States
ProdList: 3498
Advantage: 58

CNH Technologies, Inc.

Tel: --
Fax: --
Email: info@cnhtechnologies.com
Country: United States
ProdList: 353
Advantage: 42

Aagile Labs Division of Tyger Scientific

Tel: --
Fax: --
Email: tygersci@yahoo.com
Country: United States
ProdList: 6568
Advantage: 68

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

AnaSpec, Inc.

Tel: --
Fax: --
Email: service@anaspec.com
Country: United States
ProdList: 4871
Advantage: 77

Medinoah Inc.

Tel: --
Fax: --
Email: info@medinoah.com
Country: United States
ProdList: 306
Advantage: 30

More

Less

View Lastest Price from 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine manufacturers

Nanjing Fred Technology Co., Ltd

Product: 4-Amino-3-Iodo-1H-Pyrazolo[3,4-D]Pyrimidine 151266-23-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1 ton
Release date: 2023-12-28

Henan Fengda Chemical Co., Ltd

Product: 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine 151266-23-8
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-09

Dideu Industries Group Limited

Product: 4-AMINO-3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDINE 151266-23-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-06

151266-23-8, 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine Related Search:

Zidovudine 3-BROMO-4-CHLORO-1H-PYRAZOLO[3,4-D]PYRIMIDINE DEAZAPURINE 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Trifluorothymine 2,4-DICHLORO-7H-PYRROLO2,3-DPYRIMIDINE 4-Amino-7H-pyrrolo[2,3-d]pyrimidine 2-Amino-4-chloropyrrolo[2,3-d]pyrimidine 2-Thiouracil 2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE 4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine Pyrrolo[2,3-d]pyrimidin-4-ol N4-Benzoylcytosine 4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE 4-Aminopyrazolo[3,4-d]pyrimidine 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one Ibrutinib Impurity 24

3-iodo-2H-pyrazolo[3,4-d]pyrimidin-4-amine

3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE

4-AMINO-3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDINE

4-Amino-3-iodopyrazolo[3,4-d]pyrimidine

1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-iodo-

4-Amino-3-iodo-1H-pyrazolo[3,4-D]pyridine

3-iodo-4-AMino-1H-pyrazolo[3,4-d]pyridine

7-Iodo-7-deaza-8-aza-adenine

3-iodopyrazolo[3,4-d]pyriMidin-4-aMine

4-AMino-3-iodopyrazolo[3,4-d]pyridine

3-iodo-4-aMino-1H-pyrazolo[3,4-d]pyriMidine

3-iodo-4-Aminopyrazolo[3,4-d]pyridine

3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine &gt

4-AMINO-3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDINE ISO 9001：2015 REACH

4-AMINO-3-IODO-1H-PYRAZOLO[3

TIANFU-CHEM - 4-AMINO-3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDINE

3-Iodo-4-amino-1H-pyrazolo[3,4-d]pyrimidine, 7-Iodo-7-deaza-8-azaadenine

3-iodo-5H-pyrazolo[3,4-d]pyrimidin-4-amine

4-AMINO-3-iodo-1H-Pyrazolo[3,4-D]Pyrimidin

3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine

IbrutinibIntermediate6

3-Lodo-1h-pyrazolo[3,4-d]pyrimidin-4-amine

151266-23-8

Heterocycle-Pyridine series

pharmacetical