1-N-BOC-PIPERIDINE-3-CARBOXAMIDE

Product Name: 1-N-BOC-PIPERIDINE-3-CARBOXAMIDE
CAS No.: 91419-49-7
Chemical Name: 1-N-BOC-PIPERIDINE-3-CARBOXAMIDE
Synonyms: BOC-3-Piperidine carboxamide;1-N-BOC-3-CARBAMOYLPIPERIDINE;N-BOC-3-PiperidineCarboxamide;1-Boc-3-piperidinecarboxamide;1-Boc-piperidine-3-carboxamide;N-BOC-piperidine-3-carboxamide;1-N-Boc-3-piperidinecarboxamide;1-N-BOC-PIPERIDINE-3-CARBOXAMIDE;1-Boc-3-(aMinocarbonyl)-piperidine;1-TERT-BUTOXYCARBONYL-3-METHYLAMINOPIPERIDINE
CBNumber: CB8359834
Molecular Formula: C11H20N2O3
Formula Weight: 228.29
MOL File: 91419-49-7.mol

More

Less

1-N-BOC-PIPERIDINE-3-CARBOXAMIDE Property

Melting point:: 174.0 to 178.0 °C
Boiling point:: 384.4±31.0 °C(Predicted)
Density: 1.123±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 16.41±0.20(Predicted)
color: White to Almost white

More

Less

Safety

Risk Statements: 22
Safety Statements: 37
HS Code: 29333990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: B5292
Product name: 1-(tert-Butoxycarbonyl)-3-piperidinecarboxamide
Purity: >98.0%(GC)
Packaging: 1g
Price: $34
Updated: 2025/07/31

TCI Chemical

Product number: B5292
Product name: 1-(tert-Butoxycarbonyl)-3-piperidinecarboxamide
Purity: >98.0%(GC)
Packaging: 5g
Price: $114
Updated: 2025/07/31

TRC

Product number: B646173
Product name: 1-BOC-3-Carbamoylpiperidine
Packaging: 500mg
Price: $75
Updated: 2021/12/16

Usbiological

Product number: 265816
Product name: 1-N-Boc-piperidine-3-carboxamide
Packaging: 500mg
Price: $333
Updated: 2021/12/16

Matrix Scientific

Product number: 075447
Product name: 1-Boc-3-Carbamoylpiperidine
Purity: 95+%
Packaging: 1g
Price: $10
Updated: 2021/12/16

More

Less

1-N-BOC-PIPERIDINE-3-CARBOXAMIDE Chemical Properties,Usage,Production

Chemical Properties

White powder

Synthesis Reference(s)

Synthetic Communications, 20, p. 1203, 1990 DOI: 10.1080/00397919008052828

Synthesis

71381-75-4

91419-49-7

General procedure for the synthesis of N-BOC-3-piperidinecarboxamide from 1-BOC-piperidine-3-carboxylic acid: To a chloroform solution (10 mL) of 1-Boc-piperidine-3-carboxylic acid (1.58 g, 6.89 mmol) was added drop-wise at 0 °C and under nitrogen protection, triethylamine (0.96 mL, 6.89 mmol) and ethyl chloroformate (0.69 mL, 7.23 mmol). The reaction mixture was stirred at 0°C for 10 min and then ammonia (gas) was passed for 1 hr. Subsequently, the reaction mixture was warmed to room temperature and stirring was continued for 3 hours. Upon completion of the reaction, 5% aqueous sodium bicarbonate solution was added to separate the organic and aqueous phases. The organic layer was dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the crude N-BOC-3-piperidinecarboxamide, which can be used in subsequent reactions without further purification. Yield: quantitative; LCMS (retention time): 3.31 min (Method A); mass spectrometry (electrospray positive ionization mode) showed m/z: 229.0 ([M+H]+).

References

[1] Patent: WO2006/123257, 2006, A2. Location in patent: Page/Page column 34
[2] Patent: US8080566, 2011, B1. Location in patent: Page/Page column 37-38
[3] European Journal of Medicinal Chemistry, 1984, vol. 19, # 2, p. 181 - 186
[4] Journal of Medicinal Chemistry, 2007, vol. 50, # 9, p. 2225 - 2239
[5] Patent: WO2014/149164, 2014, A1. Location in patent: Paragraph 00605

1-N-BOC-PIPERIDINE-3-CARBOXAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1-N-BOC-PIPERIDINE-3-CARBOXAMIDE Suppliers

Americas 1 Canada 1 China 95 Europe 1 India 3 Japan 1 United Kingdom 1 United States 13 Global 116

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

ForeChem (Nantong) Technology Co.,Ltd.

Tel: 513-85982855 18921614129
Fax: 051385915507
Email: sales@xianxingpharm.com
Country: China
ProdList: 2986
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd.

Tel: 21-54820552 18964669552
Fax: 086-21-64964478
Email: 188738128@qq.com
Country: China
ProdList: 310
Advantage: 66

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

More

Less

View Lastest Price from 1-N-BOC-PIPERIDINE-3-CARBOXAMIDE manufacturers

Wuhan Xinhao Biotechnology Co., Ltd

Product: 1-N-Boc-3-Carbamoyl-piperidine 91419-49-7
Price: US $10.00-6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000 Metric Ton/Month
Release date: 2024-03-11

Career Henan Chemical Co

Product: 1-N-BOC-PIPERIDINE-3-CARBOXAMIDE 91419-49-7
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: JD 535
Release date: 2019-09-01

91419-49-7, 1-N-BOC-PIPERIDINE-3-CARBOXAMIDERelated Search:

1-N-BOC-PIPERIDINE-4-CARBOXAMIDE,1-BOC-piperidine-4-carboxamide (+/-)-1-N-BOC-PIPERIDINE-2-CARBOXAMIDE 1-Boc-3-hydroxymethylpyrrolidine 1-Boc-4-cyanopiperidine N-Boc-3-Cyanopiperidine NIPECOTAMIDE Pipecolamide Hexahydroisonicotinamide 1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde N-Boc-4-piperidinemethanol 1-BOC-3-PIPERIDINECARBOXALDEHYDE N-BOC-3-Aminopiperidine 1-TERT-BUTYL 2-METHYL PIPERIDINE-1,2-DICARBOXYLATE N-BOC-piperidine-4-carboxylic acid N-Boc-2-piperidinecarboxylic acid Ethyl N-Boc-piperidine-4-carboxylate Ethyl 1-Boc-piperidine-2-carboxylate 1-Boc-3-hydroxypiperidine

3-CARBAMOYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

1-N-BOC-PIPERIDINE-3-CARBOXAMIDE

1-N-Boc-3-piperidinecarboxamide

1-TERT-BUTOXYCARBONYL-3-METHYLAMINOPIPERIDINE

1-Boc-piperidine-3-carboxamide

1-Piperidinecarboxylic acid, 3-(aminocarbonyl)-, 1,1-dimethylethyl ester

1-N-BOC-3-CARBAMOYLPIPERIDINE

tert-butyl 3-(aminocarbonyl)piperidine-1-carboxylate

1-Boc-3-piperidinecarboxamide

N-BOC-3-PiperidineCarboxamide

BOC-3-Piperidine carboxamide

N-BOC-piperidine-3-carboxamide

tert-butyl 3-carbaMoylpiperidine-1-carboxylate

1-Boc-3-(aMinocarbonyl)-piperidine

1-(tert-Butoxycarbonyl)-3-piperidinecarboxamide

3-Carbamoyl-1-piperidinecarboxylic Acid tert-Butyl Ester

tert-Butyl 3-Carbamoyl-1-piperidinecarboxylate

1-Piperidinecarboxylic acid, 3-(aminocarbonyl)-, 1,1-dimethy...

91419-49-7